日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity

一种用于检测基孔肯雅病毒蛋白酶(nsP2)活性的强效荧光底物

Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo, Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A

A Robust Fluorogenic Substrate for Chikungunya Virus Protease (nsP2) Activity

一种用于检测基孔肯雅病毒蛋白酶 (nsP2) 活性的强效荧光底物

Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo, Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A

An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.

口服生物利用度高的 SARS-CoV-2 主蛋白酶抑制剂表现出更高的亲和力和更低的突变敏感性

Westberg Michael, Su Yichi, Zou Xinzhi, Huang Pinghan, Rustagi Arjun, Garhyan Jaishree, Patel Puja Bhavesh, Fernandez Daniel, Wu Yan, Hao Chenzhou, Lo Chieh-Wen, Karim Marwah, Ning Lin, Beck Aimee, Saenkham-Huntsinger Panatda, Tat Vivian, Drelich Aleksandra, Peng Bi-Hung, Einav Shirit, Tseng Chien-Te K, Blish Catherine, Lin Michael Z

Replication capacity and susceptibility of nirmatrelvir-resistant mutants to next-generation Mpro inhibitors in a SARS-CoV-2 replicon system

在SARS-CoV-2复制子系统中,耐尼马曲韦突变体的复制能力及其对新一代Mpro抑制剂的敏感性

Lo, Chieh-Wen; Kariv, Omri; Hao, Chenzhou; Gammeltoft, Karen Anbro; Bukh, Jens; Gottwein, Judith; Westberg, Michael; Lin, Michael Z; Einav, Shirit

A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3.

一种具有改进的单体性的红色荧光蛋白能够利用 ASAP3 进行比率电压成像

Kim Benjamin B, Wu Haodi, Hao Yukun A, Pan Michael, Chavarha Mariya, Zhao Yufeng, Westberg Michael, St-Pierre François, Wu Joseph C, Lin Michael Z