Werner Held相关文献与解析，生知库 | 链接生命科学的每一步

Bing Feng # ，Zhiliang Bai # ，Xiaolei Zhou ，Yang Zhao ，Yu-Qing Xie ，Xinyi Huang ，Yang Liu ，Tom Enbar ，Rongrong Li ，Yi Wang ，Min Gao ，Lucia Bonati ，Mei-Wen Peng ，Weilin Li ，Bo Tao ，Mélanie Charmoy ，Werner Held ，J Joseph Melenhorst ，Rong Fan ，Yugang Guo ，Li Tang

IL-4

免疫/内分泌

T细胞

Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis

荧光报告基因微环境定位标记策略在实验性脑转移瘤中的应用研究

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.110284

Matteo Massara ，Bastien Dolfi ，Vladimir Wischnewski ，Emma Nolan ，Werner Held ，Ilaria Malanchi ，Johanna A Joyce

神经科学

发表日期：2024

文献求助收藏

Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells

移植物抗宿主病是由靶组织中驻留的祖细胞样T细胞在局部维持的。

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2023.01.003

Faruk Sacirbegovic ，Matthias Günther ，Alessandro Greco ，Daqiang Zhao ，Xi Wang ，Meng Zhou ，Sarah Rosenberger ，Martin H Oberbarnscheidt ，Werner Held ，Jennifer McNiff ，Dhanpat Jain ，Thomas Höfer ，Warren D Shlomchik

Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity

IL-10通过代谢重编程终末耗竭的CD8+ T细胞来增强抗肿瘤免疫力。

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-021-00940-2

Yugang Guo #,Yu-Qing Xie #,Min Gao,Yang Zhao,Fabien Franco,Mathias Wenes,Imran Siddiqui,Alessio Bevilacqua,Haiping Wang,Hanshuo Yang,Bing Feng,Xin Xie,Catherine M Sabatel,Benjamin Tschumi,Amphun Chaiboonchoe,Yuxi Wang,Weimin Li,Weihua Xiao,Werner Held,Pedro Romero,Ping-Chih Ho,Li Tang

FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

FOLFIRI联合西妥昔单抗或贝伐珠单抗治疗晚期结直肠癌：FIRE-3随机临床试验的最终生存期和符合方案分析

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-020-01140-9

Heinemann, Volker; von Weikersthal, Ludwig Fischer; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Edin; Heintges, Tobias; Lerchenmüller, Christoph; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Moehler, Markus; Scheithauer, Werner; Held, Swantje; Miller-Phillips, Lisa; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian

Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation

中央记忆 CD8+ T 细胞来源于没有细胞毒性分化的干细胞样 Tcf7hi 效应细胞

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2020.09.005

Daniela Pais Ferreira, Joana Gomes Silva, Tania Wyss, Silvia A Fuertes Marraco, Léonardo Scarpellino, Mélanie Charmoy, Roeltje Maas, Imran Siddiqui, Li Tang, Johanna A Joyce, Mauro Delorenzi, Sanjiv A Luther, Daniel E Speiser, Werner Held

Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq

利用单细胞 RNA 测序解析 B16 黑色素瘤中肿瘤浸润 CD8 淋巴细胞的转录组图

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2020.1737369

Santiago J Carmona, Imran Siddiqui, Mariia Bilous, Werner Held, David Gfeller

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

具有干细胞样特性的肿瘤内 Tcf1+PD-1+CD8+ T 细胞在疫苗接种和检查点阻断免疫疗法反应中促进肿瘤控制

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2018.12.021

Imran Siddiqui, Karin Schaeuble, Vijaykumar Chennupati, Silvia A Fuertes Marraco, Sandra Calderon-Copete, Daniela Pais Ferreira, Santiago J Carmona, Leonardo Scarpellino, David Gfeller, Sylvain Pradervand, Sanjiv A Luther, Daniel E Speiser, Werner Held

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

Shp-2对于NK细胞中IL-15受体下游的ERK和代谢参与至关重要。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-019-09431-3

Charlène Niogret ，S M Shahjahan Miah ，Giorgia Rota ，Nicolas P Fonta ，Haiping Wang ，Werner Held ，Walter Birchmeier ，Veronica Sexl ，Wentian Yang ，Eric Vivier ，Ping-Chih Ho ，Laurent Brossay ，Greta Guarda

Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer

型干扰素/IRF7 轴引发乳腺癌化疗诱导的免疫休眠

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-018-0624-2

Qiang Lan, Sanam Peyvandi, Nathalie Duffey, Yu-Ting Huang, David Barras, Werner Held, François Richard, Mauro Delorenzi, Christos Sotiriou, Christine Desmedt, Girieca Lorusso, Curzio Rüegg0

The type 2 cytokine Fc-IL-4 revitalizes exhausted CD8+ T cells against cancer

2型细胞因子Fc-IL-4可激活耗竭的CD8+ T细胞，使其对抗癌症。

Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis

荧光报告基因微环境定位标记策略在实验性脑转移瘤中的应用研究

Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells

移植物抗宿主病是由靶组织中驻留的祖细胞样T细胞在局部维持的。

Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity

IL-10通过代谢重编程终末耗竭的CD8+ T细胞来增强抗肿瘤免疫力。

FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

FOLFIRI联合西妥昔单抗或贝伐珠单抗治疗晚期结直肠癌：FIRE-3随机临床试验的最终生存期和符合方案分析

Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation

中央记忆 CD8+ T 细胞来源于没有细胞毒性分化的干细胞样 Tcf7hi 效应细胞

Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq

利用单细胞 RNA 测序解析 B16 黑色素瘤中肿瘤浸润 CD8 淋巴细胞的转录组图

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

具有干细胞样特性的肿瘤内 Tcf1+PD-1+CD8+ T 细胞在疫苗接种和检查点阻断免疫疗法反应中促进肿瘤控制

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

Shp-2对于NK细胞中IL-15受体下游的ERK和代谢参与至关重要。

Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer

型干扰素/IRF7 轴引发乳腺癌化疗诱导的免疫休眠