Whitfield Michael L相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis

RUNX1在真皮成纤维细胞的一个亚群中表达，并且与系统性硬化症的疾病严重程度相关。

期刊:Annals of the Rheumatic Diseases

影响因子:20.6

doi:10.1016/j.ard.2025.10.033

Parvizi, Rezvan; Gong, Zhiyun; Jarnagin, Helen C; Toledo, Diana M; Abel, Tamar R; Popovich, Dillon; Morrisson, Madeline J; Wood, Tammara A; Shenk, Sasha; Sarkar, Mrinal K; Plazyo, Olesya; Dey, Poulami; Coon, Anthony; Erba, Jake M; Tsoi, Lam C; Tsou, Pei-Suen; Hinchcliff, Monique E; Khanna, Dinesh; Garlick, Jonathan A; Gudjonsson, Johann E; Pioli, Patricia A; Whitfield, Michael L

成纤维细胞

系统性硬化症

细胞生物学

免疫/内分泌

发表日期：2026

文献求助收藏

Multimodal analyses of early, untreated systemic sclerosis skin identify a proinflammatory vascular niche of macrophage-fibroblast signaling.

对早期未经治疗的系统性硬化症皮肤进行多模态分析，发现巨噬细胞-成纤维细胞信号传导的促炎血管微环境。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.198954

Jarnagin Helen C, Parvizi Rezvan, Gong Zhiyun, Gedert Rosemary, Xing Xianying, Tsoi Lam Alex C, Bogle Rachael, Morrisson Madeline J, Perreard Laurent, Pioli Patricia A, Kolling Fred 4th, Gudjonsson Johann E, Khanna Dinesh, Whitfield Michael L

系统性硬化症

细胞生物学

成纤维细胞

发表日期：2026

文献求助收藏

Mycophenolate mofetil directly modulates myeloid viability and pro-fibrotic activation of human macrophages.

吗替麦考酚酯直接调节髓系细胞活力和人类巨噬细胞的促纤维化活化

期刊:Rheumatology

影响因子:4.4

doi:10.1093/rheumatology/keae517

Morris Emily A, Parvizi Rezvan, Orzechowski Nicole M, Whitfield Michael L, Pioli Patricia A

细胞生物学

发表日期：2025

文献求助收藏

Geographic Clustering of Systemic Sclerosis in Areas of Environmental Pollution

环境污染地区系统性硬化症的地理聚集性

期刊:Arthritis Care & Research

影响因子:3.3

doi:10.1002/acr.25504

Kosarek, Noelle N; Romano, Megan E; Moen, Erika L; Simms, Robert W; Erickson, Ashleigh; Khanna, Dinesh; Pioli, Patricia A; Whitfield, Michael L

系统性硬化症

免疫/内分泌

发表日期：2025

文献求助收藏

Anti-CD206 CAR T Cell Treatment Restores Fibrosis-Induced Loss of Dermal White Adipose Tissue

抗CD206 CAR T细胞疗法可恢复纤维化引起的真皮白色脂肪组织丢失

doi:10.1101/2025.10.16.682860

Park, Chanhyuk; Mohamed, Asmaa O; Jarnagin, Helen C; Bhandari, Rajan; Gunn, Jason; Murad-Mabaera, Joana; Kosarek, Noelle N; Kolling, Fred W; Wilkins, Owen M; Huang, Yina H; Whitfield, Michael L; Pioli, Patricia A

免疫/内分泌

细胞生物学

发表日期：2025

文献求助收藏

Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents

通过 CREB1/EGR1 轴在自组装人类皮肤等效物中实现系统性硬化症成纤维细胞的单细胞表观基因组失调

doi:10.1101/2024.03.22.586316

Abel, Tamar R; Kosarek, Noelle N; Parvizi, Rezvan; Jarnagin, Helen; Torres, Gretel M; Bhandari, Rajan; Huang, Mengqi; Toledo, Diana M; Smith, Avi; Popovich, Dillon; Mariani, Michael P; Yang, Heetaek; Wood, Tammara; Garlick, Jonathan; Pioli, Patricia A; Whitfield, Michael L

成纤维细胞

细胞生物学

免疫/内分泌

系统性硬化症

发表日期：2024

文献求助收藏

Senescent Cells Accumulate in Systemic Sclerosis Skin

系统性硬化症皮肤中衰老细胞的积累

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2022.09.652

Shi, Bo; Tsou, Pei-Suen; Ma, Feiyang; Mariani, Michael P; Mattichak, Megan N; LeBrasseur, Nathan K; Chini, Eduardo N; Lafyatis, Robert; Khanna, Dinesh; Whitfield, Michael L; Gudjonsson, Johann E; Varga, John

细胞生物学

系统性硬化症

免疫/内分泌

发表日期：2023

文献求助收藏

Human dermal fibroblast-derived exosomes induce macrophage activation in systemic sclerosis

人真皮成纤维细胞来源的外泌体诱导系统性硬化症中的巨噬细胞活化

期刊:Rheumatology

影响因子:4.4

doi:10.1093/rheumatology/keac453

Bhandari, Rajan; Yang, Heetaek; Kosarek, Noelle N; Smith, Avi E; Garlick, Jonathan A; Hinchcliff, Monique; Whitfield, Michael L; Pioli, Patricia A

成纤维细胞

系统性硬化症

细胞生物学

免疫/内分泌

发表日期：2023

文献求助收藏

Clinical and Molecular Findings After Autologous Stem Cell Transplantation or Cyclophosphamide for Scleroderma: Handling Missing Longitudinal Data

自体干细胞移植或环磷酰胺治疗硬皮病后的临床和分子学发现：缺失纵向数据的处理

期刊:Arthritis Care & Research

影响因子:3.3

doi:10.1002/acr.24785

Keyes-Elstein, Lynette; Pinckney, Ashley; Goldmuntz, Ellen; Welch, Beverly; Franks, Jennifer M; Martyanov, Viktor; Wood, Tammara A; Crofford, Leslie; Mayes, Maureen; McSweeney, Peter; Nash, Richard; Georges, George; Csuka, M E; Simms, Robert; Furst, Daniel; Khanna, Dinesh; Clair, E William St; Whitfield, Michael L; Sullivan, Keith M

细胞生物学

发育与干细胞

系统性硬化症

发表日期：2023

文献求助收藏

CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma

CDDO-甲酯抑制BRAF抑制剂耐药性并重塑BRAF突变型黑色素瘤的髓系细胞区室

doi:10.1101/2023.08.01.551524

Torres, Gretel M; Jarnagin, Helen C; Park, Chanhyuk; Yang, Heetaek; Kosarek, Noelle N; Bhandari, Rajan; Wang, Chen-Yu; Kolling, Fred W; Whitfield, Michael L; Turk, Mary Jo; Liby, Karen T; Pioli, Patricia A

细胞生物学

发表日期：2023

文献求助收藏