日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational Dynamics of the Activated GLP-1 Receptor-Gs Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling

交联质谱和综合结构建模揭示活化 GLP-1 受体-Gs 复合物的构象动力学

Shijia Yuan, Lisha Xia, Chenxi Wang, Fan Wu, Bingjie Zhang, Chen Pan, Zhiran Fan, Xiaoguang Lei, Raymond C Stevens, Andrej Sali, Liping Sun, Wenqing Shui

Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα

纳米抗体和化学交联促进 PI3Kα 的结构和功能分析

Jonathan R Hart, Xiao Liu, Chen Pan, Anyi Liang, Lynn Ueno, Yingna Xu, Alexandra Quezada, Xinyu Zou, Su Yang, Qingtong Zhou, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, Tian Xia, Wenqing Shui, Dehua Yang, Peter K Vogt, Ming-Wei Wang

Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression

大脑跨膜蛋白质组的多区域分析揭示了抑郁症的新调节因子

Shanshan Li, Huoqing Luo, Ronghui Lou, Cuiping Tian, Chen Miao, Lisha Xia, Chen Pan, Xiaoxiao Duan, Ting Dang, Hui Li, Chengyu Fan, Pan Tang, Zhuangzhuang Zhang, Yan Liu, Yunxia Li, Fei Xu, Yaoyang Zhang, Guisheng Zhong, Ji Hu, Wenqing Shui

Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

超分辨率荧光成像揭示神经元中大麻素受体的有序分布

Hui Li ,Jie Yang ,Cuiping Tian ,Min Diao ,Quan Wang ,Simeng Zhao ,Shanshan Li ,Fangzhi Tan ,Tian Hua ,Ya Qin ,Chao-Po Lin ,Dylan Deska-Gauthier ,Garth J Thompson ,Ying Zhang ,Wenqing Shui ,Zhi-Jie Liu ,Tong Wang ,Guisheng Zhong

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

米索前列醇与催产剂前列腺素 E2 受体结合的晶体结构

Martin Audet, Kate L White, Billy Breton, Barbara Zarzycka, Gye Won Han, Yan Lu, Cornelius Gati, Alexander Batyuk, Petr Popov, Jeffrey Velasquez, David Manahan, Hao Hu, Uwe Weierstall, Wei Liu, Wenqing Shui, Vsevolod Katritch, Vadim Cherezov, Michael A Hanson, Raymond C Stevens2

Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor

加速基于亲和质谱的 G 蛋白偶联受体配体筛选的通量

Yan Lu, Shanshan Qin, Bingjie Zhang, Antao Dai, Xiaoqing Cai, Mengna Ma, Zhan-Guo Gao, Dehua Yang, Raymond C Stevens, Kenneth A Jacobson, Ming-Wei Wang, Wenqing Shui

High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening

通过亲和质谱筛选高通量鉴定G蛋白偶联受体调节剂

Shanshan Qin, Mengmeng Meng, Dehua Yang, Wenwen Bai, Yan Lu, Yao Peng, Gaojie Song, Yiran Wu, Qingtong Zhou, Suwen Zhao, Xiping Huang, John D McCorvy, Xiaoqing Cai, Antao Dai, Bryan L Roth, Michael A Hanson, Zhi-Jie Liu, Ming-Wei Wang, Raymond C Stevens, Wenqing Shui

Identification of natural products as novel ligands for the human 5-HT2C receptor

鉴定天然产物作为人类 5-HT2C 受体的新型配体

Yao Peng, Simeng Zhao, Yiran Wu, Haijie Cao, Yueming Xu, Xiaoyan Liu, Wenqing Shui, Jianjun Cheng, Suwen Zhao, Ling Shen, Jun Ma, Ronald J Quinn, Raymond C Stevens, Guisheng Zhong, Zhi-Jie Liu

Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae

定量蛋白质组学揭示酿酒酵母管状内质网中富集的蛋白质

Xinbo Wang, Shanshan Li, Haicheng Wang, Wenqing Shui, Junjie Hu

Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules

Tudor-SN 是 JNK 的一种新型底物,其磷酸化与 Tudor-SN 有效募集到应激颗粒有关

Chao Su, Xingjie Gao, Wendong Yang, Yali Zhao, Xue Fu, Xiaoteng Cui, Chunyan Zhang, Lingbiao Xin, Yuanyuan Ren, Lixin Li, Wenqing Shui, Xi Yang, Minxin Wei, Jie Yang