日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment

应用纠错测序技术进行体内调控性诱变性评估

Yauk, Carole L; Lynch, Anthony M; Dobrovolsky, Vasily N; Schuler, Maik; Smith-Roe, Stephanie L; Fitzgerald, Devon; Higgins, Jake; Honarvar, Naveed; Le Curieux, Frank; Matsumura, Shoji; Minocherhomji, Sheroy; Recio, Leslie; Salk, Jesse J; Sugiyama, Kei-Ichi; Suzuki, Takayoshi; Wills, John W; Marchetti, Francesco

Immunocompetent cell targeting by food-additive titanium dioxide.

食品添加剂二氧化钛对免疫活性细胞的靶向作用

Wills John W, Dabrowska Alicja, Robertson Jack, Miniter Michelle, Riedle Sebastian, Summers Huw D, Hewitt Rachel E, Fathima Adeeba, da Silva Alessandra Barreto, Bastos Carlos A P, Micklethwaite Stuart, Keita à sa V, Söderholm Johan D, Roy Nicole C, Otter Don, Jugdaohsingh Ravin, Mastroeni Pietro, Brown Andy P, Rees Paul, Powell Jonathan J

Critical comparison of BMD and TD(50) methods for the calculation of acceptable intakes for N-nitroso compounds

对BMD和TD(50)方法在计算N-亚硝基化合物可接受摄入量方面的比较研究

Thomas, Robert; Ponting, David J; Thresher, Andrew; Schlingemann, Joerg; Wills, John W; Johnson, George E

Alignment between Duplex Sequencing and transgenic rodent mutation assay data in the assessment of in vivo NDMA-induced mutagenesis

在评估体内NDMA诱导的诱变性时,双链测序和转基因啮齿动物突变试验数据的比对

Ashford, Anne L; Nachmanson, Daniela; Wills, John W; Higgins, Jacob E; Smith, Thomas H; Vavra, Kevin C; Dahalan, Farah A; Howe, Jonathan; Elloway, Joanne M; Salk, Jesse J; Doherty, Ann; Lynch, Anthony M

Resolution of historically discordant Ames test negative/rodent carcinogenicity positive N-nitrosamines using a sensitive, OECD-aligned design

利用灵敏的、符合经合组织标准的方案,解决历史上Ames试验阴性/啮齿动物致癌性阳性的N-亚硝胺不一致问题。

Thomas, Dean N; Wills, John W; Burman, Mark; Williams, Abbie N; Harte, Danielle S G; Buckley, Ruby A; Urquhart, Mike W; Bretonnet, Anne-Sophie; Jeffries, Benjamin; White, Angela T; Harvey, James S; Howe, Jonathan R; Lynch, Anthony M

Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting

体外浓度-反应数据解读在风险评估和监管决策中的应用:2022年IWGT定量分析专家工作组会议报告

Beal, Marc A; Chen, Guangchao; Dearfield, Kerry L; Gi, Min; Gollapudi, Bhaskar; Heflich, Robert H; Horibata, Katsuyoshi; Long, Alexandra S; Lovell, David P; Parsons, Barbara L; Pfuhler, Stefan; Wills, John; Zeller, Andreas; Johnson, George; White, Paul A

Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19

独特的肺细胞特征定义了致命性新冠肺炎中弥漫性肺泡损伤的时间演变过程

Milross, Luke; Hunter, Bethany; McDonald, David; Merces, George; Thomson, Amanda; Hilkens, Catharien M U; Wills, John; Rees, Paul; Jiwa, Kasim; Cooper, Nigel; Majo, Joaquim; Ashwin, Helen; Duncan, Christopher J A; Kaye, Paul M; Bayraktar, Omer Ali; Filby, Andrew; Fisher, Andrew J

OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration

OPTIMAL:一种用于基准测试分割和数据探索的优化成像质谱流式细胞术分析框架

Hunter, Bethany; Nicorescu, Ioana; Foster, Emma; McDonald, David; Hulme, Gillian; Fuller, Andrew; Thomson, Amanda; Goldsborough, Thibaut; Hilkens, Catharien M U; Majo, Joaquim; Milross, Luke; Fisher, Andrew; Bankhead, Peter; Wills, John; Rees, Paul; Filby, Andrew; Merces, George

An ovine model for investigation of the microenvironment of the male mammary gland

利用绵羊模型研究雄性乳腺微环境

Davies, Benjamin P; Crew, Rachael C; Cochrane, Anna L K; Davies, Katie; Figueiredo Baptista, André; Jeckel, Sonja; McCrone, Ian S; Niu, Youguo; Strugnell, Benjamin W; Waine, Katie; Fowden, Abigail L; Bryant, Clare E; Wills, John W; Giussani, Dino A; Hughes, Katherine

Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor

人类巨细胞病毒感染上皮细胞通过上调 ACE2 受体增加 SARS-CoV-2 重复感染

Marianne R Perera, Edward J D Greenwood, Thomas W M Crozier, Elizabeth G Elder, Janika Schmitt, Colin M Crump, Paul J Lehner, Mark R Wills, John H Sinclair; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research COVID BioResource Collaboration