日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens

鉴定一种对多重耐药细菌病原体具有强效外排泵抑制活性的新型多胺支架

Fleeman, Renee M; Debevec, Ginamarie; Antonen, Kirsten; Adams, Jessie L; Santos, Radleigh G; Welmaker, Gregory S; Houghten, Richard A; Giulianotti, Marc A; Shaw, Lindsey N

Differential regulation of alcohol taking and seeking by antagonism at α4β2 and α3β4 nAChRs

通过拮抗α4β2和α3β4 nAChRs来差异性调节酒精摄入和渴求

Cippitelli, Andrea; Brunori, Gloria; Schoch, Jennifer; Armishaw, Christopher J; Wu, Jinhua; Zaveri, Nurulain T; Giulianotti, Marc A; Welmaker, Gregory S; Toll, Lawrence

Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents

靶向拓扑异构酶I的小分子抑制剂作为新型抗结核药物

Sandhaus, Shayna; Annamalai, Thirunavukkarasu; Welmaker, Greg; Houghten, Richard A; Paz, Carlos; Garcia, Pamela K; Andres, Angelo; Narula, Gagandeep; Rodrigues Felix, Carolina; Geden, Sandra; Netherton, Mandy; Gupta, Rashmi; Rohde, Kyle H; Giulianotti, Marc A; Tse-Dinh, Yuk-Ching

Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines

小鼠直接表型筛选:从包含 734,821 个吡咯烷双哌嗪的化合物库中鉴定出单个新型镇痛化合物

Houghten, Richard A; Ganno, Michelle L; McLaughlin, Jay P; Dooley, Colette T; Eans, Shainnel O; Santos, Radleigh G; LaVoi, Travis; Nefzi, Adel; Welmaker, Greg; Giulianotti, Marc A; Toll, Lawrence

Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens

组合库作为发现针对 ESKAPE 病原体的新型广谱抗菌剂的工具

Renee Fleeman, Travis M LaVoi, Radleigh G Santos, Angela Morales, Adel Nefzi, Gregory S Welmaker, José L Medina-Franco, Marc A Giulianotti, Richard A Houghten, Lindsey N Shaw

Shifting from the single to the multitarget paradigm in drug discovery

药物研发从单靶点范式向多靶点范式的转变

Medina-Franco, José L; Giulianotti, Marc A; Welmaker, Gregory S; Houghten, Richard A