The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins
ALS 关联的 Sigma 受体 1 中的 E102Q 突变导致 ER 应激介导的蛋白质稳态缺陷和 RNA 结合蛋白失调
期刊:Cell Death and Differentiation
影响因子:13.7
doi:10.1038/cdd.2017.88
Alice Dreser, Jan Tilmann Vollrath, Antonio Sechi, Sonja Johann, Andreas Roos, Alfred Yamoah, Istvan Katona, Saeed Bohlega, Dominik Wiemuth, Yuemin Tian, Axel Schmidt, Jörg Vervoorts, Marc Dohmen, Cordian Beyer, Jasper Anink, Eleonora Aronica, Dirk Troost, Joachim Weis, Anand Goswami
