日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A candidate antibody drug for prevention of malaria

一种用于预防疟疾的候选抗体药物

Katherine L Williams ,Steve Guerrero ,Yevel Flores-Garcia ,Dongkyoon Kim ,Kevin S Williamson ,Christine Siska ,Pauline Smidt ,Sofia Z Jepson ,Kan Li ,S Moses Dennison ,Shamika Mathis-Torres ,Xiaomu Chen ,Ulrike Wille-Reece ,Randall S MacGill ,Michael Walker ,Erik Jongert ,C Richter King ,Christian Ockenhouse ,Jacob Glanville ,James E Moon ,Jason A Regules ,Yann Chong Tan ,Guy Cavet ,Shaun M Lippow ,William H Robinson ,Sheetij Dutta ,Georgia D Tomaras ,Fidel Zavala ,Randal R Ketchem ,Daniel E Emerling

Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection

鉴定RTS,S/AS01疫苗诱导的体液生物标志物,以预测对受控人类疟疾感染的保护作用

Spreng, Rachel L; Seaton, Kelly E; Lin, Lin; Hilliard, Sir'Tauria; Horn, Gillian Q; Abraha, Milite; Deal, Aaron W; Li, Kan; Carnacchi, Alexander J; Feeney, Elizabeth; Shabbir, Siam; Zhang, Lu; Bekker, Valerie; Mudrak, Sarah V; Dutta, Sheetij; Mercer, Laina D; Gregory, Scott; King, C Richter; Wille-Reece, Ulrike; Jongert, Erik; Kisalu, Neville K; Tomaras, Georgia D; Dennison, S Moses

A tool for evaluating heterogeneity in avidity of polyclonal antibodies

评估多克隆抗体亲和力异质性的工具

Kan Li, Michael Dodds, Rachel L Spreng, Milite Abraha, Richard H C Huntwork, Lindsay C Dahora, Tinashe Nyanhete, Sheetij Dutta, Ulrike Wille-Reece, Erik Jongert, Katie J Ewer, Adrian V S Hill, Celina Jin, Jennifer Hill, Andrew J Pollard, S Munir Alam, Georgia D Tomaras, S Moses Dennison

Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies

RTS,S/AS01 延迟分次给药可通过平衡多功能 NANP6 和 Pf16 特异性抗体来改善对疟疾的体液免疫

Jishnu Das, Jonathan K Fallon, Timothy C Yu, Ashlin Michell, Todd J Suscovich, Caitlyn Linde, Harini Natarajan, Joshua Weiner, Margherita Coccia, Scott Gregory, Margaret E Ackerman, Elke Bergmann-Leitner, Laura Fontana, Sheetij Dutta, Douglas A Lauffenburger, Erik Jongert, Ulrike Wille-Reece, Galit

Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection

环子孢子蛋白特异性抗体的亚类和亲和力与疟疾感染的保护状态相关

Kelly E Seaton #, Rachel L Spreng #, Milite Abraha, Matthew Reichartz, Michelle Rojas, Frederick Feely 2nd, Richard H C Huntwork, Sheetij Dutta, Sarah V Mudrak, S Munir Alam, Scott Gregory, Erik Jongert, Margherita Coccia, Fernando Ulloa-Montoya, Ulrike Wille-Reece, Georgia D Tomaras #, S Moses Denn

Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Trials

综合数据整合方法评估受控人类疟疾感染试验中的免疫反应和 RTS、S/AS01 介导的疟疾感染保护相关性

William Chad Young, Lindsay N Carpp, Sidhartha Chaudhury, Jason A Regules, Elke S Bergmann-Leitner, Christian Ockenhouse, Ulrike Wille-Reece, Allan C deCamp, Ellis Hughes, Celia Mahoney, Suresh Pallikkuth, Savita Pahwa, S Moses Dennison, Sarah V Mudrak, S Munir Alam, Kelly E Seaton, Rachel L Spreng,

A delayed fractionated dose RTS,S AS01 vaccine regimen mediates protection via improved T follicular helper and B cell responses

延迟分次给药的RTS,S AS01疫苗方案通过增强T滤泡辅助细胞和B细胞反应发挥保护作用。

Suresh Pallikkuth ,Sidhartha Chaudhury ,Pinyi Lu ,Li Pan ,Erik Jongert ,Ulrike Wille-Reece ,Savita Pahwa

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

单独使用RTS,S/AS01B或与表达ME-TRAP的ChAd63-MVA载体疫苗联合使用,评估新型疟疾疫苗方案的安全性和有效性

Rampling, Tommy; Ewer, Katie J; Bowyer, Georgina; Edwards, Nick J; Wright, Danny; Sridhar, Saranya; Payne, Ruth; Powlson, Jonathan; Bliss, Carly; Venkatraman, Navin; Poulton, Ian D; de Graaf, Hans; Gbesemete, Diane; Grobbelaar, Amy; Davies, Huw; Roberts, Rachel; Angus, Brian; Ivinson, Karen; Weltzin, Rich; Rajkumar, Bebi-Yassin; Wille-Reece, Ulrike; Lee, Cynthia; Ockenhouse, Chris; Sinden, Robert E; Gerry, Stephen C; Lawrie, Alison M; Vekemans, Johan; Morelle, Danielle; Lievens, Marc; Ballou, Ripley W; Lewis, David J M; Cooke, Graham S; Faust, Saul N; Gilbert, Sarah; Hill, Adrian V S

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25

TLR 佐剂纳米颗粒疫苗对疟疾抗原 Pfs25 反应的质量和持续时间有不同的影响

Elizabeth A Thompson, Sebastian Ols, Kazutoyo Miura, Kelly Rausch, David L Narum, Mats Spångberg, Michal Juraska, Ulrike Wille-Reece, Amy Weiner, Randall F Howard, Carole A Long, Patrick E Duffy, Lloyd Johnston, Conlin P O'Neil, Karin Loré

Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens

合格的生物层干涉亲和力测量可区分抗体与恶性疟原虫环子孢子蛋白抗原相互作用的异质性

S Moses Dennison, Matthew Reichartz, Kelly E Seaton, Sheetij Dutta, Ulrike Wille-Reece, Adrian V S Hill, Katie J Ewer, Wes Rountree, Marcella Sarzotti-Kelsoe, Daniel A Ozaki, S Munir Alam, Georgia D Tomaras