Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH)
疟原虫体内前药的激活是由一种输入的红细胞酯酶——酰基肽水解酶(APEH)介导的。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2417682122
Sundararaman, Sesh A; Miller, Justin J; Daley, Ellora C; O'Brien, Kelsey A; Kasak, Paulina; Daniels, Abigail M; Edwards, Rachel L; Heidel, Kenneth M; Bague, Darean A; Wilson, Madeleine A; Koelper, Andrew J; Kourtoglou, Elexi C; White, Alex D; August, Sloan A; Apple, Georgia A; Rouamba, Regis W; Durand, Anthony J; Esteb, John J; Muller, Florian L; Johnson, R Jeremy; Hoops, Geoffrey C; Dowd, Cynthia S; Odom John, Audrey R