日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An evaluation of a supratherapeutic dose of inclisiran on cardiac repolarization in healthy volunteers: A phase I, randomized study.

评估超治疗剂量的inclisiran对健康志愿者心脏复极化的影响:一项 I 期随机研究

Kallend David, Mason Jay, Smith Patrick F, Koren Michael J, Stoekenbroek Robert, He YanLing, Wijngaard Peter

Effect of 1 or 2 Doses of Inclisiran on Low-Density Lipoprotein Cholesterol Levels: One-Year Follow-up of the ORION-1 Randomized Clinical Trial

剂或 2 剂 Inclisiran 对低密度脂蛋白胆固醇水平的影响:ORION-1 随机临床试验的一年随访

Ray, Kausik K; Stoekenbroek, Robert M; Kallend, David; Nishikido, Toshiyuki; Leiter, Lawrence A; Landmesser, Ulf; Wright, R Scott; Wijngaard, Peter L J; Kastelein, John J P

Effect of Infusion of High-Density Lipoprotein Mimetic Containing Recombinant Apolipoprotein A-I Milano on Coronary Disease in Patients With an Acute Coronary Syndrome in the MILANO-PILOT Trial: A Randomized Clinical Trial

在 MILANO-PILOT 试验中,输注含重组载脂蛋白 AI Milano 的高密度脂蛋白模拟物对急性冠脉综合征患者冠状动脉疾病的影响:一项随机临床试验

Nicholls, Stephen J; Puri, Rishi; Ballantyne, Christie M; Jukema, J Wouter; Kastelein, John J P; Koenig, Wolfgang; Wright, R Scott; Kallend, David; Wijngaard, Peter; Borgman, Marilyn; Wolski, Kathy; Nissen, Steven E

A Highly Durable RNAi Therapeutic Inhibitor of PCSK9

一种高度持久的PCSK9 RNAi治疗抑制剂

Fitzgerald, Kevin; White, Suellen; Borodovsky, Anna; Bettencourt, Brian R; Strahs, Andrew; Clausen, Valerie; Wijngaard, Peter; Horton, Jay D; Taubel, Jorg; Brooks, Ashley; Fernando, Chamikara; Kauffman, Robert S; Kallend, David; Vaishnaw, Akshay; Simon, Amy

Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size

将 MDCO-216 (ApoA-IMilano/POPC) 与人血清孵育可增强 ABCA1 介导的胆固醇外流能力,生成新的前β-1 HDL,并导致 HDL 颗粒增大。

Kempen, Herman J; Schranz, Dorota B; Asztalos, Bela F; Otvos, James; Jeyarajah, Elias; Drazul-Schrader, Denise; Collins, Heidi L; Adelman, Steven J; Wijngaard, Peter L J

Effect of repeated apoA-IMilano/POPC infusion on lipids, (apo)lipoproteins, and serum cholesterol efflux capacity in cynomolgus monkeys

重复输注apoA-IMilano/POPC对食蟹猴脂质、(载脂)脂蛋白和血清胆固醇外流能力的影响

Kempen, Herman J; Gomaraschi, Monica; Bellibas, S Eralp; Plassmann, Stephanie; Zerler, Brad; Collins, Heidi L; Adelman, Steven J; Calabresi, Laura; Wijngaard, Peter L J