日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapid donor-specific single nucleotide variation detection by nanopore sequencing of ex vivo lung perfusate

利用纳米孔测序技术对离体肺灌注液进行快速供体特异性单核苷酸变异检测

Yamamoto, Haruchika; Allen, Jonathan; Sundby, Adam; Zuzarte, Philip; Keshavjee, Shaf; Simpson, Jared; Wilson, Gavin W; Yeung, Jonathan C

CRISPR-Cas Genome Editing in Ex Vivo Human Lungs to Rewire the Translational Path of Genome-Targeting Therapeutics.

利用 CRISPR-Cas 基因编辑技术在离体人肺中重塑基因组靶向治疗的转化路径

Mesaki Kumi, Yamamoto Haruchika, Juvet Stephen, Yeung Jonathan, Guan Zehong, Akhter Akhi, Yao Yan, Dickie Cameron, Mangat Henna, Wang Aizhou, Wilson Gavin W, Mariscal Andrea, Hu Jim, Davidson Alan R, Kleinstiver Benjamin P, Cypel Marcelo, Liu Mingyao, Keshavjee Shaf

Ex vivo lung perfusion moderates gene expression differences between cardiac death and brain death donor lungs

离体肺灌注可缓解心脏死亡和脑死亡供体肺之间的基因表达差异

Allen, Jonathan; Sage, Andrew T; Yamamoto, Haruchika; Wilson, Gavin W; Liu, Mingyao; Cypel, Marcelo; Keshavjee, Shaf; Yeung, Jonathan C

Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression

利用 CRISPR 介导的 IL-10 表达激活对供体肺进行免疫调节

Mesaki, Kumi; Juvet, Stephen; Yeung, Jonathan; Guan, Zehong; Wilson, Gavin W; Hu, Jim; Davidson, Alan R; Kleinstiver, Benjamin P; Cypel, Marcelo; Liu, Mingyao; Keshavjee, Shaf

Robust segregation of donor and recipient cells from single-cell RNA-sequencing of transplant samples

通过对移植样本进行单细胞RNA测序,实现供体细胞和受体细胞的可靠分离

Wilson, Gavin W; Duong, Allen; Moshkelgosha, Sajad; Bader, Gary; Keshavjee, Shaf; Martinu, Tereza; Juvet, Stephen C; Yeung, Jonathan C

scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing

scSNV:利用重复标签折叠进行精确的dscRNA-seq SNV共表达分析

Wilson, Gavin W; Derouet, Mathieu; Darling, Gail E; Yeung, Jonathan C

Towards personalized induction therapy for esophageal adenocarcinoma: organoids derived from endoscopic biopsy recapitulate the pre-treatment tumor

食管腺癌个体化诱导治疗:内镜活检来源的类器官可重现治疗前肿瘤特征

Derouet, Mathieu F; Allen, Jonathan; Wilson, Gavin W; Ng, Christine; Radulovich, Nikolina; Kalimuthu, Sangeetha; Tsao, Ming-Sound; Darling, Gail E; Yeung, Jonathan C

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

胰腺导管腺癌中不同突变特征与免疫活性增强相关因素的关联

Connor, Ashton A; Denroche, Robert E; Jang, Gun Ho; Timms, Lee; Kalimuthu, Sangeetha N; Selander, Iris; McPherson, Treasa; Wilson, Gavin W; Chan-Seng-Yue, Michelle A; Borozan, Ivan; Ferretti, Vincent; Grant, Robert C; Lungu, Ilinca M; Costello, Eithne; Greenhalf, William; Palmer, Daniel; Ghaneh, Paula; Neoptolemos, John P; Buchler, Markus; Petersen, Gloria; Thayer, Sarah; Hollingsworth, Michael A; Sherker, Alana; Durocher, Daniel; Dhani, Neesha; Hedley, David; Serra, Stefano; Pollett, Aaron; Roehrl, Michael H A; Bavi, Prashant; Bartlett, John M S; Cleary, Sean; Wilson, Julie M; Alexandrov, Ludmil B; Moore, Malcolm; Wouters, Bradly G; McPherson, John D; Notta, Faiyaz; Stein, Lincoln D; Gallinger, Steven

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

基于基因组重排模式的胰腺癌演化新模型

Notta, Faiyaz; Chan-Seng-Yue, Michelle; Lemire, Mathieu; Li, Yilong; Wilson, Gavin W; Connor, Ashton A; Denroche, Robert E; Liang, Sheng-Ben; Brown, Andrew M K; Kim, Jaeseung C; Wang, Tao; Simpson, Jared T; Beck, Timothy; Borgida, Ayelet; Buchner, Nicholas; Chadwick, Dianne; Hafezi-Bakhtiari, Sara; Dick, John E; Heisler, Lawrence; Hollingsworth, Michael A; Ibrahimov, Emin; Jang, Gun Ho; Johns, Jeremy; Jorgensen, Lars G T; Law, Calvin; Ludkovski, Olga; Lungu, Ilinca; Ng, Karen; Pasternack, Danielle; Petersen, Gloria M; Shlush, Liran I; Timms, Lee; Tsao, Ming-Sound; Wilson, Julie M; Yung, Christina K; Zogopoulos, George; Bartlett, John M S; Alexandrov, Ludmil B; Real, Francisco X; Cleary, Sean P; Roehrl, Michael H; McPherson, John D; Stein, Lincoln D; Hudson, Thomas J; Campbell, Peter J; Gallinger, Steven

RNASequel: accurate and repeat tolerant realignment of RNA-seq reads

RNASequel:精确且能容忍重复序列的RNA-seq读段重比对

Wilson, Gavin W; Stein, Lincoln D