日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PhuS conformational dynamics are essential for DNA binding and heme-responsive control of the prrF operon in Pseudomonas aeruginosa

PhuS构象动力学对于铜绿假单胞菌中prrF操纵子的DNA结合和血红素响应控制至关重要。

Egoshi, Riki; Huang, Weiliang; Albert, Therese; Kane, Maureen A; Deredge, Daniel; Moënne-Loccoz, Pierre; Wilks, Angela

Quantification of All-Trans Retinoic Acid and Cytokine Levels After Fungal, Viral and Bacterial Infections in the Lung

肺部真菌、病毒和细菌感染后全反式维甲酸和细胞因子水平的定量分析

Krug, Samuel A; Singh, Ravineel; Yu, Jianshi; Witt, William T; Pilli, Nageswara R; Wilks, Angela; Barbier, Mariette; Robinson, Keven M; Kane, Maureen A

Application of preclinical absorption, distribution, metabolism, elimination in vitro techniques for the characterization and compound library optimization of novel antibiotic gallium salophen

应用体外吸收、分布、代谢、消除(ADME)等临床前技术,对新型抗生素镓沙洛芬进行表征和化合物库优化。

Krug, Samuel A; Frank, Aziza; Hwang, Lucia; Worth, Madison; Johnson, Kieran; Rojas, Christine; Muller, Ludovic; Michel, Sarah L J; Wilks, Angela; Xue, Fengtian; Kane, Maureen A

The Pseudomonas aeruginosa PhuS proximal ligand His-209 triggers a conformational switch in function from DNA binding to heme transfer

铜绿假单胞菌 PhuS 近端配体 His-209 可触发构象转变,使其功能从 DNA 结合转变为血红素转移。

Montes, Nicholas; Wilson, Tyree; Krug, Samuel A; Mouriño, Susana; Kane, Maureen A; Deredge, Daniel; Wilks, Angela

GaSal-2: A Water-Soluble Antipseudomonal Agent Targeting the Extracellular Hemophore HasAp

GaSal-2:一种靶向细胞外血红素载体HasAp的水溶性抗假单胞菌药物

Frank, Aziza; Hwang, Lucia; Witt, William T; Centola, Garrick; Johnson, Kieran; Ai, Yong; Sen-Kilic, Emel; Pyles, Gage M; Huckaby, Annalisa B; Blackwood, Catherine B; Miller, Sarah Jo; Hudson, S Matthew; Hom, Kellie; Yu, Wenbo; MacKerell, Alexander D Jr; Barbier, Mariette; Wilks, Angela; Xue, Fengtian

Understanding RNA Binding by the Nonclassical Zinc Finger Protein CPSF30, a Key Factor in Polyadenylation during Pre-mRNA Processing

了解非经典锌指蛋白CPSF30与RNA的结合,CPSF30是前体mRNA加工过程中多聚腺苷酸化的关键因子

Pritts, Jordan D; Oluyadi, Abdulafeez A; Huang, Weiliang; Shimberg, Geoffrey D; Kane, Maureen A; Wilks, Angela; Michel, Sarah L J

Extracellular haem utilization by the opportunistic pathogen Pseudomonas aeruginosa and its role in virulence and pathogenesis

机会性致病菌铜绿假单胞菌对胞外血红素的利用及其在毒力和致病性中的作用

Mouriño, Susana; Wilks, Angela

Metallotherapeutics development in the age of iron-clad bacteria

铁甲细菌时代的金属疗法发展

Centola, Garrick; Xue, Fengtian; Wilks, Angela

Post-transcriptional regulation of the Pseudomonas aeruginosa heme assimilation system (Has) fine-tunes extracellular heme sensing

铜绿假单胞菌血红素同化系统 (Has) 的转录后调控精细调节胞外血红素感知

Dent, Alecia T; Mouriño, Susana; Huang, Weiliang; Wilks, Angela

Proteomic Analysis of the Pseudomonas aeruginosa Iron Starvation Response Reveals PrrF Small Regulatory RNA-Dependent Iron Regulation of Twitching Motility, Amino Acid Metabolism, and Zinc Homeostasis Proteins

铜绿假单胞菌铁饥饿反应的蛋白质组学分析揭示了 PrrF 小调控 RNA 依赖的铁调控作用,该作用涉及颤搐运动、氨基酸代谢和锌稳态蛋白。

Nelson, Cassandra E; Huang, Weiliang; Brewer, Luke K; Nguyen, Angela T; Kane, Maureen A; Wilks, Angela; Oglesby-Sherrouse, Amanda G