日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn's disease

结肠活检相关的微生物特征可预测克罗恩病患者对TNFα抑制剂生物疗法的反应

Zafeiropoulou, Konstantina; Hageman, Ishtu L; Mu, Tianqi; Davids, Mark; Li Yim, Andrew Y F; Joustra, Vincent W; Hakvoort, Theodorus B M; Satsangi, Jack; Chronas, Konstantinos; Koelink, Pim J; Wildenberg, Manon E; van den Wijngaard, Rene M; D'Haens, Geert R; de Jonge, Wouter J

Mucosal B Cell Expansion and Maturation Contribute to Colitis Pathogenesis.

黏膜B细胞的扩增和成熟是结肠炎发病机制的促成因素。

Fung Ivan C N, Koelink Pim J, Mulders Lieven G M, Admiraal Iris, Verseijden Caroline, Verhoeff Jan, Wildenberg Manon E, Luo Yi, D'Haens Geert R, Li Yim Andrew Y F, de Jonge Wouter J

Effects of specialized proresolving mediators on gut epithelial barrier in early life

早期生活中特化的促消退介质对肠道上皮屏障的影响

Chen, Jing; Ouahoud, Sarah; Schreurs, Renee R C E; Meisner, Sander; Vermeulen, Jacqueline L M; Wildenberg, Manon E; de Jonge, Wouter J; van Goudoever, Johannes B; de Meij, Tim G J; Muncan, Vanesa; van den Akker, Chris H P

Clinical relevance of calprotectin in patients with perianal fistulas in Crohn's disease and cryptoglandular fistulas

钙卫蛋白在克罗恩病和隐窝腺瘘患者肛周瘘中的临床意义

Becker, Marte A J; Stevens, Toer W; de Voogd, Floris A E; Wildenberg, Manon E; D'Haens, Geert R A M; Gecse, Krisztina B; Buskens, Christianne J

An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn's disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes

对接受维多珠单抗治疗的克罗恩病患者外周血单核细胞进行探索性单细胞分析,发现浆细胞样树突状细胞和经典单核细胞之间存在与治疗反应相关的差异。

Li Yim, Andrew Yung Fong; Hageman, Ishtu; Joustra, Vincent W; Elfiky, Ahmed M I M; Ghiboub, Mohammed; Levin, Evgeni; Verhoeff, Jan; Verseijden, Caroline; Admiraal, Iris; de Krijger, Manon; Wildenberg, Manon E; Mannens, Marcel; Jakobs, Marja E; Kenter, Susan B; Adams, Alex T; Satsangi, Jack; D'Haens, Geert R; de Jonge, Wouter J; Henneman, Peter

Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection

增强自噬的策略可促进肠道对SARS-CoV-2感染的病毒抵抗力和黏膜屏障功能

Rader, Anusca G; Cloherty, Alexandra P M; Patel, Kharishma S; Almandawi, Dima D A; Perez-Vargas, Jimena; Wildenberg, Manon E; Muncan, Vanesa; Schreurs, Renée R C E; Jean, François; Ribeiro, Carla M S

T-cell responses in colorectal peritoneal metastases are recapitulated in a humanized immune system mouse model

在人源化免疫系统小鼠模型中,结直肠癌腹膜转移灶中的T细胞反应得以重现。

Saris, Job; Bootsma, Sanne; Verhoeff, Jan; Tuynman, Jurriaan B; Wildenberg, Manon E; Rijnstra, Esther Siteur-van; Lenos, Kristiaan J; Garcia Vallejo, Juan J; Vermeulen, Louis; Grootjans, Joep

Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease

羧酸酯酶-1辅助HDAC抑制剂靶向炎症性肠病中的单核髓系细胞

Elfiky, Ahmed M I; Ghiboub, Mohammed; Li Yim, Andrew Y F; Hageman, Ishtu L; Verhoeff, Jan; de Krijger, Manon; van Hamersveld, Patricia H P; Welting, Olaf; Admiraal, Iris; Rahman, Shafaque; Garcia-Vallejo, Juan J; Wildenberg, Manon E; Tomlinson, Laura; Gregory, Richard; Rioja, Inmaculada; Prinjha, Rab K; Furze, Rebecca C; Lewis, Huw D; Mander, Palwinder K; Heinsbroek, Sigrid E M; Bell, Matthew J; de Jonge, Wouter J

A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn's Disease

一种靶向单核髓系细胞的BET蛋白抑制剂可影响克罗恩病中的特定炎症介质和通路

Elfiky, Ahmed M I; Hageman, Ishtu L; Becker, Marte A J; Verhoeff, Jan; Li Yim, Andrew Y F; Joustra, Vincent W; Mulders, Lieven; Fung, Ivan; Rioja, Inmaculada; Prinjha, Rab K; Smithers, Nicholas N; Furze, Rebecca C; Mander, Palwinder K; Bell, Matthew J; Buskens, Christianne J; D'Haens, Geert R; Wildenberg, Manon E; de Jonge, Wouter J

Role of the Mesentery in Crohn's Terminal Ileitis

肠系膜在克罗恩病末端回肠炎中的作用

Becker, Marte A J; Does de Willebois, Eline M L van der; Bemelman, Willem A; Wildenberg, Manon E; Buskens, Christianne J