Weng-In相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.

在小鼠和猪动物模型中对视网膜下注射的 Cas9 核糖核蛋白进行评估，突显了基因药物治疗转化中的关键考虑因素

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0317387

Wei Spencer C, Cantor Aaron J, Walleshauser Jack, Mepani Rina, Melton Kory, Bans Ashil, Khekare Prachi, Gupta Suhani, Wang Jonathan, Soares Craig, Kiwan Radwan, Lee Jieun, McCawley Shannon, Jani Vihasi, Leong Weng In, Shahi Pawan K, Chan Jean, Boivin Pierre, Otoupal Peter, Pattnaik Bikash R, Gamm David M, Saha Krishanu, Gowen Benjamin G, Haak-Frendscho Mary, Janatpour Mary J, Silverman Adam P

免疫/内分泌

发表日期：2025

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Systematic identification and characterization of high efficiency Cas9 guide RNAs for therapeutic targeting of ADAR.

系统地鉴定和表征用于ADAR治疗靶向的高效Cas9引导RNA

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0317745

Gowen Benjamin G, Melton Kory, Leong Weng In, Khekare Prachi, McCawley Shannon, Chan Jean, Boivin Pierre, Jani Vihasi, Cantor Aaron J, Tambe Akshay, Haak-Frendscho Mary, Janatpour Mary J, Wei Spencer C

发表日期：2025

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Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines

在小鼠和猪动物模型中对视网膜下递送 Cas9 核糖核蛋白的评估突出了基因药物治疗转化的关键考虑因素

doi:10.1101/2024.12.30.630799

Spencer C Wei, Aaron J Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Ashil Bans, Prachi Khekare, Suhani Gupta, Jonathan Wang, Craig Soares, Radwan Kiwan, Jieun Lee, Shannon McCawley, Vihasi Jani, Weng In Leong, Pawan K Shahi, Jean Chan, Pierre Boivin, Peter Otoupal, Bikash R Pattnaik, David M

发表日期：2024

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Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae

来自加勒比海帕利索亚藻的毒性肽作用于TRPV1通道，可预防戊四唑诱导的斑马鱼幼虫癫痫

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2021.763089

Wang, Xiufen; Liao, Qiwen; Chen, Hanbin; Gong, Guiyi; Siu, Shirley Weng In; Chen, Qian; Kam, Hiotong; Ung, Carolina Oi Lam; Cheung, Kwok-Kuen; Rádis-Baptista, Gandhi; Wong, Clarence Tsun Ting; Lee, Simon Ming-Yuen

发表日期：2021

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BESTox: A Convolutional Neural Network Regression Model Based on Binary-Encoded SMILES for Acute Oral Toxicity Prediction of Chemical Compounds

BESTox：一种基于二元编码SMILES的卷积神经网络回归模型，用于预测化合物的急性口服毒性

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules25092215

Kim, Hyun Su; Chung, Sungkyun; Song, Moon-Young; Lim, Changjin; Shin, Hyeyoung; Hur, Joonseong; Kwon, Hyuk; Suh, Young-Ger; Kim, Eun-Hee; Shin, Dongyun; Kim, Seok-Ho; Chen, Jiarui; Cheong, Hong-Hin; Siu, Shirley Weng In

发表日期：2020

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Chemerin Suppresses Breast Cancer Growth by Recruiting Immune Effector Cells Into the Tumor Microenvironment.

Chemerin通过将免疫效应细胞募集到肿瘤微环境中来抑制乳腺癌的生长

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2019.00983

Pachynski Russell K, Wang Ping, Salazar Nicole, Zheng Yayue, Nease Leona, Rosalez Jesse, Leong Weng-In, Virdi Gurpal, Rennier Keith, Shin Woo Jae, Nguyen Viet, Butcher Eugene C, Zabel Brian A

细胞生物学

发表日期：2019

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Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses

低剂量节拍环磷酰胺可补充肿瘤内 C 类 CpG TLR9 激动剂的作用，增强先天免疫力并驱动强大的 T 细胞介导的抗肿瘤反应

期刊:Oncotarget

doi:10.18632/oncotarget.27322

Weng In Leong, Rachel Y Ames, Jessica M Haverkamp, Laura Torres, Janine Kline, Ashil Bans, Lauren Rocha, Marilena Gallotta, Cristiana Guiducci, Robert L Coffman, Mary J Janatpour

发表日期：2019

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A Novel ShK-Like Toxic Peptide from the Transcriptome of the Cnidarian Palythoa caribaeorum Displays Neuroprotection and Cardioprotection in Zebrafish

来自刺胞动物加勒比海帕利索亚虫转录组的新型ShK样毒性肽在斑马鱼中表现出神经保护和心脏保护作用

doi:10.3390/toxins10060238

Liao, Qiwen; Gong, Guiyi; Siu, Shirley Weng In; Wong, Clarence Tsun Ting; Yu, Huidong; Tse, Yu Chung; Rádis-Baptista, Gandhi; Lee, Simon Ming-Yuen

发表日期：2018

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FetalQuant(SD): accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA

FetalQuant(SD)：通过对母体血浆DNA进行浅层测序，精确量化胎儿DNA含量

期刊:npj Genomic Medicine

影响因子:4.8

doi:10.1038/npjgenmed.2016.13

Jiang, Peiyong; Peng, Xianlu; Su, Xiaoxi; Sun, Kun; Yu, Stephanie C Y; Chu, Weng In; Leung, Tak Y; Sun, Hao; Chiu, Rossa W K; Lo, Yuk Ming Dennis; Chan, Kwan Chee Allen

发表日期：2016

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Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway

鞘氨醇-1-磷酸通过 S1PR2/STAT3 信号通路增强营养不良肌肉中的卫星细胞活化

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0037218

Kenneth C Loh, Weng-In Leong, Morgan E Carlson, Babak Oskouian, Ashok Kumar, Henrik Fyrst, Meng Zhang, Richard L Proia, Eric P Hoffman, Julie D Saba

细胞生物学

发表日期：2012

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