日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacogenomic Synthetic Lethal Screens Reveal Hidden Vulnerabilities and New Therapeutic Approaches for Treatment of NF1-Associated Tumors

药物基因组学合成致死筛选揭示NF1相关肿瘤的潜在弱点和新的治疗方法

Williams, Kyle B; Larsson, Alex T; Keller, Bryant J; Chaney, Katherine E; Williams, Rory L; Bhunia, Minu M; Draper, Garrett M; Jubenville, Tyler A; Hudson, Wendy A; Georg, Gunda I; Moertel, Christopher L; Ratner, Nancy; Largaespada, David A

Techniques for Validating CRISPR Changes Using RNA-Sequencing Data.

利用RNA测序数据验证CRISPR改变的技术

Rathe Susan K, Marko Tracy A, Edwards Elizabeth N, Ridder Paige Hazelton, Varshney Jyotika, Williams Kyle B, Johnson James E, Moriarity Branden S, Largaespada David A

Multiomic analyses reveal new targets of polycomb repressor complex 2 in Schwann lineage cells and malignant peripheral nerve sheath tumors.

多组学分析揭示了雪旺细胞系细胞和恶性周围神经鞘瘤中多梳抑制复合物 2 的新靶点

Bhunia Minu M, Stehn Christopher M, Jubenville Tyler A, Novacek Ethan L, Larsson Alex T, Madala Mahathi, Suppiah Suganth, Velez-Reyes Germán L, Williams Kyle B, Sokolowski Mark, Williams Rory L, Finnerty Samuel J, Temiz Nuri A, Caride Ariel, Bhagwate Aditya V, Nagaraj Nagaswaroop K, Lee Jeong-Heon, Ordog Tamas, Zadeh Gelareh, Largaespada David A

Perinatal folate levels do not influence tumor latency or multiplicity in a model of NF1 associated plexiform-like neurofibromas

在NF1相关丛状样神经纤维瘤模型中,围产期叶酸水平不影响肿瘤潜伏期或肿瘤数量。

Williams, Kyle B; Marley, Andrew R; Tibbitts, Justin; Moertel, Christopher L; Johnson, Kimberly J; Linden, Michael A; Largaespada, David A; Marcotte, Erin L

Identification and characterization of a gene cluster required for proper rod shape, cell division, and pathogenesis in Clostridium difficile

艰难梭菌中维持正常杆状形态、细胞分裂和致病性所需的基因簇的鉴定和表征

Ransom, Eric M; Williams, Kyle B; Weiss, David S; Ellermeier, Craig D

Clostridium difficile extracytoplasmic function σ factor σV regulates lysozyme resistance and is necessary for pathogenesis in the hamster model of infection

艰难梭菌胞外功能σ因子σV调节溶菌酶抵抗力,并且是仓鼠感染模型中致病所必需的。

Ho, Theresa D; Williams, Kyle B; Chen, Yan; Helm, Richard F; Popham, David L; Ellermeier, Craig D