日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni

对甲氟喹-金属配合物中配体的研究揭示了其抗恶性疟原虫和曼氏血吸虫活性的结构决定因素

Villarreal, Wilmer; Quadros, Helenita Costa; Colina-Vegas, Legna; Aboagye, Sammy Y; Dziwornu, Godwin Akpeko; Ribeiro, Gabriel H; Barros, Ariane Isis; Kucharski, Dawid Jakub; Rahbari, Mahsa; Brandstädter, Christina; D'Alessandro, Sarah; Basilico, Nicoletta; Masike, Keabetswe; Mehlala, Nandi; Nobrega, Joaquim Araújo; Deflon, Victor M; Navarro, Maribel; Boratyński, Przemysław J; Chibale, Kelly; Williams, David L; Batista, Alzir A; Moreira, Diogo R M

β-Glucan Protects Against Sepsis-Induced Kupffer Cell Loss by Inhibiting Pyroptosis and Promoting Self-Renewal.

β-葡聚糖通过抑制细胞焦亡和促进自我更新来防止脓毒症引起的库普弗细胞丢失。

Adams Joseph, Li Tingting, Zhu Peilin, Garbe Chloe, Tu Fei, Casteel Jared, Yakubenko Valentin, Williams David L, Li Chuanfu, Wang Xiaohui

Toll-like receptor 4 induces trained innate immune tolerance in the heart in a model of stress-induced cardiomyopathy

在应激诱导心肌病模型中,Toll样受体4可诱导心脏产生训练性先天免疫耐受。

Lim, Kenji Rowel Q; Amrute, Junedh; Kovacs, Attila; Diwan, Abhinav; Williams, David L; Mann, Douglas L

The role of heme in sepsis induced Kupffer cell PANoptosis and senescence

血红素在脓毒症诱导的库普弗细胞凋亡和衰老中的作用

Li, Tingting; Adams, Joseph; Zhu, Peilin; Zhang, Tao; Tu, Fei; Gravitte, Amy; Zhang, Xiaojin; Liu, Li; Casteel, Jared; Yakubenko, Valentin; Williams, David L; Li, Chuanfu; Wang, Xiaohui

Heme drives cardiac endothelial senescence in sepsis via STING activation

血红素通过激活STING驱动脓毒症中的心脏内皮细胞衰老。

Li, Tingting; Zhu, Peilin; Wang, Jialing; Zhang, Tao; Adams, Joseph; Tu, Fei; Garbe, Chloe; Zhang, Xiaojin; Liu, Li; Singh, Krishna; Williams, David L; Li, Chuanfu; Wang, Xiaohui

Pleiotropic anti-cancer activities of novel non-covalent thioredoxin reductase inhibitors against triple negative breast cancer.

新型非共价硫氧还蛋白还原酶抑制剂对三阴性乳腺癌的多效性抗癌活性

Flowers Brenna, Rullo Abigail, Zhang An, Chang Keacha, Petukhova Valentina Z, Aboagye Sammy Y, Angelucci Francesco, Williams David L, Kregel Steven, Petukhov Pavel A, Kastrati Irida

HSPA12B Protects Against Age-Related Endothelial Cell Senescence by Regulating STING Degradation.

HSPA12B 通过调节 STING 降解来防止与年龄相关的内皮细胞衰老。

Li Tingting, Zhu Peilin, Adams Joseph, Tu Fei, Wang Jialing, Garbe Chloe, Dalal Suman, Singh Krishna, Zhang Xiaojin, Liu Li, Williams David L, Li Chuanfu, Wang Xiaohui

In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research.

体外实验方案展示了小鼠训练免疫的五个功能步骤:对生物标志物发现和转化研究的意义。

González-Pérez Maria, Baranda Jana, Pérez-Rodríguez Leticia, Conde Patricia, Calle-Fabregat Carlos de la, Berges-Buxeda Marcos J, Dimitrov Alexander, Arranz Javier, Rius-Rocabert Sergio, Zotta Alessia, Dopazo Ana, Poddar Nikita, Wang Xuedi, Nistal-Villán Estanislao, Duivenvoorden Raphaël, Madsen Joren C, Williams David L, Hasson Dan, Lozano-Ojalvo Daniel, Ginhoux Florent, O'Neill Luke A J, Ochando Jordi

Metabolic adaptations driving innate immune memory: mechanisms and therapeutic implications

代谢适应驱动先天免疫记忆:机制及治疗意义

Hao, Dan; McBride, Margaret A; Bohannon, Julia K; Hernandez, Antonio; Klein, Benjamin; Williams, David L; Sherwood, Edward R

Trained immunity enhances host resistance to infection in aged mice.

训练免疫可增强老年小鼠对感染的抵抗力

Hao Dan, Caja Katherine R, McBride Margaret A, Owen Allison M, Bohannon Julia K, Hernandez Antonio, Ali Sabah, Dalal Sujata, Williams David L, Sherwood Edward R