日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Harnessing endogenous anti-glycan antibodies using a novel, bifunctional immunotherapy to treat gram-negative bacterial infections.

利用新型双功能免疫疗法，发挥内源性抗聚糖抗体治疗革兰氏阴性菌感染

期刊:Journal of Immunology
影响因子:3.4
doi:10.1093/jimmun/vkaf055
Hairsine Bailey, Leire Emma, Rostam Hassan M, Kristian Sascha A, Rhodes Edward, Johnson Adam, Bushdyhan Matthew, Chapman David, Pickford Chris, Westby Mike, Bright Helen
免疫/内分泌
发表日期：2025
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Clonal analysis of HIV-1 genotype and function associated with virologic failure in treatment-experienced persons receiving maraviroc: Results from the MOTIVATE phase 3 randomized, placebo-controlled trials

对接受马拉维罗治疗的既往治疗患者中与病毒学失败相关的 HIV-1 基因型和功能进行克隆分析：来自 MOTIVATE 3 期随机、安慰剂对照试验的结果

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0204099
Lewis, Marilyn; Mori, Julie; Toma, Jonathan; Mosley, Mike; Huang, Wei; Simpson, Paul; Mansfield, Roy; Craig, Charles; van der Ryst, Elna; Robertson, David L; Whitcomb, Jeannette M; Westby, Mike
HIV
微生物学
发表日期：2018
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Retargeting pre-existing human antibodies to a bacterial pathogen with an alpha-Gal conjugated aptamer

利用α-半乳糖偶联适体将预先存在的针对细菌病原体的人类抗体重新靶向

期刊:Journal of Molecular Medicine-Jmm
影响因子:4.2
doi:10.1007/s00109-015-1280-4
Kristian, Sascha A; Hwang, John H; Hall, Bradley; Leire, Emma; Iacomini, John; Old, Robert; Galili, Uri; Roberts, Charles; Mullis, Kary B; Westby, Mike; Nizet, Victor
微生物学
发表日期：2015
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Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor

表征与 R5 嗜性马拉维罗克耐药性相关的多种突变途径：利用药物结合的 CCR5 辅助受体的 HIV-1

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.01384-15
Jiang, Xiaowei; Feyertag, Felix; Meehan, Conor J; McCormack, Grace P; Travers, Simon A; Craig, Charles; Westby, Mike; Lewis, Marilyn; Robertson, David L
HIV
信号转导
CCR5
微生物学
发表日期：2015
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A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

尽管耐药水平存在差异且缺乏常见的gp120耐药突变，但临床上HIV-1对CCR5拮抗剂马拉维罗克产生耐药性的常见机制

期刊:Retrovirology
影响因子:3.9
doi:10.1186/1742-4690-10-43
Roche, Michael; Salimi, Hamid; Duncan, Renee; Wilkinson, Brendan L; Chikere, Kelechi; Moore, Miranda S; Webb, Nicholas E; Zappi, Helena; Sterjovski, Jasminka; Flynn, Jacqueline K; Ellett, Anne; Gray, Lachlan R; Lee, Benhur; Jubb, Becky; Westby, Mike; Ramsland, Paul A; Lewin, Sharon R; Payne, Richard J; Churchill, Melissa J; Gorry, Paul R
HIV
CCR5
微生物学
发表日期：2013
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Knockdown of USP18 increases α 2a interferon signaling and induction of interferon-stimulating genes but does not increase antiviral activity in Huh7 cells

敲除 USP18 可增强 α2a 干扰素信号传导和干扰素刺激基因的诱导，但不会增强 Huh7 细胞的抗病毒活性。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00644-11
Murray, E J; Burden, Frances; Horscroft, Nigel; Smith-Burchnell, Caroline; Westby, Mike
微生物学
信号转导
细胞生物学
SP1
发表日期：2011
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HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

体外实验表明，HIV-1病毒株本身就具有低水平的能力，能够利用与MVC结合的CCR5进入细胞，从而更容易对马拉维罗克（MVC）和其他CCR5拮抗剂产生耐药性。

期刊:Retrovirology
影响因子:3.9
doi:10.1186/1742-4690-8-89
Roche, Michael; Jakobsen, Martin R; Ellett, Anne; Salimiseyedabad, Hamid; Jubb, Becky; Westby, Mike; Lee, Benhur; Lewin, Sharon R; Churchill, Melissa J; Gorry, Paul R
HIV
细胞生物学
CCR5
微生物学
发表日期：2011
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Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action

靶向丙型肝炎病毒编码的NS5A的小分子可引起其靶点的亚细胞重分布：对化合物作用机制的深入理解

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.00215-11
Targett-Adams, Paul; Graham, Emily J S; Middleton, Jenny; Palmer, Amy; Shaw, Stephen M; Lavender, Helen; Brain, Philip; Tran, Thien Duc; Jones, Lyn H; Wakenhut, Florian; Stammen, Blanda; Pryde, David; Pickford, Chris; Westby, Mike
微生物学
细胞生物学
肝炎
发表日期：2011
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Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.

勒西韦林是一种非核苷类逆转录酶抑制剂，对耐药性人类免疫缺陷病毒1型具有活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01455-09
Corbau Romuald, Mori Julie, Phillips Chris, Fishburn Lesley, Martin Alex, Mowbray Charles, Panton Wendy, Smith-Burchnell Caroline, Thornberry Adele, Ringrose Heather, Knöchel Thorsten, Irving Steve, Westby Mike, Wood Anthony, Perros Manos
其它
Human
发表日期：2010
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Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease

利用高灵敏度链特异性定量PCR技术鉴定呼吸道合胞病毒疾病小鼠模型中的异常复制

期刊:Virology Journal
影响因子:3.8
doi:10.1186/1743-422X-7-250
Bannister, Richard; Rodrigues, Deborah; Murray, Edward J; Laxton, Carl; Westby, Mike; Bright, Helen
微生物学
发表日期：2010
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