日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deep learning-based H&E-derived risk scores in colorectal cancer: associations with tumour morphology, biology, and predicted drug response

基于深度学习的H&E染色结直肠癌风险评分:与肿瘤形态、生物学和预测药物反应的关联

Reitsam, Nic G; Jiang, Xiaofeng; Liang, Junhao; Grosser, Bianca; Grozdanov, Veselin; Loeffler, Chiara Ml; Gustav, Marco; Lenz, Tim; Muti, Hannah S; Carrero, Zunamys I; West, Nicholas P; Quirke, Philip; Foersch, Sebastian; Jesinghaus, Moritz; Müller, Wolfram; Yuan, Tanwei; Hoffmeister, Michael; Brenner, Hermann; Jonnagaddala, Jitendra; Hawkins, Nicholas J; Ward, Robyn L; Grabsch, Heike I; Märkl, Bruno; Kather, Jakob N

AI-powered immune profiling from histopathology slides for chemo-radiotherapy outcome prediction in rectal cancer: a study using clinical trial and real-world cohorts

利用人工智能技术从组织病理切片中进行免疫分析,预测直肠癌化疗放疗疗效:一项基于临床试验和真实世界队列的研究

Shen, Zhuoyan; Brand, Douglas; Simard, Mikaël; Levine, Adam P; Hindocha, Sumeet; Mistry, Talisa; Oukrif, Dahmane; Lopes, Andre; Begum, Rubina; West, Nicholas P; Zhang, Ying; Royle, Gary; Maughan, Tim S; Sebag-Montefiore, David; Hawkins, Maria A; Collins-Fekete, Charles-Antoine

Intranasal delivery of engineered anti-SARS-CoV-2 extracellular vesicles therapeutically represses lung infection and inflammation

经鼻内递送工程化抗SARS-CoV-2细胞外囊泡可有效抑制肺部感染和炎症。

Idris, Adi; Shrivastava, Surya; Gao, Wenqing; Supramaniam, Aroon; Tayyar, Yaman; West, Nicholas P; Kelly, Gabrielle; Acharya, Dhruba; McMillan, Nigel A J; Morris, Kevin V

Tumour-Infiltrating Lymphocytes, Tumour Cell Density, and Response to Neoadjuvant Short-Course Radiotherapy in Rectal Cancer: A Translational Sub-Study from the MRC CR07 Clinical Trial

肿瘤浸润淋巴细胞、肿瘤细胞密度和直肠癌新辅助短期放疗反应:MRC CR07 临床试验的转化子研究

Callaghan, Jonathan P; Jarrett, Ross; Westwood, Alice C; Laye, Jon; Quirke, Philip; Magee, Derek R; Bottomley, Daniel; Sebag-Montefiore, David; Thompson, Lindsay; Meade, Angela; Grabsch, Heike I; West, Nicholas P

Spatial Transcriptomics Reveals Novel Mechanisms Involved in Perineural Invasion in Pancreatic Ductal Adenocarcinomas

空间转录组学揭示胰腺导管腺癌神经周围浸润的新机制

Lakis, Vanessa; Chan, Noni L; Lyons, Ruth; Blackburn, Nicola; Nguyen, Tam Hong; Chang, Crystal; Masel, Andrew; West, Nicholas P; Boyle, Glen M; Patch, Ann-Marie; Gill, Anthony J; Nones, Katia

Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population

在老年人群中,使用鼻内 TLR2/6 激动剂启动黏膜病原体非特异性先天免疫

Mercuri, Francesca A; Zhuang, Aowen; McQuilten, Hayley A; Jarnicki, Andrew; O'Donoghue, Robert; O'Brien, Caitlin; Ciccotosto, Giuseppe D; Zhang, Ping; Demaison, Christophe; White, Scott; West, Nicholas P; Tal-Singer, Ruth; Anderson, Gary P

CT staging performance in an international trial of neoadjuvant chemotherapy for locally advanced colon cancer

CT分期在局部晚期结肠癌新辅助化疗国际试验中的表现

Platt, James R; Elliott, Faye; Handley, Kelly; Magill, Laura; Quirke, Philip; Seymour, Matthew T; West, Nicholas P; Morton, Dion; Seligmann, Jenny; Tolan, Damian J M

Characterization of PPE19 as a novel mediator of Mycobacterium tuberculosis-macrophage interactions

PPE19作为结核分枝杆菌-巨噬细胞相互作用的新型介质的特性研究

De Voss, Christopher J; Riek, Sean N; Stupar, Miljan; Tan, Lendl; Forde, Brian M; West, Nicholas P

A Ketol-Acid Reductoisomerase Inhibitor That Has Antituberculosis and Herbicidal Activity.

一种具有抗结核和除草活性的酮酸还原异构酶抑制剂

Lin Xin, Kurz Julia L, Li Yong-Hong, Wun Shun Jie, Lonhienne Thierry, McGeary Ross P, West Nicholas P, Schenk Gerhard, Wang Jian-Guo, Guddat Luke W

Deep-learning enabled combined measurement of tumour cell density and tumour infiltrating lymphocyte density as a prognostic biomarker in colorectal cancer

深度学习技术能够将肿瘤细胞密度和肿瘤浸润淋巴细胞密度联合测量,作为结直肠癌的预后生物标志物。

Westwood, Alice C; Wilson, Benjamin I; Laye, Jon; Grabsch, Heike I; Mueller, Wolfram; Magee, Derek R; Quirke, Phillip; West, Nicholas P