日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PanERBB CAR T-cells: Shifting gears toward a cure for fanconi anemia head/neck cancers

PanERBB CAR T细胞:为治愈范可尼贫血症和头颈癌带来新的希望

Wiek, Constanze; Hüsken, Saskia; Scheckenbach, Kathrin; Eikelberg, Ivana; Niktoreh, Naghmeh; Hanenberg, Helmut

Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.

对猿类和人类的 CYP4B1 酶进行功能分析,揭示了催化功能适应的进化热点

Hüsken Saskia, Röder Annika, Ptok Johannes, Meyer Anne E, Georg Mats, Schwarz Yannick, Roos Christian, Mätz-Rensing Kerstin, Hutter Michael C, Floss Doreen M, Rettie Allan E, Girhard Marco, Hanenberg Helmut, Wiek Constanze

Spotlight on CYP4B1

聚焦CYP4B1

Röder, Annika; Hüsken, Saskia; Hutter, Michael C; Rettie, Allan E; Hanenberg, Helmut; Wiek, Constanze; Girhard, Marco

Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury

来自永生化间充质干细胞的细胞外囊泡可保护新生儿免受缺氧缺血性脑损伤

Labusek, Nicole; Mouloud, Yanis; Köster, Christian; Diesterbeck, Eva; Tertel, Tobias; Wiek, Constanze; Hanenberg, Helmut; Horn, Peter A; Felderhoff-Müser, Ursula; Bendix, Ivo; Giebel, Bernd; Herz, Josephine

Genetic Engineering and Enrichment of Human NK Cells for CAR-Enhanced Immunotherapy of Hematological Malignancies

利用基因工程和富集技术改造人类NK细胞,用于CAR增强型血液恶性肿瘤免疫治疗

Soldierer, Maren; Bister, Arthur; Haist, Corinna; Thivakaran, Aniththa; Cengiz, Sevgi Can; Sendker, Stephanie; Bartels, Nina; Thomitzek, Antonia; Smorra, Denise; Hejazi, Maryam; Uhrberg, Markus; Scheckenbach, Kathrin; Monzel, Cornelia; Wiek, Constanze; Reinhardt, Dirk; Niktoreh, Naghmeh; Hanenberg, Helmut

Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells

利用地西他滨对膀胱癌细胞进行表观遗传学预处理可增强人 EGFR 和 CD44v6 CAR 工程化 T 细胞的细胞毒性

Grunewald, Camilla M; Haist, Corinna; König, Carolin; Petzsch, Patrick; Bister, Arthur; Nößner, Elfriede; Wiek, Constanze; Scheckenbach, Kathrin; Köhrer, Karl; Niegisch, Günter; Hanenberg, Helmut; Hoffmann, Michèle J

The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas

头颈部鳞状细胞癌中CD28、CD80、CD86、CTLA4和ICOS DNA甲基化图谱

de Vos, Luka; Grünwald, Ingela; Bawden, Emma Grace; Dietrich, Jörn; Scheckenbach, Kathrin; Wiek, Constanze; Zarbl, Romina; Bootz, Friedrich; Landsberg, Jennifer; Dietrich, Dimo

The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling

具有CARD结构域的凋亡抑制因子(ARC)在肾细胞癌(RCC)治疗耐药中的作用:ARC在抑制外源性和内源性凋亡信号传导中的关键作用

Toth, Csaba; Funke, Sarah; Nitsche, Vanessa; Liverts, Anna; Zlachevska, Viktoriya; Gasis, Marcia; Wiek, Constanze; Hanenberg, Helmut; Mahotka, Csaba; Schirmacher, Peter; Heikaus, Sebastian

Complementation of hypersensitivity to DNA interstrand crosslinking agents demonstrates that XRCC2 is a Fanconi anaemia gene

对DNA链间交联剂超敏反应的互补性表明,XRCC2是范可尼贫血基因。

Park, Jung-Young; Virts, Elizabeth L; Jankowska, Anna; Wiek, Constanze; Othman, Mohamed; Chakraborty, Sujata C; Vance, Gail H; Alkuraya, Fowzan S; Hanenberg, Helmut; Andreassen, Paul R

Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicity

姜黄素衍生的芳基庚烷类化合物的设计、合成及对胶质母细胞瘤和神经母细胞瘤细胞毒性的评价

Campos, Catherine A; Gianino, Joseph B; Bailey, Barbara J; Baluyut, Mary E; Wiek, Constanze; Hanenberg, Helmut; Shannon, Harlan E; Pollok, Karen E; Ashfeld, Brandon L