Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signaling.
Dyr726 是一种可穿透血脑屏障的 PI3Kα、III 型受体酪氨酸激酶和 WNT 信号通路抑制剂
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doi:10.1101/2025.03.26.645490
Tandon Vasudha, Fistrovich Alessandra, Nogales Joaquina, Ferro Febe, Rokey Samantha N, Cabel Carly, Miller Amy Dunne, Yagel Mary, Duncan Christina, Atmasidha Aditi, Sharma Ira, Wilms Gerrit, Williams Karin, Elliott Richard, Chavez Timothy, Shaw Yeng, McMahon Aidan, Ginn Sean, Basantes L Emilia, Bedard Nathan, Gokhale Vijay, Ellis Nathan, Prescott Alan R, Smith Stuart J, Rahman Ruman, Becker Walter, Read Kevin D, Chalmers Anthony J, Carragher Neil, Masson Glenn R, Montfort William, Thorne Curtis, Hulme Christopher, Banerjee Sourav
