日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of antiphage defence by an ATPase-associated reverse transcriptase

ATPase相关逆转录酶介导的抗噬菌体防御的结构基础

George, Jerrin Thomas; Burman, Nathaniel; Wilkinson, Royce A; de Silva, Senuri; McKelvey-Pham, Quynh; Buyukyoruk, Murat; Dale, Adelaide; Landman, Hannah; Graham, Ava B; DeLuca, Steven Z; Wiedenheft, Blake

Protein-primed DNA homopolymer synthesis by an antiviral reverse transcriptase.

抗病毒逆转录酶引发的蛋白质引物DNA同聚物合成

Tang Stephen, Žedaveinytė Rimantė, Burman Nathaniel, Pandey Shishir, Ramirez Josephine L, Kulber Louie M, Wiegand Tanner, Wilkinson Royce A, Ma Yanzhe, Zhang Dennis J, Lampe George D, Berisa Mirela, Jovanovic Marko, Wiedenheft Blake, Sternberg Samuel H

Structural basis of antiphage defense by an ATPase-associated reverse transcriptase.

ATPase相关逆转录酶的抗噬菌体防御的结构基础

George Jerrin Thomas, Burman Nathaniel, Wilkinson Royce A, de Silva Senuri, McKelvey-Pham Quynh, Buyukyoruk Murat, Dale Adelaide, Landman Hannah, Graham Ava, DeLuca Steven Z, Wiedenheft Blake

Author Correction: A virally encoded tRNA neutralizes the PARIS antiviral defence system

作者更正:病毒编码的tRNA能够中和PARIS抗病毒防御系统。

Burman, Nathaniel; Belukhina, Svetlana; Depardieu, Florence; Wilkinson, Royce A; Skutel, Mikhail; Santiago-Frangos, Andrew; Graham, Ava B; Livenskyi, Alexei; Chechenina, Anna; Morozova, Natalia; Zahl, Trevor; Henriques, William S; Buyukyoruk, Murat; Rouillon, Christophe; Saudemont, Baptiste; Shyrokova, Lena; Kurata, Tatsuaki; Hauryliuk, Vasili; Severinov, Konstantin; Groseille, Justine; Thierry, Agnès; Koszul, Romain; Tesson, Florian; Bernheim, Aude; Bikard, David; Wiedenheft, Blake; Isaev, Artem

Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays

结构揭示了基因组折叠对于将外源DNA定点整合到CRISPR阵列中的重要性

Santiago-Frangos, Andrew; Henriques, William S; Wiegand, Tanner; Gauvin, Colin C; Buyukyoruk, Murat; Graham, Ava B; Wilkinson, Royce A; Triem, Lenny; Neselu, Kasahun; Eng, Edward T; Lander, Gabriel C; Wiedenheft, Blake

Anti-CRISPR proteins function through thermodynamic tuning and allosteric regulation of CRISPR RNA-guided surveillance complex

抗CRISPR蛋白通过对CRISPR RNA引导的监视复合物进行热力学调节和变构调控发挥作用。

Patterson, Angela; White, Aidan; Waymire, Elizabeth; Fleck, Sophie; Golden, Sarah; Wilkinson, Royce A; Wiedenheft, Blake; Bothner, Brian

CRISPR-Cas, Argonaute proteins and the emerging landscape of amplification-free diagnostics

CRISPR-Cas、Argonaute蛋白和新兴的无扩增诊断技术

Santiago-Frangos, Andrew; Nemudryi, Artem; Nemudraia, Anna; Wiegand, Tanner; Nichols, Joseph E; Krishna, Pushya; Scherffius, Andrew M; Zahl, Trevor R; Wilkinson, Royce A; Wiedenheft, Blake

CRISPR RNA-guided autonomous delivery of Cas9

CRISPR RNA引导的Cas9自主递送

Wilkinson, Royce A; Martin, Coleman; Nemudryi, Artem A; Wiedenheft, Blake

Improved guanide compounds which bind the CXCR4 co-receptor and inhibit HIV-1 infection

改进的胍类化合物可与CXCR4辅助受体结合并抑制HIV-1感染

Wilkinson, Royce A; Pincus, Seth H; Song, Kejing; Shepard, Joyce B; Weaver, Alan J Jr; Labib, Mohamed E; Teintze, Martin

Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4

含有多个胍基的新型化合物可与 HIV 辅助受体 CXCR4 结合

Wilkinson, Royce A; Pincus, Seth H; Shepard, Joyce B; Walton, Sarah K; Bergin, Edward P; Labib, Mohamed; Teintze, Martin