日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP

一种非环状核苷膦酸酯通过抑制环磷酸鸟苷(cGMP)的合成,有效阻断疟原虫的逸出。

Ali, Marie; Dura, Rea; Guery, Marc-Antoine; Colard-Itté, Emma; Cheviet, Thomas; Robresco, Léa; Berry, Laurence; Lionne, Corinne; Lavazec, Catherine; Claessens, Antoine; Peyrottes, Suzanne; Wengelnik, Kai; Wein, Sharon; Cerdan, Rachel

PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum.

PI3激酶在恶性疟原虫的无性血液阶段具有多种功能

Al Monla Reem, Penzo Maria, Vallentin Alice, Lohia Rakhee, Vincent Jeremy, Berry Laurence, Gomes Ana Rita, Cerdan Rachel, Wengelnik Kai

Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion

人类红细胞中 PIEZO1 的药理激活可阻止恶性疟原虫入侵

Rakhee Lohia, Benoit Allegrini, Laurence Berry, Hélène Guizouarn, Rachel Cerdan, Manouk Abkarian, Dominique Douguet, Eric Honoré, Kai Wengelnik

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.

非洲人群中常见的 PIEZO1 等位基因会导致红细胞脱水并减弱疟原虫感染

Ma Shang, Cahalan Stuart, LaMonte Gregory, Grubaugh Nathan D, Zeng Weizheng, Murthy Swetha E, Paytas Emma, Gamini Ramya, Lukacs Viktor, Whitwam Tess, Loud Meaghan, Lohia Rakhee, Berry Laurence, Khan Shahid M, Janse Chris J, Bandell Michael, Schmedt Christian, Wengelnik Kai, Su Andrew I, Honore Eric, Winzeler Elizabeth A, Andersen Kristian G, Patapoutian Ardem

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

前体在疟原虫磷脂代谢中的贡献和途径的相互作用

Sharon Wein, Salma Ghezal, Corinne Buré, Marjorie Maynadier, Christian Périgaud, Henri J Vial, Isabelle Lefebvre-Tournier, Kai Wengelnik, Rachel Cerdan

Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell

伯氏疟原虫配子体从红细胞逸出过程中发生的膜破裂和囊泡形成

Andreadaki, Maria; Hanssen, Eric; Deligianni, Elena; Claudet, Cyrille; Wengelnik, Kai; Mollard, Vanessa; McFadden, Geoffrey I; Abkarian, Manouk; Braun-Breton, Catherine; Siden-Kiamos, Inga

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

疟原虫基因组的功能分析揭示了大量必需基因

Ellen Bushell, Ana Rita Gomes, Theo Sanderson, Burcu Anar, Gareth Girling, Colin Herd, Tom Metcalf, Katarzyna Modrzynska, Frank Schwach, Rowena E Martin, Michael W Mather, Geoffrey I McFadden, Leopold Parts, Gavin G Rutledge, Akhil B Vaidya, Kai Wengelnik, Julian C Rayner, Oliver Billker

High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death

新型抗疟药阿比特唑的高蓄积性和体内循环利用导致寄生虫迅速死亡

Wein, Sharon; Taudon, Nicolas; Maynadier, Marjorie; Tran Van Ba, Christophe; Margout, Delphine; Bordat, Yann; Fraisse, Laurent; Wengelnik, Kai; Cerdan, Rachel; Bressolle-Gomeni, Françoise; Vial, Henri J

Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii

脂质激酶对于弓形虫顶质体稳态至关重要

Daher, Wassim; Morlon-Guyot, Juliette; Sheiner, Lilach; Lentini, Gaëlle; Berry, Laurence; Tawk, Lina; Dubremetz, Jean-François; Wengelnik, Kai; Striepen, Boris; Lebrun, Maryse

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis

磷脂酰肌醇3-单磷酸参与弓形虫顶质体的生物合成。

Tawk, Lina; Dubremetz, Jean-François; Montcourrier, Philippe; Chicanne, Gaëtan; Merezegue, Fabrice; Richard, Véronique; Payrastre, Bernard; Meissner, Markus; Vial, Henri J; Roy, Christian; Wengelnik, Kai; Lebrun, Maryse