日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking.

利用酵母展示技术筛选大环肽库可以控制选择过程和亲和力排序

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60907-x
Linciano Sara, Mazzocato Ylenia, Romanyuk Zhanna, Vascon Filippo, Farrera-Soler Lluc, Will Edward, Xing Yuyu, Chen Shiyu, Kumada Yoichi, Simeoni Marta, Scarso Alessandro, Cendron Laura, Heinis Christian, Angelini Alessandro
其它
Yeast
发表日期：2025
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Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11

组蛋白去乙酰化酶11的从头大环抑制剂的发现

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.4c01148
Danková, Daniela; Nielsen, Alexander L; Zarda, Anne; Hansen, Tobias N; Hesse, Marie; Benová, Michaela; Tsiris, Athanasios; Bartling, Christian R O; Will, Edward J; Strømgaard, Kristian; Moreno-Yruela, Carlos; Heinis, Christian; Olsen, Christian A
乙酰化
表观遗传
发表日期：2025
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2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A(1) Adenosine Receptor Positive Allosteric Modulators

2-氨基-5-芳基乙炔基-噻吩-3-基-(苯基)甲酮作为A(1)腺苷受体正向变构调节剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00315
Oliva, Paola; Suresh, R Rama; Pasquini, Silvia; Salmaso, Veronica; Will, Edward J; Tosh, Dilip K; Gao, Zhan-Guo; Liu, Naili; Gavrilova, Oksana; Vincenzi, Fabrizio; Varani, Katia; Jacobson, Kenneth A
信号转导
发表日期：2023
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Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity

发现一种高效且选择性的共价抑制剂和活性探针，用于靶向去泛素化酶UCHL1，具有抗纤维化活性

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.0c04527
Panyain, Nattawadee; Godinat, Aurélien; Lanyon-Hogg, Thomas; Lachiondo-Ortega, Sofía; Will, Edward J; Soudy, Christelle; Mondal, Milon; Mason, Katie; Elkhalifa, Sarah; Smith, Lisa M; Harrigan, Jeanine A; Tate, Edward W
表观遗传
UCHL1
泛素化
发表日期：2020
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Correction to "Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity"

对“发现一种高效选择性共价抑制剂和去泛素化酶UCHL1活性探针，具有抗纤维化活性”一文的更正

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.0c08385
Panyain, Nattawadee; Godinat, Aurélien; Lanyon-Hogg, Thomas; Lachiondo-Ortega, Sofía; Will, Edward J; Soudy, Christelle; Mondal, Milon; Mason, Katie; Elkhalifa, Sarah; Smith, Lisa M; Harrigan, Jeanine A; Tate, Edward W
UCHL1
泛素化
表观遗传
发表日期：2020
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