日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Functional assembly of the Qc-SNARE with Sec18 and Sec17 on membranes

Qc-SNARE 与 Sec18 和 Sec17 在膜上的功能性组装

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E25-10-0474
Orr, Amy; Lopes, Karina; O'Dwyer, Jerry; Wickner, William
发表日期：2026
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SNARE disassembly requires Sec18/NSF side loading

SNARE 拆卸需要 Sec18/NSF 侧向加载

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-025-01590-w
Khan, Yousuf A; White, K Ian; Pfuetzner, Richard A; Singal, Bharti; Esquivies, Luis; Mckenzie, Garvey; Liu, Fang; DeLong, Katherine; Choi, Ucheor B; Montabana, Elizabeth; Mclaughlin, Theresa; Wickner, William T; Brunger, Axel T
NSF
发表日期：2025
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Sec18 ATP hydrolysis selectively releases Sec17 from trans-SNARE complexes, inhibiting membrane fusion.

Sec18 ATP 水解选择性地从反式 SNARE 复合物中释放 Sec17，从而抑制膜融合

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E24-12-0561
Lopes Karina, Orr Amy, Wickner William
信号转导
发表日期：2025
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Hexamer structure of Pseudomonas aeruginosa deoxynucleotide triphosphate triphosphohydrolase and its involvement in catalysis and DNA binding

铜绿假单胞菌脱氧核苷三磷酸三磷酸水解酶的六聚体结构及其在催化和DNA结合中的作用

期刊:
影响因子:
doi:10.1101/2025.10.21.683730
Orr, Amy; Lopes, Karina; O'Dwyer, Jerry; Wickner, William; Byeol Oh, Han; Yoon, Sung-il
发表日期：2025
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After their membrane assembly, Sec18 (NSF) and Sec17 (SNAP) promote membrane fusion.

Sec18 (NSF) 和 Sec17 (SNAP) 在膜组装完成后促进膜融合

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E24-10-0439
Song Hongki, Lopes Karina, Orr Amy, Wickner William
NSF
发表日期：2024
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Membrane fusion reactions limited by defective SNARE zippering or stiff lipid fatty acyl composition have distinct requirements for Sec17, Sec18, and adenine nucleotide.

受 SNARE 拉链缺陷或脂质脂肪酰组成僵硬限制的膜融合反应对 Sec17、Sec18 和腺嘌呤核苷酸有不同的要求

期刊:
影响因子:
doi:10.1101/2024.11.15.623832
Lopes Karina, Orr Amy, Wickner William
发表日期：2024
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Phosphatidylinositol and phosphatidylinositol-3-phosphate activate HOPS to catalyze SNARE assembly, allowing small headgroup lipids to support the terminal steps of membrane fusion.

磷脂酰肌醇和磷脂酰肌醇-3-磷酸激活 HOPS 以催化 SNARE 组装，使小头基脂质能够支持膜融合的最后步骤

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E21-07-0373
Torng Thomas, Wickner William
表观遗传
发表日期：2021
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A Rab prenyl membrane-anchor allows effector recognition to be regulated by guanine nucleotide.

Rab蛋白的异戊二烯膜锚定结构允许效应物识别受鸟嘌呤核苷酸调控

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2000923117
Lee Miriam, Wickner William, Song Hongki
免疫/内分泌
发表日期：2020
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Sec17 (α-SNAP) and Sec18 (NSF) restrict membrane fusion to R-SNAREs, Q-SNAREs, and SM proteins from identical compartments.

Sec17 (α-SNAP) 和 Sec18 (NSF) 将膜融合限制在来自相同区室的 R-SNARE、Q-SNARE 和 SM 蛋白

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1913985116
Jun Youngsoo, Wickner William
免疫/内分泌
发表日期：2019
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Tethering guides fusion-competent trans-SNARE assembly.

系链引导具有融合能力的跨 SNARE 组装

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1907640116
Song Hongki, Wickner William
发表日期：2019
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