日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB

放线菌转录因子WhiA和WhiB双重激活细胞分裂的结构基础

Lilic, Mirjana; Holmes, Neil A; Bush, Matthew J; Marti, Alexandra K; Widdick, David A; Findlay, Kim C; Choi, Young Joo; Froom, Ruby; Koh, Steven; Buttner, Mark J; Campbell, Elizabeth A

In Situ Activation and Heterologous Production of a Cryptic Lantibiotic from an African Plant Ant-Derived Saccharopolyspora Species

非洲植物蚁源糖多孢菌属隐性兰替生素的原位激活和异源生产

Vikeli, Eleni; Widdick, David A; Batey, Sibyl F D; Heine, Daniel; Holmes, Neil A; Bibb, Mervyn J; Martins, Dino J; Pierce, Naomi E; Hutchings, Matthew I; Wilkinson, Barrie

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design

DPAGT1 的结构解释糖基化疾病机制并促进结核病抗生素设计

Yin Yao Dong, Hua Wang, Ashley C W Pike, Stephen A Cochrane, Sadra Hamedzadeh, Filip J Wyszyński, Simon R Bushell, Sylvain F Royer, David A Widdick, Andaleeb Sajid, Helena I Boshoff, Yumi Park, Ricardo Lucas, Wei-Min Liu, Seung Seo Lee, Takuya Machida, Leanne Minall, Shahid Mehmood, Katsiaryna Belay

Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity

对链霉菌衣霉素生物合成基因簇的分析揭示了衣霉素生产和免疫的新见解

David Widdick, Sylvain F Royer, Hua Wang, Natalia M Vior, Juan Pablo Gomez-Escribano, Benjamin G Davis, Mervyn J Bibb

A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646

一种新的免疫机制控制着肉桂链霉菌DSM 40646中肉桂霉素生物合成的启动

O'Rourke, Sean; Widdick, David; Bibb, Mervyn

Cosmid based mutagenesis causes genetic instability in Streptomyces coelicolor, as shown by targeting of the lipoprotein signal peptidase gene

基于粘粒的诱变会导致链霉菌(Streptomyces coelicolor)的遗传不稳定,这已通过靶向脂蛋白信号肽酶基因得到证实。

Munnoch, John T; Widdick, David A; Chandra, Govind; Sutcliffe, Iain C; Palmer, Tracy; Hutchings, Matthew I

Formation of functional Tat translocases from heterologous components

由异源成分形成功能性Tat转位酶

Hicks, Matthew G; Guymer, David; Buchanan, Grant; Widdick, David A; Caldelari, Isabelle; Berks, Ben C; Palmer, Tracy

Prediction of twin-arginine signal peptides

双精氨酸信号肽的预测

Bendtsen, Jannick Dyrløv; Nielsen, Henrik; Widdick, David; Palmer, Tracy; Brunak, Søren

Specificity determinants of proteolytic processing of Aspergillus PacC transcription factor are remote from the processing site, and processing occurs in yeast if pH signalling is bypassed

曲霉PacC转录因子蛋白水解加工的特异性决定因素远离加工位点,如果绕过pH信号传导,酵母中也会发生加工。

Mingot, J M; Tilburn, J; Diez, E; Bignell, E; Orejas, M; Widdick, D A; Sarkar, S; Brown, C V; Caddick, M X; Espeso, E A; Arst, H N Jr; Peñalva, M A

The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH

曲霉PacC锌指转录因子通过环境pH值调控酸性和碱性表达基因。

Tilburn, J; Sarkar, S; Widdick, D A; Espeso, E A; Orejas, M; Mungroo, J; Peñalva, M A; Arst, H N Jr