日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Phase 2a Trial of Myeloperoxidase Inhibitor Mitiperstat in Non-Cirrhotic Metabolic Dysfunction-Associated Steatohepatitis

一项针对非肝硬化代谢功能障碍相关脂肪性肝炎的髓过氧化物酶抑制剂Mitiperstat的2a期试验

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.70406
Armisen, Javier; Flor, Armando; Eriksson, John; Nelander, Karin; Bhattacharya, Chandrali S; Sunnåker, Mikael; Carter, Debra; Trebski, Monika; Gårdmark, Emma; Aurell, Malin; Whatling, Carl; Challis, Benjamin; Vespasiani-Gentilucci, Umberto
肝炎
肝硬化
代谢
发表日期：2025
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Safety, Tolerability, and Pharmacodynamics of AZD3366 (Optimized Human CD39L3 Apyrase) Alone and in Combination With Ticagrelor and Acetylsalicylic Acid: A Phase 1, Randomized, Placebo-Controlled Study

AZD3366（优化的人CD39L3腺苷三磷酸酶）单药及联合替格瑞洛和乙酰水杨酸的安全性、耐受性和药效学：一项1期随机、安慰剂对照研究

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.123.033985
Kardassis, Dimitris; Egnell, Ann-Charlotte; Åstrand, Magnus; Daniels, Samuel J; Whatling, Carl; Fjellström, Ola; Gabrielsen, Anders
CD3
Human
CD39
发表日期：2024
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Rationale and design of ENDEAVOR: A sequential phase 2b-3 randomized clinical trial to evaluate the effect of myeloperoxidase inhibition on symptoms and exercise capacity in heart failure with preserved or mildly reduced ejection fraction

ENDEAVOR 研究的原理和设计：一项序贯的 2b-3 期随机临床试验，旨在评估髓过氧化物酶抑制剂对射血分数保留或轻度降低的心力衰竭患者的症状和运动能力的影响

期刊:European Journal of Heart Failure
影响因子:10.8
doi:10.1002/ejhf.2977
Lund, Lars H; Lam, Carolyn S P; Pizzato, Patricia E; Gabrielsen, Anders; Michaëlsson, Erik; Nelander, Karin; Ericsson, Hans; Holden, Julie; Folkvaljon, Folke; Mattsson, Andrea; Collén, Anna; Aurell, Malin; Whatling, Carl; Baldus, Stephan; Drelich, Grzegorz; Goudev, Assen; Merkely, Béla; Bergh, Niklas; Shah, Sanjiv J
心力衰竭
心血管
发表日期：2023
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Modelling clinical narrative as computable knowledge: The NICE computable implementation guidance project

将临床叙事建模为可计算知识：NICE 可计算实施指南项目

期刊:
影响因子:
doi:10.1002/lrh2.10394
Scott, Philip; Heigl, Michaela; McCay, Charles; Shepperdson, Polly; Lima-Walton, Elia; Andrikopoulou, Elisavet; Brunnhuber, Klara; Cornelius, Gary; Faulding, Susan; McAlister, Ben; Rowark, Shaun; South, Matthew; Thomas, Mark R; Whatling, Justin; Williams, John; Wyatt, Jeremy C; Greaves, Felix
发表日期：2023
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Knee osteoarthritis alters peri-articular knee muscle strategies during gait

膝骨关节炎会改变步态过程中膝关节周围肌肉的运动策略

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0262798
Ghazwan, Aseel; Wilson, Chris; Holt, Cathy A; Whatling, Gemma M
关节炎
发表日期：2022
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Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans

新型病变转录特征可区分约克郡猪和人类的糖尿病相关动脉粥样硬化与非糖尿病相关动脉粥样硬化

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.121.315896
Haemmig, Stefan; Hashemi Gheinani, Ali; Zaromytidou, Marina; Siasos, Gerasimos; Coskun, Ahmet Umit; Cormier, Michelle A; Gross, David A; Wara, A K M Khyrul; Antoniadis, Antonios P; Sun, Xinghui; Sukhova, Galina K; Welt, Fred G P; Andreou, Ioannis; Whatling, Carl; Gan, Li-Ming; Wikström, Johannes; Edelman, Elazer R; Libby, Peter; Stone, Peter H; Feinberg, Mark W
心血管
代谢
Human
糖尿病
动脉粥样硬化
发表日期：2021
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Design of FLAIR: a Phase 2b Study of the 5-Lipoxygenase Activating Protein Inhibitor AZD5718 in Patients With Proteinuric CKD

FLAIR 研究设计：一项针对蛋白尿性慢性肾脏病患者的 5-脂氧合酶激活蛋白抑制剂 AZD5718 的 IIb 期研究

期刊:Kidney International Reports
影响因子:5.7
doi:10.1016/j.ekir.2021.08.018
Heerspink, Hiddo J L; Law, Gordon; Psachoulia, Konstantina; Connolly, Kathleen; Whatling, Carl; Ericsson, Hans; Knöchel, Jane; Lindstedt, Eva-Lotte; MacPhee, Iain
发表日期：2021
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Early Clinical Experience With AZD4831, A Novel Myeloperoxidase Inhibitor, Developed for Patients With Heart Failure With Preserved Ejection Fraction

AZD4831（一种新型髓过氧化物酶抑制剂，专为射血分数保留型心力衰竭患者开发）的早期临床经验

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.12859
Nelander, Karin; Lagerstrom-Fermer, Maria; Amilon, Carl; Michaëlsson, Erik; Heijer, Maria; Kjaer, Magnus; Russell, Muir; Han, David; Lindstedt, Eva-Lotte; Whatling, Carl; Gan, Li-Ming; Ericsson, Hans
心力衰竭
心血管
发表日期：2021
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High tibial osteotomy results in improved frontal plane knee moments, gait patterns and patient-reported outcomes

高位胫骨截骨术可改善膝关节额状面力矩、步态模式和患者自述疗效。

期刊:Knee Surgery Sports Traumatology Arthroscopy
影响因子:5
doi:10.1007/s00167-019-05644-7
Whatling, Gemma M; Biggs, Paul R; Elson, David W; Metcalfe, Andrew; Wilson, Chris; Holt, Cathy
发表日期：2020
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The relationship between alignment, function and loading in total knee replacement: In-vivo analysis of a unique patient population

全膝关节置换术中对线、功能和负荷之间的关系：一项针对特定患者群体的体内分析

期刊:Journal of Biomechanics
影响因子:2.4
doi:10.1016/j.jbiomech.2020.110042
Williams, David; Metcalfe, Andrew; Madete, June; Whatling, Gemma; Kempshall, Peter; Forster, Mark; Lyons, Kathleen; Holt, Cathy
发表日期：2020
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