日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

DksA inhibitors against intracellular and persistent Salmonella are effective in acute models of infection

DksA抑制剂对胞内和持续性沙门氏菌感染有效，在急性感染模型中均有应用。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.aea6832
Kim, Ju-Sim; Kumar, Vijay; Liu, Lin; Choi, Yu J; Senovaityte, Simona; McCollister, Bruce D; Wlodarchak, Nathan; Orlicky, David J; Rice, Peter J; Dai, Shaodong; Wempe, Michael F; Vázquez-Torres, Andrés
炎症/感染
发表日期：2026
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Endogenous protein tagging coupled with a CRISPR screening approach identifies UBE3C as a potential MYC oncogene regulator.

内源性蛋白质标记结合 CRISPR 筛选方法鉴定出 UBE3C 为潜在的 MYC 癌基因调节因子。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-47974-w
Seibert Marcel, Kurrle Nina, Kaleab Sifora, Wempe Frank, von Metzler Ivana, Serve Hubert, Schnütgen Frank
肿瘤
MYC
UBE3C
发表日期：2026
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Ionized magnesium levels and atrial fibrillation in patients undergoing cardiac surgery - The iMagic Prospective Cohort Study

接受心脏手术患者的离子镁水平与心房颤动的关系——iMagic前瞻性队列研究

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0345860
Sadjadi, Mahan; von Groote, Thilo; Krone, Sina; Schöne, Ludwig Maximilian; Strauß, Christian; Mertes, Moritz J; Martin, Christine; Dinkel, Felix; Schellnack, Jessica; Fraune, Thomas; Wempe, Carola; Zarbock, Alexander; Booke, Hendrik; Gottschalk, Antje
发表日期：2026
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Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice

鉴定出一种共同的酮己糖激酶依赖性联系，该联系驱动小鼠的酒精摄入和酒精相关性肝病。

期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-025-01402-x
Andres-Hernando, Ana; Orlicky, David J; Garcia, Gabriela E; Loetz, Esteban C; Montoya, Richard; Kumar, Vijay; Effinger, Devin P; Kuwabara, Masanari; Bae, So Young; Lorenzo-Rebenaque, Laura; Fauste, Elena; Bell, Richard L; Grahame, Nicholas; Liangpunsakul, Suthat; Kim, Hahn; Dugar, Sundeep; Maffuid, Paul; Nakagawa, Takahiko; Wempe, Michael F; Petrash, J Mark; Tolan, Dean R; Bland, Sondra T; Johnson, Richard J; Lanaspa, Miguel A
信号转导
发表日期：2025
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Ruxolitinib-dependent reduction of seizure load and duration is accompanied by spatial memory improvement in the rat pilocarpine model of temporal lobe epilepsy

在毛果芸香碱诱导的大鼠颞叶癫痫模型中，鲁索替尼可降低癫痫发作的次数和持续时间，并伴有空间记忆的改善。

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2024.e00506
Carrel, Andrew; Napoli, Eleonora; Hixson, Kathryn; Carlsen, Jessica; Cruz Del Angel, Yasmin; Strode, Dana; Busquet, Nicolas; Kumar, Vijay; Wempe, Michael F; Russek, Shelley J; Brooks-Kayal, Amy R
癫痫
Rat
神经科学
发表日期：2025
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The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir.

lenacapavir 高效抑制 HIV-1 成熟的主要机制

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1012862
Huang Szu-Wei, Briganti Lorenzo, Annamalai Arun S, Greenwood Juliet, Shkriabai Nikoloz, Haney Reed, Armstrong Michael L, Wempe Michael F, Singh Satya Prakash, Francis Ashwanth C, Engelman Alan N, Kvaratskhelia Mamuka
信号转导
发表日期：2025
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Endocrine-Disrupting Activities of Flavones on Steroid Receptors: Structural Requirements and Synthesis of Novel Flavone with Improved Estrogenic Activity

黄酮类化合物对类固醇受体的内分泌干扰活性：结构要求及新型黄酮的合成及其雌激素活性的增强

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13030748
Nordeen, Steven K; Kumar, Vijay; Bona, Betty J; Batson, Joshua D; Backos, Donald S; Wempe, Michael F
信号转导
免疫/内分泌
发表日期：2025
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Assessment of urinary 6-oxo-pipecolic acid as a biomarker for ALDH7A1 deficiency

评估尿液中6-氧代哌啶酸作为ALDH7A1缺乏症生物标志物的价值

期刊:Journal of Inherited Metabolic Disease
影响因子:3.8
doi:10.1002/jimd.12783
Khalil, Youssef; Footitt, Emma; Vootukuri, Reddy; Wempe, Michael F; Coughlin, Curtis R 2nd; Batzios, Spyros; Wilson, Matthew P; Kožich, Viktor; Clayton, Peter T; Mills, Philippa B
ALDH
发表日期：2025
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Feasibility of newborn screening for pyridoxine-dependent epilepsy

新生儿吡哆醇依赖性癫痫筛查的可行性

期刊:Molecular Genetics and Metabolism
影响因子:3.5
doi:10.1016/j.ymgme.2024.109002
Pauly, Kristine; Woontner, Michael; Abdenur, Jose E; Chaudhari, Bimal P; Gosselin, Rachel; Kripps, Kimberly A; Thomas, Janet A; Wempe, Michael F; Gospe, Sidney M Jr; Coughlin, Curtis R 2nd
癫痫
神经科学
发表日期：2025
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Effects of an extended therapeutic strategy versus standard-of-care therapy on persistent acute kidney injury in high-risk patients after major surgery: study protocol for the randomised controlled single-centre PrevProgAKI trial

延长治疗策略与标准治疗方案对高危患者大手术后持续性急性肾损伤的影响：随机对照单中心 PrevProgAKI 试验的研究方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2024-097333
Sadjadi, Mahan; Strauß, Christian; von Groote, Thilo; Booke, Hendrik; Schöne, Ludwig Maximilian; Sauermann, Leonie; Wempe, Carola; Gerss, Joachim; Kellum, John; Meersch, Melanie; Zarbock, Alexander
毒理研究
肾损伤
发表日期：2025
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