Auranofin inhibition of thioredoxin reductase sensitizes lung neuroendocrine tumor cells (NETs) and small cell lung cancer (SCLC) cells to sorafenib as well as inhibiting SCLC xenograft growth.
金诺芬抑制硫氧还蛋白还原酶,使肺神经内分泌肿瘤细胞(NETs)和小细胞肺癌(SCLC)细胞对索拉非尼敏感,并抑制SCLC异种移植瘤的生长
期刊:Cancer Biology & Therapy
影响因子:4.6
doi:10.1080/15384047.2024.2382524
Johnson Spenser S, Liu Dijie, Ewald Jordan T, Robles-Planells Claudia, Pulliam Casey, Christensen Keegan A, Bayanbold Khaliunaa, Wels Brian R, Solst Shane R, O'Dorisio M Sue, Menda Yusuf, Spitz Douglas R, Fath Melissa A