日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduced Gene Dosage of the Psychiatric Risk Gene Cacna1c Is Associated with Impairments in Hypothalamic-Pituitary-Adrenal Axis Activity in Rats.

精神疾病风险基因 Cacna1c 的基因剂量降低与大鼠下丘脑-垂体-肾上腺轴活动受损有关

Moon Anna L, Mawson Eleanor R, Gasalla Patricia, Wilkinson Lawrence S, Dwyer Dominic M, Hall Jeremy, Thomas Kerrie L

Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility

将自闭症和精神分裂症相关基因 Cyfip1 的单倍体不足与纹状体-边缘-皮质网络功能障碍和认知僵化联系起来

Haddon, Josephine E; Titherage, Daniel; Heckenast, Julia R; Carter, Jennifer; Owen, Michael J; Hall, Jeremy; Wilkinson, Lawrence S; Jones, Matthew W

Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour

Setd1a单倍体不足对发育和成年行为的性别依赖性影响

Bosworth, Matthew L; Isles, Anthony R; Wilkinson, Lawrence S; Humby, Trevor

A mild impairment in reversal learning in a bowl-digging substrate deterministic task but not other cognitive tests in the Dlg2+/- rat model of genetic risk for psychiatric disorder

在Dlg2+/-大鼠模型(该模型具有精神疾病遗传风险)中,在碗状挖掘基质确定性任务中表现出轻微的逆转学习障碍,但在其他认知测试中未见此现象。

Griesius, Simonas; Waldron, Sophie; Kamenish, Katie A; Cherbanich, Nick; Wilkinson, Lawrence S; Thomas, Kerrie L; Hall, Jeremy; Mellor, Jack R; Dwyer, Dominic M; Robinson, Emma S J

Analysis of Diffusion Tensor Imaging Data From the UK Biobank Confirms Dosage Effect of 15q11.2 Copy Number Variation on White Matter and Shows Association With Cognition

对英国生物银行扩散张量成像数据的分析证实了15q11.2拷贝数变异对白质的剂量效应,并显示其与认知功能相关。

Silva, Ana I; Kirov, George; Kendall, Kimberley M; Bracher-Smith, Mathew; Wilkinson, Lawrence S; Hall, Jeremy; Ulfarsson, Magnus O; Walters, G Bragi; Stefansson, Hreinn; Stefansson, Kari; Linden, David E J; Caseras, Xavier

Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

精神分裂症和自闭症风险基因Cyfip1的单倍体不足会导致出生后海马神经发生异常,其机制涉及小胶质细胞和Arp2/3介导的肌动蛋白依赖性机制。

Haan, Niels; Westacott, Laura J; Carter, Jenny; Owen, Michael J; Gray, William P; Hall, Jeremy; Wilkinson, Lawrence S

Cacna1c Hemizygosity Results in Aberrant Fear Conditioning to Neutral Stimuli

Cacna1c半合子状态导致对中性刺激的异常恐惧条件反射

Moon, Anna L; Brydges, Nichola M; Wilkinson, Lawrence S; Hall, Jeremy; Thomas, Kerrie L

Effects of 5-HT(2C), 5-HT(1A) receptor challenges and modafinil on the initiation and persistence of gambling behaviours

5-HT(2C)、5-HT(1A)受体刺激和莫达非尼对赌博行为的发生和持续的影响

Humby, Trevor; Smith, Georgia E; Small, Rebecca; Davies, William; Carter, Jenny; Bentley, Chloe A; Winstanley, Catharine A; Rogers, Robert D; Wilkinson, Lawrence S

FMRP and CYFIP1 at the Synapse and Their Role in Psychiatric Vulnerability

突触处的FMRP和CYFIP1及其在精神疾病易感性中的作用

Clifton, Nicholas E; Thomas, Kerrie L; Wilkinson, Lawrence S; Hall, Jeremy; Trent, Simon

Reciprocal White Matter Changes Associated With Copy Number Variation at 15q11.2 BP1-BP2: A Diffusion Tensor Imaging Study

15q11.2 BP1-BP2 拷贝数变异相关的白质互惠性改变:一项弥散张量成像研究

Silva, Ana I; Ulfarsson, Magnus O; Stefansson, Hreinn; Gustafsson, Omar; Walters, G Bragi; Linden, David E J; Wilkinson, Lawrence S; Drakesmith, Mark; Owen, Michael J; Hall, Jeremy; Stefansson, Kari