日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines

在小鼠和猪动物模型中对视网膜下递送 Cas9 核糖核蛋白的评估突出了基因药物治疗转化的关键考虑因素

Spencer C Wei, Aaron J Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Ashil Bans, Prachi Khekare, Suhani Gupta, Jonathan Wang, Craig Soares, Radwan Kiwan, Jieun Lee, Shannon McCawley, Vihasi Jani, Weng In Leong, Pawan K Shahi, Jean Chan, Pierre Boivin, Peter Otoupal, Bikash R Pattnaik, David M

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses

低剂量节拍环磷酰胺可补充肿瘤内 C 类 CpG TLR9 激动剂的作用,增强先天免疫力并驱动强大的 T 细胞介导的抗肿瘤反应

Weng In Leong, Rachel Y Ames, Jessica M Haverkamp, Laura Torres, Janine Kline, Ashil Bans, Lauren Rocha, Marilena Gallotta, Cristiana Guiducci, Robert L Coffman, Mary J Janatpour

Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway

鞘氨醇-1-磷酸通过 S1PR2/STAT3 信号通路增强营养不良肌肉中的卫星细胞活化

Kenneth C Loh, Weng-In Leong, Morgan E Carlson, Babak Oskouian, Ashok Kumar, Henrik Fyrst, Meng Zhang, Richard L Proia, Eric P Hoffman, Julie D Saba