Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS
在ALS敲入Sod1突变小鼠模型中,胆固醇合成途径上调,神经退行性变程度有限。
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doi:10.1101/2023.05.05.539444
Dominov, Janice A; Madigan, Laura A; Whitt, Joshua P; Rademacher, Katerina L; Webster, Kristin M; Zhang, Hesheng; Banno, Haruhiko; Tang, Siqi; Zhang, Yifan; Wightman, Nicholas; Shychuck, Emma M; Page, John; Weiss, Alexandra; Kelly, Karen; Kucukural, Alper; Brodsky, Michael H; Jaworski, Alexander; Fallon, Justin R; Lipscombe, Diane; Brown, Robert H