Willsmore相关文献与解析，生知库 | 链接生命科学的每一步

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha

与 MOv18 IgE 相关的非过敏性荨麻疹样皮肤反应，MOv18 IgE 是一种首创的识别叶酸受体 α 的 IgE 抗体

Stavraka, Chara; Chauhan, Jitesh; Crescioli, Silvia; McSweeney, Sheila M; Pope, Amy; Gillett, Cheryl; Di Meo, Ashley; Prassas, Ioannis; Laddach, Roman; Stoker, Katie; McCraw, Alexandra J; Adams, Rebecca; Tull, Thomas J; Naban, Nabeel; Willsmore, Zena; Semkova, Kristina V; Grattan, Clive E H; McGrath, John; Till, Stephen J; Corrigan, Christopher J; Kristeleit, Rebecca; Tsoka, Sophia; Diamandis, Eleftherios P; Lacy, Katie E; Pinder, Sarah; Josephs, Debra H; Spicer, James; Bax, Heather J; Karagiannis, Sophia N

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发表日期：2025

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Circulating immunoregulatory B cell and autoreactive antibody profiles predict lack of toxicity to anti-PD-1 checkpoint inhibitor treatment in advanced melanoma

循环免疫调节性B细胞和自身反应性抗体谱可预测晚期黑色素瘤患者对PD-1检查点抑制剂治疗的毒性反应。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2025-011682

Willsmore, Zena N; Booth, Lucy; Patel, Akshay; Di Meo, Ashley; Prassas, Ioannis; Chauhan, Jitesh; Wu, Yin; Fitzpartick, Amanda; Stoker, Katie; Kapiris, Matthaios; Biswas, Dhruva; Perucha, Esperanza; Whittaker, Sean; Tsoka, Sophia; Diamandis, Eleftherios P; Middleton, Gary W; Tull, Thomas J; Papa, Sophie; Lacy, Katie E; Karagiannis, Sophia N

Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

肿瘤相关巨噬细胞是黑色素瘤当前和未来治疗的关键因素和靶点

期刊:Expert Review of Clinical Immunology

影响因子:3.7

doi:10.1080/1744666X.2024.2326626

Habib, Shabana; Osborn, Gabriel; Willsmore, Zena; Chew, Min Waye; Jakubow, Sophie; Fitzpatrick, Amanda; Wu, Yin; Sinha, Khushboo; Lloyd-Hughes, Hawys; Geh, Jenny L C; MacKenzie-Ross, Alastair D; Whittaker, Sean; Sanz-Moreno, Victoria; Lacy, Katie E; Karagiannis, Sophia N; Adams, Rebecca

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

细胞谱、抗体库和反应性揭示了黑色素瘤中具有自身免疫特征的失调反应

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-39042-y

Silvia Crescioli, Isabel Correa, Joseph Ng, Zena N Willsmore, Roman Laddach, Alicia Chenoweth, Jitesh Chauhan, Ashley Di Meo, Alexander Stewart, Eleni Kalliolia, Elena Alberts, Rebecca Adams, Robert J Harris, Silvia Mele, Giulia Pellizzari, Anna B M Black, Heather J Bax, Anthony Cheung, Mano Nakamur

Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade

调节性 B 细胞库缺陷使肺癌患者在接受检查点阻断治疗后易出现免疫相关毒性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-30863-x

Akshay J Patel, Zena N Willsmore, Naeem Khan, Alex Richter, Babu Naidu, Mark T Drayson, Sophie Papa, Andrew Cope, Sophia N Karagiannis, Esperanza Perucha, Gary W Middleton

Influencing tumor-associated macrophages in malignant melanoma with monoclonal antibodies

利用单克隆抗体影响恶性黑色素瘤中的肿瘤相关巨噬细胞

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2022.2127284

Adams, Rebecca; Osborn, Gabriel; Mukhia, Bipashna; Laddach, Roman; Willsmore, Zena; Chenoweth, Alicia; Geh, Jenny L C; MacKenzie Ross, Alastair D; Healy, Ciaran; Barber, Linda; Tsoka, Sophia; Sanz-Moreno, Victoria; Lacy, Katie E; Karagiannis, Sophia N

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

黑色素瘤患者体内丰富的循环和肿瘤驻留 TGF-β+ 调节性 B 细胞促进 FOXP3+ Tregs

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2022.2104426

Robert J Harris, Zena Willsmore, Roman Laddach, Silvia Crescioli, Jitesh Chauhan, Anthony Cheung, Anna Black, Jenny L C Geh, Alastair D MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Katie E Lacy, Sophia N Karagiannis

From Policy to Action: Co-Designing Research With Local Government to Advance Urban Greening

从政策到行动：与地方政府共同设计研究以推进城市绿化

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha

与 MOv18 IgE 相关的非过敏性荨麻疹样皮肤反应，MOv18 IgE 是一种首创的识别叶酸受体 α 的 IgE 抗体

Circulating immunoregulatory B cell and autoreactive antibody profiles predict lack of toxicity to anti-PD-1 checkpoint inhibitor treatment in advanced melanoma

循环免疫调节性B细胞和自身反应性抗体谱可预测晚期黑色素瘤患者对PD-1检查点抑制剂治疗的毒性反应。

Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

肿瘤相关巨噬细胞是黑色素瘤当前和未来治疗的关键因素和靶点

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

细胞谱、抗体库和反应性揭示了黑色素瘤中具有自身免疫特征的失调反应

Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade

调节性 B 细胞库缺陷使肺癌患者在接受检查点阻断治疗后易出现免疫相关毒性

Influencing tumor-associated macrophages in malignant melanoma with monoclonal antibodies

利用单克隆抗体影响恶性黑色素瘤中的肿瘤相关巨噬细胞

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

黑色素瘤患者体内丰富的循环和肿瘤驻留 TGF-β+ 调节性 B 细胞促进 FOXP3+ Tregs