日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

硒蛋白O促进黑色素瘤转移并调节线粒体复合物II活性

Luiza Martins Nascentes Melo, Marie Sabatier, Vijayashree Ramesh, Krystina J Szylo, Cameron S Fraser, Alex Pon, Evann C Mitchell, Kelly A Servage, Gabriele Allies, Isa V Westedt, Feyza Cansiz, Jonathan Krystkiewicz, Andrea Kutritz, Dirk Schadendorf, Sean J Morrison, Jessalyn M Ubellacker #, Anju Sre

Infrared spectroscopy reveals metal-independent carbonic anhydrase activity in crotonyl-CoA carboxylase/reductase

红外光谱揭示了巴豆酰辅酶A羧化酶/还原酶中不依赖于金属的碳酸酐酶活性

Gomez, Aharon; Tinzl, Matthias; Stoffel, Gabriele; Westedt, Hendrik; Grubmüller, Helmut; Erb, Tobias J; Vöhringer-Martinez, Esteban; Stripp, Sven T

Transformation of ABT-199 Nanocrystal Suspensions into a Redispersible Drug Product-Impact of Vacuum Drum Drying, Spray Drying and Tableting on Re-Nanodispersibility

将ABT-199纳米晶悬浮液转化为可再分散药物制剂——真空滚筒干燥、喷雾干燥和压片对再纳米分散性的影响

Schönfeld, Barbara; Sundermann, Julius; Keller, Benjamin-Luca; Westedt, Ulrich; Heinzerling, Oliver

Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma

HSD11B1介导的糖皮质激素激活会限制黑色素瘤中T细胞驱动的干扰素信号传导和对PD-1阻断的反应。

Luiza Martins Nascentes Melo # ,Dayana Herrera-Rios # ,Daniel Hinze # ,Stefanie Löffek # ,Irem Oezel ,Roberta Turiello ,Juliane Klein ,Sonia Leonardelli ,Isa-Vanessa Westedt ,Yahya Al-Matary ,Sara Egea-Rodriguez ,Alexandra Brenzel ,Maja Bau ,Antje Sucker ,Eva Hadaschik ,Florian Wirsdörfer ,Helmut Hanenberg ,Niklas Uhlenbrock ,Daniel Rauh ,Joanna Poźniak ,Florian Rambow ,Jean-Christophe Marine ,Maike Effern ,Nicole Glodde ,Dirk Schadendorf ,Jadwiga Jablonska ,Michael Hölzel ,Iris Helfrich

Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models

通过将双相溶出数据引入PBPK模型实现更高级的体内预测

Denninger, Alexander; Becker, Tim; Westedt, Ulrich; Wagner, Karl G

Compression Modulus and Apparent Density of Polymeric Excipients during Compression-Impact on Tabletability

压缩过程中聚合物辅料的压缩模量和表观密度对片剂成型性的影响

Schönfeld, Barbara V; Westedt, Ulrich; Wagner, Karl G

Shared IVIVR for Five Commercial Enabling Formulations Using the BiPHa+ Biphasic Dissolution Assay

利用 BiPHa+ 双相溶出试验对五种商业化制剂进行共享的体外-体内-虚拟现实(IVIVR)研究

Denninger, Alexander; Westedt, Ulrich; Wagner, Karl G

A Rational Design of a Biphasic DissolutionSetup-Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion

双相溶出装置的合理设计——利托那韦热熔挤出无定形固体分散体的生物相关动力学建模

Denninger, Alexander; Westedt, Ulrich; Rosenberg, Jörg; Wagner, Karl G

Pseudomonas HopU1 modulates plant immune receptor levels by blocking the interaction of their mRNAs with GRP7

假单胞菌HopU1通过阻断植物免疫受体mRNA与GRP7的相互作用来调节植物免疫受体水平。

Nicaise, Valerie; Joe, Anna; Jeong, Byeong-ryool; Korneli, Christin; Boutrot, Freddy; Westedt, Isa; Staiger, Dorothee; Alfano, James R; Zipfel, Cyril

The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility

难溶性 ABT-102 的无定形固体分散体在水性介质中形成纳米/微粒结构:对溶解度的影响

Kerstin J Frank, Ulrich Westedt, Karin M Rosenblatt, Peter Hölig, Jörg Rosenberg, Markus Mägerlein, Gert Fricker, Martin Brandl