日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD4 receptor diversity in chimpanzees protects against SIV infection

黑猩猩的 CD4 受体多样性可预防 SIV 感染

Frederic Bibollet-Ruche, Ronnie M Russell, Weimin Liu, Guillaume B E Stewart-Jones, Scott Sherrill-Mix, Yingying Li, Gerald H Learn, Andrew G Smith, Marcos V P Gondim, Lindsey J Plenderleith, Julie M Decker, Juliet L Easlick, Katherine S Wetzel, Ronald G Collman, Shilei Ding, Andrés Finzi, Ahidjo Ay

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease

突变分析表明,淀粉样蛋白原纤维是亨廷顿病中的毒性物质。

Drombosky, Kenneth W; Rode, Sascha; Kodali, Ravi; Jacob, Tija C; Palladino, Michael J; Wetzel, Ronald

Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation

利用潜在β-发夹结构进行骨架工程设计,以抑制多聚谷氨酰胺淀粉样蛋白的形成

Kar, Karunakar; Baker, Matthew A; Lengyel, George A; Hoop, Cody L; Kodali, Ravindra; Byeon, In-Ja; Horne, W Seth; van der Wel, Patrick C A; Wetzel, Ronald

Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway

由Aβ C末端介导的快速α-寡聚体形成启动了淀粉样蛋白组装途径。

Misra, Pinaki; Kodali, Ravindra; Chemuru, Saketh; Kar, Karunakar; Wetzel, Ronald

Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.

突变亨廷顿蛋白外显子1的折叠景观:可扩散的多聚体、寡聚体和原纤维,以及未检测到的单体

Sahoo Bankanidhi, Arduini Irene, Drombosky Kenneth W, Kodali Ravindra, Sanders Laurie H, Greenamyre J Timothy, Wetzel Ronald

Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses

Cercopithecini 族系链蛋白与其慢病毒之间的共同进化动力学

Junko S Takeuchi, Fengrong Ren, Rokusuke Yoshikawa, Eri Yamada, Yusuke Nakano, Tomoko Kobayashi, Kenta Matsuda, Taisuke Izumi, Naoko Misawa, Yuta Shintaku, Katherine S Wetzel, Ronald G Collman, Hiroshi Tanaka, Vanessa M Hirsch, Yoshio Koyanagi, Kei Sato

D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells

D-聚谷氨酰胺淀粉样蛋白募集L-聚谷氨酰胺单体并杀死细胞。

Kar, Karunakar; Arduini, Irene; Drombosky, Kenneth W; van der Wel, Patrick C A; Wetzel, Ronald

Biophysical underpinnings of the repeat length dependence of polyglutamine amyloid formation

多聚谷氨酰胺淀粉样蛋白形成对重复序列长度依赖性的生物物理学基础

Landrum, Elizabeth; Wetzel, Ronald

Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B

利用添加C端赖氨酸(随后用羧肽酶B去除)改进疏水性Aβ肽的化学合成方法

Chemuru, Saketh; Kodali, Ravindra; Wetzel, Ronald

Aggregation behavior of chemically synthesized, full-length huntingtin exon1

化学合成的全长亨廷顿蛋白外显子1的聚集行为

Sahoo, Bankanidhi; Singer, David; Kodali, Ravindra; Zuchner, Thole; Wetzel, Ronald