Wen Xuan相关文献与解析，生知库 | 链接生命科学的每一步

In vivo Expansion of Regulatory T cells via an Engineered IL-2 Mutein to Suppress Autoimmune Glomerulonephritis

利用基因工程改造的IL-2突变体在体内扩增调节性T细胞以抑制自身免疫性肾小球肾炎

Kuang, Huang; Lin, Cai-Xia; Huang, Jing; Li, Wen-Xuan; Zhu, Yu-Ge; Jiang, Nan; Li, Zhong; Li, Nan; Li, Ping; Jia, Xiao-Yu; Cui, Zhao; Zhao, Ming-Hui

肾炎

Gastrodin alleviates high fructose-induced podocyte mitochondria-mediated apoptosis by inhibiting NLRP6 to facilitate TRIM7-triggered Bok mRNA degradation.

天麻素通过抑制 NLRP6 来促进 TRIM7 触发的 Bok mRNA 降解，从而减轻高果糖诱导的足细胞线粒体介导的细胞凋亡。

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.120307

Ding Hong, Wang Wen-Xuan, Liang Qiong-Dan, Tang Chuan-Feng, Xu Tang-Di, Miao Zi-An, Han Bang-Xing, Kong Ling-Dong

E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival

E3连接酶AREL1控制溶酶体的核周定位并支持浦肯野细胞的存活

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/s44318-025-00654-3

Jiang, Luyi; Tang, Jiangfen; Zhang, Ya-Fen; Zou, Wen-Xuan; Deng, Gang; Tian, Na; Zhao, Xiaolu; Han, Lei; Liu, Kai; Song, Bao-Liang; Luo, Jie

细胞生物学

发表日期：2026

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Design and Synthesis of Marine Sarocladione Derivatives with Potential Anticancer Activity

设计并合成具有潜在抗癌活性的海洋沙罗克拉酮衍生物

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md24010048

Liu, Xiao-Mei; Li, Wen-Xuan; Kong, Ling-Xiu; Han, Guan-Ying; Gui, Jinghan; Li, Xu-Wen

TIA1 Mutant Mouse Model Exhibits Motor Deficits and Neurodegenerative Characteristics of Amyotrophic Lateral Sclerosis.

TIA1 突变小鼠模型表现出肌萎缩侧索硬化症的运动障碍和神经退行性特征。

期刊:Cells

影响因子:5.2

doi:10.3390/cells15050420

Mao Li-Hong, Song Yu-Ning, Zhang Jing-Qi, Shao Yun-Ting, Wang Zhang-Li, Yang Na, Zhang Wen-Xuan, Zhang Ying-Rui, Gao Xiao-Yan, Li Jia-Yi, Yuan Lin

Peniexpansones A-F: polyketides from Penicillium expansum DWS880 capable of enhancing the activity of fluconazole against Candida albicans

Peniexpansones AF：来自扩展青霉DWS880的聚酮化合物，能够增强氟康唑对白色念珠菌的活性

期刊:Natural Products and Bioprospecting

影响因子:4.9

doi:10.1007/s13659-026-00592-5

Lu, Wen-Yu; Xiao, Qing-Hui; Liang, Ai-Lin; Xu, Peng-Ju; Li, Jing; Wang, Wen-Xuan

发表日期：2026

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Screening for Cognitive Decline in Psychotic Disorders in Midlife: Examining Scoring the Clinical Dementia Rating Using Longitudinal Data

中年精神病性障碍患者认知衰退筛查：利用纵向数据检验临床痴呆评定量表评分

期刊:Schizophrenia Bulletin

影响因子:4.8

doi:10.1093/schbul/sbaf080

Clouston, Sean A P; Jonas, Katherine; Lyketsos, Constantine G; Lian, Wen Xuan; Yang, Yuan; Harvey, Philip D; Bromet, Evelyn J; Kotov, Roman

神经科学

发表日期：2026

文献求助收藏

Two distinct attentional priorities guide exploratory and exploitative gaze

探索性凝视和利用性凝视分别由两种不同的注意力优先顺序引导。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2026.115218

Wen, Xuan; Hassani, Alireza Seyed; Neumann, Adam; Tiesinga, Paul; Womelsdorf, Thilo

发表日期：2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

牙龈卟啉单胞菌通过PPARγ-LXRα-ABCA1/ABCG1信号通路引发动脉粥样硬化中的脂质代谢紊乱。

期刊:Molecular Medicine Reports

影响因子:3.5

doi:10.3892/mmr.2026.13880

Lin, Xue-Jing; Yao, Min; Lin, Wan-Yun; Yuan, Qin; Zhou, Jie; Xia, Wen-Xuan; Dong, Yu-Lei; Zhang, Miao-Miao; Cui, Ming-Wang; Wu, Lin-Han; Sunchuri, Diwas; Ullah Shahid, Muhammad Zia; Guo, Zhu-Ling

Quantum phases in twisted homobilayer transition metal dichalcogenides

扭曲同质双层过渡金属二硫化物中的量子相

In vivo Expansion of Regulatory T cells via an Engineered IL-2 Mutein to Suppress Autoimmune Glomerulonephritis

利用基因工程改造的IL-2突变体在体内扩增调节性T细胞以抑制自身免疫性肾小球肾炎

Gastrodin alleviates high fructose-induced podocyte mitochondria-mediated apoptosis by inhibiting NLRP6 to facilitate TRIM7-triggered Bok mRNA degradation.

天麻素通过抑制 NLRP6 来促进 TRIM7 触发的 Bok mRNA 降解，从而减轻高果糖诱导的足细胞线粒体介导的细胞凋亡。

E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival

E3连接酶AREL1控制溶酶体的核周定位并支持浦肯野细胞的存活

Design and Synthesis of Marine Sarocladione Derivatives with Potential Anticancer Activity

设计并合成具有潜在抗癌活性的海洋沙罗克拉酮衍生物

TIA1 Mutant Mouse Model Exhibits Motor Deficits and Neurodegenerative Characteristics of Amyotrophic Lateral Sclerosis.

TIA1 突变小鼠模型表现出肌萎缩侧索硬化症的运动障碍和神经退行性特征。

Peniexpansones A-F: polyketides from Penicillium expansum DWS880 capable of enhancing the activity of fluconazole against Candida albicans

Peniexpansones AF：来自扩展青霉DWS880的聚酮化合物，能够增强氟康唑对白色念珠菌的活性

Screening for Cognitive Decline in Psychotic Disorders in Midlife: Examining Scoring the Clinical Dementia Rating Using Longitudinal Data

中年精神病性障碍患者认知衰退筛查：利用纵向数据检验临床痴呆评定量表评分

Two distinct attentional priorities guide exploratory and exploitative gaze

探索性凝视和利用性凝视分别由两种不同的注意力优先顺序引导。

Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

牙龈卟啉单胞菌通过PPARγ-LXRα-ABCA1/ABCG1信号通路引发动脉粥样硬化中的脂质代谢紊乱。