日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors

N-甲基-D-天冬氨酸受体亚基选择性正向变构调节的GluN1和GluN2结构决定因素

Strong, Katie L; Epplin, Matthew P; Ogden, Kevin K; Burger, Pieter B; Kaiser, Thomas M; Wilding, Timothy J; Kusumoto, Hiro; Camp, Chad R; Shaulsky, Gil; Bhattacharya, Subhrajit; Perszyk, Riley E; Menaldino, David S; McDaniel, Miranda J; Zhang, Jing; Le, Phuong; Banke, Tue G; Hansen, Kasper B; Huettner, James E; Liotta, Dennis C; Traynelis, Stephen F

Cadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions

镉通过M3螺旋半胱氨酸取代激活AMPA和NMDA受体

Wilding, Timothy J; Huettner, James E

Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

可视化孕烯醇酮硫酸酯样NMDA受体功能调节剂揭示了其细胞内和质膜定位

Chisari, Mariangela; Wilding, Timothy J; Brunwasser, Samuel; Krishnan, Kathiresan; Qian, Mingxing; Benz, Ann; Huettner, James E; Zorumski, Charles F; Covey, Douglas F; Mennerick, Steven

Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing

镉通过M3螺旋束交叉处的半胱氨酸取代打开GluK2红藻氨酸受体

Wilding, Timothy J; Huettner, James E

Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains.

嵌合谷氨酸受体亚基揭示跨膜结构域足以决定 NMDA 受体孔的特性,但一些正向变构调节剂需要额外的结构域

Wilding Timothy J, Lopez Melany N, Huettner James E

Radial symmetry in a chimeric glutamate receptor pore.

嵌合谷氨酸受体孔的放射状对称性

Wilding Timothy J, Lopez Melany N, Huettner James E

Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis

通过扫描诱变分析脂肪酸调节和多胺阻断GluK2红藻氨酸受体

Wilding, Timothy J; Chen, Kevin; Huettner, James E

The BTB/kelch protein, KRIP6, modulates the interaction of PICK1 with GluR6 kainate receptors

BTB/kelch蛋白KRIP6调节PICK1与GluR6红藻氨酸受体的相互作用

Laezza, Fernanda; Wilding, Timothy J; Sequeira, Sunitha; Craig, Ann Marie; Huettner, James E

Amino acid substitutions in the pore helix of GluR6 control inhibition by membrane fatty acids.

GluR6 孔道螺旋中的氨基酸取代控制膜脂肪酸的抑制作用

Wilding Timothy J, Fulling Elisabeth, Zhou Yun, Huettner James E

KRIP6: a novel BTB/kelch protein regulating function of kainate receptors

KRIP6:一种新型的BTB/kelch蛋白,可调节红藻氨酸受体的功能

Laezza, Fernanda; Wilding, Timothy J; Sequeira, Sunitha; Coussen, Françoise; Zhang, Xue Zhao; Hill-Robinson, Rona; Mulle, Christophe; Huettner, James E; Craig, Ann Marie