日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dietary fructo-oligosaccharides dose-dependently modulate the microbiome and suppress type 2 lung inflammation in a murine model of house dust mite-induced allergic asthma

膳食低聚果糖以剂量依赖的方式调节肠道菌群，并抑制屋尘螨诱发的过敏性哮喘小鼠模型中的2型肺部炎症。

期刊:Frontiers in Nutrition
影响因子:5.1
doi:10.3389/fnut.2026.1705988
Verstegen, Roos E M; de Bruijn, Marjolein J W; Garssen, Johan; Folkerts, Gert; Kostadinova, Atanaska I; Hendriks, Rudi W; Willemsen, Linette E M
肺炎
哮喘
炎症
炎症/感染
微生物学
肠道菌群
发表日期：2026
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Ex vivo allergen specific type 2 immune responses in house dust mite-driven acute airway inflammation in mice depend on allergen extract characteristics

小鼠体内由屋尘螨引起的急性气道炎症中，体外过敏原特异性2型免疫反应取决于过敏原提取物的特性。

期刊:Respiratory Research
影响因子:5
doi:10.1186/s12931-026-03563-z
Verstegen, Roos E M; Thijssen, Suzan; Kostadinova, Atanaska I; Garssen, Johan; Folkerts, Gert; Hendriks, Rudi W; Willemsen, Linette E M
炎症/感染
炎症
免疫/内分泌
发表日期：2026
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The potential immunomodulatory role of human milk oligosaccharides in prevention of viral infections and development of asthma in early life

人乳低聚糖在预防病毒感染和早期哮喘发生中的潜在免疫调节作用

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1572787
Rijks, Vera; Zuurveld, Marit; Garssen, Johan; Kostadinova, Atanaska I; Willemsen, Linette E M
炎症/感染
哮喘
免疫/内分泌
微生物学
发表日期：2025
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Secretor and non-secretor human milk oligosaccharides differentially modulate immune response in the presence of cow's milk allergen β-lactoglobulin in an in vitro sensitization model.

在体外致敏模型中，分泌型和非分泌型人乳寡糖在牛奶过敏原β-乳球蛋白存在的情况下，对免疫反应的调节作用存在差异

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1575656
Hellinga Anneke H, Zuurveld Marit, Mank Marko, Kraneveld Aletta D, Garssen Johan, Spann Kennedy, Bode Lars, Willemsen Linette E M, Van't Land Belinda
其它
Human
发表日期：2025
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HMOS 2'FL and 3FL prevent house dust mite induced proinflammatory cytokine release in vitro and decrease specific IgE production in a murine allergic asthma model

HMOS 2'FL 和 3FL 可抑制体外屋尘螨诱导的促炎细胞因子释放，并降低小鼠过敏性哮喘模型中特异性 IgE 的产生。

期刊:Frontiers in Nutrition
影响因子:5.1
doi:10.3389/fnut.2025.1491430
Zuurveld, Marit; de Kleer, Janna W M; Berends, Alinda J; Kooy, Manou M; Van Ark, Ingrid; Leusink-Muis, Thea; Kettelarij, Nienke; Folkerts, Gert; Garssen, Johan; Van't Land, Belinda; Willemsen, Linette E M
细胞生物学
哮喘
免疫/内分泌
发表日期：2025
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A Specific Ratio of Dietary Short-Chain and Long-Chain Fructo-Oligosaccharides Shifts the Immune Response Away from Type 2 in a Murine Model for House Dust Mite-Induced Asthma

膳食中短链和长链低聚果糖的特定比例可使小鼠屋尘螨诱发哮喘模型中的免疫反应从2型向更易发生的类型转变

期刊:Nutrients
影响因子:5
doi:10.3390/nu17223520
Verstegen, Roos E M; Zuurveld, Marit; Thijssen, Suzan; de Bruijn, Marjolein J W; van Ark, Ingrid; Diks, Mara A P; Garssen, Johan; Folkerts, Gert; Kostadinova, Atanaska I; Hendriks, Rudi W; Willemsen, Linette E M
哮喘
免疫/内分泌
发表日期：2025
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Lung Acetate Levels Decline in Correlation With Increased Type 2 Allergic Markers in a House Dust Mite Allergic Mouse Model

在屋尘螨过敏小鼠模型中，肺乙酸盐水平下降与 2 型过敏标志物升高呈正相关

期刊:Clinical and Translational Allergy
影响因子:4
doi:10.1002/clt2.70082
Verstegen, Roos E M; Sparidans, Rolf W; Kostadinova, Atanaska I; Garssen, Johan; Folkerts, Gert; Hendriks, Rudi W; Willemsen, Linette E M
Mouse
发表日期：2025
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DEVELOPING 3D PRINTING MODELS OF BRAIN TUMOURS

开发脑肿瘤的3D打印模型

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202507132
Janssen, Robine; Schulze, Henrike S; Nelissen, Claire M L; Valverde, Marta G; Hrynevich, Andrei; de Jong, Govardus A H; van Genderen, Anne Metje; Malda, Jos; Bastiaan-Net, Shanna; Willemsen, Linette E M; Masereeuw, Rosalinde; Ballesteros-Cillero, Rafael; Valli, Jessica; Melchels, Ferry P W; Leslie, Nicholas R
肿瘤
3D/类器官
神经科学
肿瘤免疫
发表日期：2023
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Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2'-Fucosyllactose and 3-Fucosyllactose.

卵清蛋白诱导的上皮活化指导单核细胞衍生的树突状细胞指导 T 细胞中的 2 型炎症，而 2'-岩藻糖基乳糖和 3-岩藻糖基乳糖对此有差异性调节

期刊:Journal of Innate Immunity
影响因子:3
doi:10.1159/000526528
Zuurveld Marit, Kiliaan Pien C J, van Grinsven Sophie E L, Folkerts Gert, Garssen Johan, Van't Land Belinda, Willemsen Linette E M
细胞生物学
炎症
发表日期：2023
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Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2'-fucosyllactose and short-chain galacto- and long-chain fructo-oligosaccharides

上皮细胞来源的含半乳糖凝集素-9的外泌体有助于2'-岩藻糖基乳糖以及短链半乳糖和长链果寡糖促进的免疫调节作用。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.1026031
Ayechu-Muruzabal, Veronica; de Boer, Merel; Blokhuis, Bart; Berends, Alinda J; Garssen, Johan; Kraneveld, Aletta D; Van't Land, Belinda; Willemsen, Linette E M
上皮细胞
细胞生物学
外泌体
免疫/内分泌
发表日期：2022
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