日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacogenomic Synthetic Lethal Screens Reveal Hidden Vulnerabilities and New Therapeutic Approaches for Treatment of NF1-Associated Tumors

药物基因组学合成致死筛选揭示NF1相关肿瘤的潜在弱点和新的治疗方法

Williams, Kyle B; Larsson, Alex T; Keller, Bryant J; Chaney, Katherine E; Williams, Rory L; Bhunia, Minu M; Draper, Garrett M; Jubenville, Tyler A; Hudson, Wendy A; Georg, Gunda I; Moertel, Christopher L; Ratner, Nancy; Largaespada, David A

Continuous evolution of user-defined genes at 1 million times the genomic mutation rate

用户自定义基因以基因组突变率的100万倍持续进化

Rix, Gordon; Williams, Rory L; Hu, Vincent J; Spinner, Aviv; Pisera, Alexander Olek; Marks, Debora S; Liu, Chang C

Multiomic analyses reveal new targets of polycomb repressor complex 2 in Schwann lineage cells and malignant peripheral nerve sheath tumors.

多组学分析揭示了雪旺细胞系细胞和恶性周围神经鞘瘤中多梳抑制复合物 2 的新靶点

Bhunia Minu M, Stehn Christopher M, Jubenville Tyler A, Novacek Ethan L, Larsson Alex T, Madala Mahathi, Suppiah Suganth, Velez-Reyes Germán L, Williams Kyle B, Sokolowski Mark, Williams Rory L, Finnerty Samuel J, Temiz Nuri A, Caride Ariel, Bhagwate Aditya V, Nagaraj Nagaswaroop K, Lee Jeong-Heon, Ordog Tamas, Zadeh Gelareh, Largaespada David A

Metabolic multistability and hysteresis in a model aerobe-anaerobe microbiome community.

模型需氧-厌氧微生物群落的代谢多稳定性和滞后现象

Khazaei Tahmineh, Williams Rory L, Bogatyrev Said R, Doyle John C, Henry Christopher S, Ismagilov Rustem F

Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK

靶向抑制双特异性磷酸酶 DUSP1 和 DUSP6 通过 JNK 抑制 MPNST 生长

Annmarie Ramkissoon, Katherine E Chaney, David Milewski, Kyle B Williams, Rory L Williams, Kwangmin Choi, Adam Miller, Tanya V Kalin, Joseph G Pressey, Sara Szabo, Mohammad Azam, David A Largaespada, Nancy Ratner