日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC

KRASG12D 驱动的戊糖磷酸途径重塑赋予可靶向的脆弱性，与 MRTX1133 协同作用，实现 PDAC 的持久缓解

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.101966
Xiangyan Jiang, Tao Wang, Bin Zhao, Haonan Sun, Yuman Dong, Yong Ma, Zhigang Li, Yuxia Wu, Keshen Wang, Xiaoying Guan, Bo Long, Long Qin, Wengui Shi, Lei Shi, Qichen He, Wenbo Liu, Mingdou Li, Lixia Xiao, Chengliang Zhou, Hui Sun, Jing Yang, Junhong Guan, Huinian Zhou, Zeyuan Yu, Zuoyi Jiao1
RAS
发表日期：2025
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Gastric cancer-derived exosomal let-7 g-5p mediated by SERPINE1 promotes macrophage M2 polarization and gastric cancer progression

SERPINE1介导胃癌来源的外泌体let-7g-5p促进巨噬细胞M2极化及胃癌进展

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-024-03269-4
Zhenzhen Ye #, Jianfeng Yi #, Xiangyan Jiang, Wengui Shi, Hao Xu, Hongtai Cao, Long Qin, Lixin Liu, Tianming Wang, Zhijian Ma, Zuoyi Jiao
免疫
细胞生物学
胃癌
巨噬细胞
发表日期：2025
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ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation

ULBP2 CAR-T细胞通过抑制CAF活化增强胃癌免疫疗法

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-025-07905-5
Wentao Zhang # ，Wen Ren # ，Shuyan Guo # ，Haobo Han ，Weiwen Cai ，Haowen Bai ，Long Li ，Xiangyan Jiang ，Xin Zheng ，Tiansheng Zhang ，Yan Wang ，Huili Ye ，Hongtai Cao ，Wengui Shi ，Huinian Zhou ，Zeyuan Yu ，Long Qin ，Zuoyi Jiao
T细胞
细胞生物学
肿瘤
T细胞
肿瘤免疫
胃癌
LBP
免疫/内分泌
发表日期：2025
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Therapeutic potential of SHCBP1 inhibitor AZD5582 in pancreatic cancer treatment

SHCBP1抑制剂AZD5582在胰腺癌治疗中的治疗潜力

期刊:Cancer Science
影响因子:4.5
doi:10.1111/cas.16059
Zhijian Ma, Qianlin Gu, Yiwei Dai, Qiaoyan Wang, Wengui Shi, Zuoyi Jiao
肿瘤
胰腺癌
发表日期：2024
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Knockout of Shcbp1 sensitizes immunotherapy by regulating α-SMA positive cancer-associated fibroblasts

Shcbp1 敲除通过调节 α-SMA 阳性癌症相关成纤维细胞增强免疫疗法的敏感性

期刊:Molecular Carcinogenesis
影响因子:3
doi:10.1002/mc.23675
Qianlin Gu, Zhijian Ma, Qiaoyan Wang, Yiwei Dai, Wengui Shi, Zuoyi Jiao
肿瘤
成纤维细胞
发表日期：2024
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Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress

靶向 UBE2T 通过调节嘧啶代谢和复制应激增强吉西他滨对胰腺癌的疗效

期刊:Gastroenterology
影响因子:25.7
doi:10.1053/j.gastro.2023.02.025
Xiangyan Jiang, Yong Ma, Tao Wang, Huinian Zhou, Keshen Wang, Wengui Shi, Long Qin, Junhong Guan, Lianshun Li, Bo Long, Jianli Wang, Xiaoying Guan, Huili Ye, Jing Yang, Zeyuan Yu, Zuoyi Jiao
代谢
肿瘤
胰腺癌
发表日期：2023
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PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer

PICH 激活细胞周期蛋白 A1 转录，推动胃癌 S 期进展和化学耐药性

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-23-1331
Huili Ye #, Wengui Shi #, Jing Yang, Long Wang, Xiangyan Jiang, Huiming Zhao, Long Qin, Junjie Qin, Lianshun Li, Weiwen Cai, Junhong Guan, Hanteng Yang, Huinian Zhou, Zeyuan Yu, Hui Sun, Zuoyi Jiao
肿瘤
胃癌
其它细胞
发表日期：2023
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Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer

靶向uPAR的治疗策略可增强弥漫型胃癌中抗PD-1的疗效

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.abn3774
Long Qin ，Long Wang ，Junchang Zhang ，Huinian Zhou ，Zhiliang Yang ，Yan Wang ，Weiwen Cai ，Fei Wen ，Xiangyan Jiang ，Tiansheng Zhang ，Huili Ye ，Bo Long ，Junjie Qin ，Wengui Shi ，Xiaoying Guan ，Zeyuan Yu ，Jing Yang ，Qi Wang ，Zuoyi Jiao
肿瘤免疫
PD-1
胃癌
uPA
肿瘤
uPAR
发表日期：2022
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Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer

HER2-SHCBP1-PLK1轴过度激活促进肿瘤细胞有丝分裂并削弱曲妥珠单抗对胃癌的敏感性

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-23053-8
Wengui Shi #, Gengyuan Zhang #, Zhijian Ma #, Lianshun Li #, Miaomiao Liu, Long Qin, Zeyuan Yu, Lei Zhao, Yang Liu, Xue Zhang, Junjie Qin, Huili Ye, Xiangyan Jiang, Huinian Zhou, Hui Sun, Zuoyi Jiao
肿瘤
胃癌
肿瘤细胞
发表日期：2021
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A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination

新型 UBE2T 抑制剂通过阻断 RACK1 泛素化来抑制 Wnt/β-catenin 信号过度激活和胃癌进展

期刊:Oncogene
影响因子:6.9
doi:10.1038/s41388-020-01572-w
Zeyuan Yu #, Xiangyan Jiang #, Long Qin, Haixiao Deng, Jianli Wang, Wen Ren, Hongbin Li, Lei Zhao, Huanxiang Liu, Hong Yan, Wengui Shi, Qi Wang, Changjiang Luo, Bo Long, Huinian Zhou, Hui Sun, Zuoyi Jiao
肿瘤
胃癌
Wnt/β-Catenin
发表日期：2021
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