日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Computational design of dynamic biosensors for emerging synthetic opioids

新型合成阿片类药物动态生物传感器的计算设计

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67994-w
Leonard, Alison C; Lenert-Mondou, Chase; Chayer, Rachel; Swift, Samuel; Baumer, Zachary T; Delaney, Ryan; Friedman, Anika J; Robertson, Nicholas R; Seder, Norman; Wells, Jordan; Whitmore, Lindsey M; Cutler, Sean R; Shirts, Michael R; Wheeldon, Ian; Whitehead, Timothy A
发表日期：2026
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Protein engineering of a genetically encoded biosensor for wastewater detection of profen NSAIDs

利用基因编码生物传感器进行蛋白质工程改造，用于检测废水中的丙芬类非甾体抗炎药

期刊:
影响因子:
doi:10.64898/2026.01.14.699353
Davis, Zoë; Tian, Hao; Wheeldon, Ian; Cutler, Sean R; Whitehead, Timothy A
发表日期：2026
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Kingdom-wide CRISPR guide design with ALLEGRO.

使用 ALLEGRO 进行全王国范围的 CRISPR 指南设计

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf783
Mohseni Amirsadra, Nia Reyhane Ghorbani, Tafrishi Aida, López Mario León, Liu Xin-Zhan, Stajich Jason E, Lonardi Stefano, Wheeldon Ian
发表日期：2025
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Synthesis of large single-transcript pathways from oligonucleotide pools: Design of STARBURST, an autobioluminescent reporter

利用寡核苷酸库合成大型单转录本通路：STARBURST（一种自发光报告基因）的设计

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2508109122
Dvir, Gony; Xing, Zenan; Beldman, Irina; Rivera, Andrés; Wheeldon, Ian; Cutler, Sean R
信号转导
STAR
发表日期：2025
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Unusually broad-spectrum small-molecule sensing using a single protein scaffold

利用单个蛋白质支架实现异常宽光谱的小分子传感

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2519924122
Tian, Hao; Beltrán, Jesús; George, Wesley; Lenert-Mondou, Chase; Seder, Norman; Davis, Zoe I; Swift, Samuel D; Girke, Thomas; Whitehead, Timothy A; Wheeldon, Ian; Cutler, Sean R
发表日期：2025
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PYR1 Biosensor-Driven Genome-Wide CRISPR Screens for Improved Monoterpene Production in Kluyveromyces marxianus.

利用 PYR1 生物传感器驱动的全基因组 CRISPR 筛选提高克鲁维酵母单萜的产量

期刊:ACS Synthetic Biology
影响因子:3.9
doi:10.1021/acssynbio.4c00797
Robertson Nicholas R, Lenert-Mondou Chase, Leonard Alison C, Tafrishi Aida, Carrera Stephanie, Lee Sangcheon, Aguilar Yuna, Sanchez Zamora Leonardo, Nguyen Trinity, Beltrán Jesús, Li Mengwan, Cutler Sean R, Whitehead Timothy A, Wheeldon Ian
其它
发表日期：2025
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Advances in CRISPR-enabled genome-wide screens in yeast

酵母中 CRISPR 基因组筛选的进展

期刊:FEMS Yeast Research
影响因子:2.7
doi:10.1093/femsyr/foaf013
Robertson, Nicholas R; Lee, Sangcheon; Tafrishi, Aida; Wheeldon, Ian
发表日期：2025
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Expressing intrinsically-disordered tardigrade proteins has positive effects on acute but not chronic stress tolerance in Saccharomyces cerevisiae

表达内在无序的缓步动物蛋白对酿酒酵母的急性应激耐受性有积极影响，但对慢性应激耐受性没有影响。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0325682
León López, Mario; Wheeldon, Ian; Morgan, Joshua T
发表日期：2025
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Computational design of dynamic biosensors for emerging synthetic opioids

新型合成阿片类药物动态生物传感器的计算设计

期刊:
影响因子:
doi:10.1101/2025.05.15.654300
Leonard, Alison C; Lenert-Mondou, Chase; Chayer, Rachel; Swift, Samuel; Baumer, Zachary T; Delaney, Ryan; Friedman, Anika J; Robertson, Nicholas R; Seder, Norman; Wells, Jordan; Whitmore, Lindsey M; Cutler, Sean R; Shirts, Michael R; Wheeldon, Ian; Whitehead, Timothy A
发表日期：2025
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Balanced Training Sets Improve Deep Learning-Based Prediction of CRISPR sgRNA Activity

平衡训练集可提高基于深度学习的 CRISPR sgRNA 活性预测精度。

期刊:ACS Synthetic Biology
影响因子:3.9
doi:10.1021/acssynbio.4c00542
Trivedi, Varun; Mohseni, Amirsadra; Lonardi, Stefano; Wheeldon, Ian
发表日期：2024
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