William O Cookson相关文献与解析，生知库

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

在小鼠和人类体内和体外模型中对二肽基肽酶 10 的操纵表明其在哮喘中具有保护作用

Youming Zhang, Thanushiyan Poobalasingam, Laura L Yates, Simone A Walker, Martin S Taylor, Lauren Chessum, Jackie Harrison, Loukia Tsaprouni, Ian M Adcock, Clare M Lloyd, William O Cookson, Miriam F Moffatt, Charlotte H Dean

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A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

雷帕霉素复合物 1/2 (mTORC1)/V-Akt 鼠胸腺瘤病毒致癌基因同源物 1 (AKT1)/组织蛋白酶 H 轴的机制靶点控制皮肤中的丝聚蛋白表达和加工，这是特应性皮炎患者皮肤屏障破坏的一种新机制

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.4

doi:10.1016/j.jaci.2016.09.052

Aishath S Naeem, Cristina Tommasi, Christian Cole, Stuart J Brown, Yanan Zhu, Benjamin Way, Saffron A G Willis Owen, Miriam Moffatt, William O Cookson, John I Harper, Wei-Li Di, Sara J Brown, Thomas Reinheckel, Ryan F L O'Shaughnessy

Global gene regulation during activation of immunoglobulin class switching in human B cells

人类 B 细胞免疫球蛋白类别转换激活过程中的整体基因调控

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/srep37988

Youming Zhang, David J Fear, Saffron A G Willis-Owen, William O Cookson, Miriam F Moffatt

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)

哮喘相关 PHD 指蛋白 11 基因 (PHF11) 的等位基因特异性转录受八聚体结合转录因子 1 (Oct-1) 调节

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.4

doi:10.1016/j.jaci.2010.12.015

Richard J Holt, Youming Zhang, Aristea Binia, Anna L Dixon, Claire Vandiedonck, William O Cookson, Julian C Knight, Miriam F Moffatt

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells

ORMDL3 调节 poly I:C 诱导的气道上皮细胞炎症反应

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

在小鼠和人类体内和体外模型中对二肽基肽酶 10 的操纵表明其在哮喘中具有保护作用

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

雷帕霉素复合物 1/2 (mTORC1)/V-Akt 鼠胸腺瘤病毒致癌基因同源物 1 (AKT1)/组织蛋白酶 H 轴的机制靶点控制皮肤中的丝聚蛋白表达和加工，这是特应性皮炎患者皮肤屏障破坏的一种新机制

Global gene regulation during activation of immunoglobulin class switching in human B cells

人类 B 细胞免疫球蛋白类别转换激活过程中的整体基因调控

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)

哮喘相关 PHD 指蛋白 11 基因 (PHF11) 的等位基因特异性转录受八聚体结合转录因子 1 (Oct-1) 调节