Williams Dominic P相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Contemporary perspective and practical application of glutamate dehydrogenase in nonclinical studies

谷氨酸脱氢酶在非临床研究中的当代视角和实际应用

期刊:Biomarkers in Medicine

影响因子:2.1

doi:10.1080/17520363.2025.2595911

Kodihalli, Ravindra C; Ameri, Mehrdad; Baker, Kevin S; Faber, Samantha C; Irizarry Rovira, Armando R; Jackson, Jonathan P; Norona, Leah M; Proctor, William R; Rae, Jessica M Caverly; Regev, Arie; Sakatis, Melanie Z; Williams, Dominic P; Zane, Doris; Rana, Payal

发表日期：2025

文献求助收藏

Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidates.

采用新的方法对共价抑制剂候选药物进行肝脏安全性评价

期刊:Toxicology Research

影响因子:2.1

doi:10.1093/toxres/tfaf054

Amberntsson Sara, Foster Alison J, Chouhan Bhavik, Wilkinson Stephen, Harlfinger Stephanie, Smith Graham, Kettle Jason G, Niedbala Michael, Kavanagh Stefan, Williams Dominic P

发表日期：2025

文献求助收藏

Apoptotic signatures allow early and rapid screening of drug-induced liver injury to accelerate drug discovery

细胞凋亡特征可用于早期快速筛查药物引起的肝损伤，从而加速药物研发。

doi:10.1038/s43856-025-01306-7

Hellgren, John; Chouhan, Bhavik; Uatay, Aydar; Elgendy, Ramy; Lindgren, Julia; Toki, Naoko; Bonetti, Alessandro; Chaudhari, Aditi; Pryde, Kenneth; Andersson, Patrik; Kalm, Marie; Karlsson, Fredrik; Sagemark, Johanna; Williams, Dominic P; Tan, Jennifer Y; John, Bino; Gallon, John

细胞生物学

发表日期：2025

文献求助收藏

Improved Detection of Drug-Induced Liver Injury by Integrating Predicted in vivo and in vitro Data

通过整合预测的体内和体外数据来改进药物性肝损伤的检测。

doi:10.1101/2024.01.10.575128

Seal, Srijit; Williams, Dominic P; Hosseini-Gerami, Layla; Mahale, Manas; Carpenter, Anne E; Spjuth, Ola; Bender, Andreas

发表日期：2024

文献求助收藏

Retraction notice to "Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity": J Hepatol 56(2012)1070-1079

撤稿声明：“HMGB1 和角蛋白-18 的分子形式作为对乙酰氨基酚临床肝毒性中细胞死亡方式和预后的机制生物标志物”：J Hepatol 56(2012)1070-1079

期刊:Journal of Hepatology

影响因子:33

doi:10.1016/j.jhep.2020.08.022

Antoine, Daniel J; Jenkins, Rosalind E; Dear, James W; Williams, Dominic P; McGill, Mitchell R; Sharpe, Matthew R; Craig, Darren G; Simpson, Kenneth J; Jaeschke, Hartmut; Park, B Kevin

细胞生物学

发表日期：2020

文献求助收藏

Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity

原代肝脏非实质细胞在3D球状体模型中的功能及其对对乙酰氨基酚肝毒性的贡献

期刊:Archives of Toxicology

影响因子:6.9

doi:10.1007/s00204-020-02682-w

Bell, Catherine C; Chouhan, Bhavik; Andersson, Linda C; Andersson, Håkan; Dear, James W; Williams, Dominic P; Söderberg, Magnus

细胞生物学

发表日期：2020

文献求助收藏

Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity

关注事项：饮食限制抑制对乙酰氨基酚肝毒性期间的细胞凋亡和HMGB1氧化，并促进炎症细胞募集

期刊:Molecular Medicine

影响因子:6.4

doi:10.1186/s10020-020-0140-z

Antoine, Daniel James; Williams, Dominic P; Kipar, Anja; Laverty, Hugh; Park, B Kevin

细胞生物学

发表日期：2020

文献求助收藏

Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity

撤稿声明：饮食限制可抑制对乙酰氨基酚肝毒性期间的细胞凋亡和HMGB1氧化，并促进炎症细胞募集。

期刊:Molecular Medicine

影响因子:6.4

doi:10.1186/s10020-020-00262-3

Antoine, Daniel James; Williams, Dominic P; Kipar, Anja; Laverty, Hugh; Park, B Kevin

细胞生物学

发表日期：2020

文献求助收藏

Multiscale modelling of drug transport and metabolism in liver spheroids

肝球体中药物转运和代谢的多尺度建模

期刊:Interface Focus

doi:10.1098/rsfs.2019.0041

Leedale, Joseph A; Kyffin, Jonathan A; Harding, Amy L; Colley, Helen E; Murdoch, Craig; Sharma, Parveen; Williams, Dominic P; Webb, Steven D; Bearon, Rachel N

发表日期：2020

文献求助收藏

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights

利用贝叶斯因果模型确定器官重量毒性：改进相对器官重量分析

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-020-63465-y

Lazic, Stanley E; Semenova, Elizaveta; Williams, Dominic P

发表日期：2020

文献求助收藏