日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of the seven critical residues that control ZIKV-DENV cross-reactivity to engineer a non-cross-reactive ZIKV vaccine

鉴定控制寨卡病毒-登革病毒交叉反应的七个关键残基,以设计一种无交叉反应的寨卡病毒疫苗

Grinyo-Escuer, Ariadna; Reddy, Srikar; Chenine, Agnes L; Whitbeck, J Charles; Jacobsen, Sonya; Sheetz, Allison; Doolan, Kyle; Norden, Diana M; Frey, Nolan; Holtsberg, Frederick W; Aman, M Javad; Fink, Katja; Diamond, Michael S; Schieffelin, John S; Crowe, James E Jr; Davidson, Edgar; Doranz, Benjamin J

Using Antibodies and Mutants To Localize the Presumptive gH/gL Binding Site on Herpes Simplex Virus gD

利用抗体和突变体定位单纯疱疹病毒gD上的假定gH/gL结合位点

Atanasiu, Doina; Saw, Wan Ting; Lazear, Eric; Whitbeck, J Charles; Cairns, Tina M; Lou, Huan; Eisenberg, Roselyn J; Cohen, Gary H

Functional fluorescent protein insertions in herpes simplex virus gB report on gB conformation before and after execution of membrane fusion

单纯疱疹病毒gB蛋白中的功能性荧光蛋白插入可以反映膜融合前后gB蛋白的构象变化。

Gallagher, John R; Atanasiu, Doina; Saw, Wan Ting; Paradisgarten, Matthew J; Whitbeck, J Charles; Eisenberg, Roselyn J; Cohen, Gary H

Regulation of herpes simplex virus gB-induced cell-cell fusion by mutant forms of gH/gL in the absence of gD and cellular receptors

在缺乏gD和细胞受体的情况下,gH/gL突变体对单纯疱疹病毒gB诱导的细胞融合的调控

Atanasiu, Doina; Cairns, Tina M; Whitbeck, J Charles; Saw, Wan Ting; Rao, Samhita; Eisenberg, Roselyn J; Cohen, Gary H

The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction

疱疹病毒融合糖蛋白B-双层复合物的结构揭示了蛋白质-膜相互作用和侧向蛋白质-蛋白质相互作用。

Maurer, Ulrike E; Zeev-Ben-Mordehai, Tzviya; Pandurangan, Arun Prasad; Cairns, Tina M; Hannah, Brian P; Whitbeck, J Charles; Eisenberg, Roselyn J; Cohen, Gary H; Topf, Maya; Huiskonen, Juha T; Grünewald, Kay

Capturing the herpes simplex virus core fusion complex (gB-gH/gL) in an acidic environment

在酸性环境下捕获单纯疱疹病毒核心融合复合物(gB-gH/gL)

Cairns, Tina M; Whitbeck, J Charles; Lou, Huan; Heldwein, Ekaterina E; Chowdary, Tirumala K; Eisenberg, Roselyn J; Cohen, Gary H

Bimolecular complementation defines functional regions of Herpes simplex virus gB that are involved with gH/gL as a necessary step leading to cell fusion

双分子互补作用确定了单纯疱疹病毒gB的功能区域,这些区域与gH/gL相互作用,是细胞融合的必要步骤。

Atanasiu, Doina; Whitbeck, J Charles; de Leon, Manuel Ponce; Lou, Huan; Hannah, Brian P; Cohen, Gary H; Eisenberg, Roselyn J

Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops

单纯疱疹病毒糖蛋白B通过其融合环与靶膜结合。

Hannah, Brian P; Cairns, Tina M; Bender, Florent C; Whitbeck, J Charles; Lou, Huan; Eisenberg, Roselyn J; Cohen, Gary H

Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans

痘苗病毒L1蛋白与细胞表面结合,并独立于糖胺聚糖阻断病毒入侵。

Foo, Chwan Hong; Lou, Huan; Whitbeck, J Charles; Ponce-de-León, Manuel; Atanasiu, Doina; Eisenberg, Roselyn J; Cohen, Gary H

Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses.

针对疱疹病毒入侵介质的抗原可增强原发性适应性免疫反应

Lasaro Marcio O, Tatsis Nia, Hensley Scott E, Whitbeck J Charles, Lin Shih-Wen, Rux John J, Wherry E John, Cohen Gary H, Eisenberg Roselyn J, Ertl Hildegund C