日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosis

联合拮抗抑瘤素M(OSM)和白细胞介素6(IL-6)可同时发挥抗纤维化和抗炎作用,用于治疗肺纤维化。

Ratsimandresy, Rojo A; Doran, Emma; Dengler, Hart S; Headland, Sarah E; Wedeles, Christopher J; Guidi, Riccardo; Xu, Daqi; Liu, Jiatong; Shi, Yongchang; Wang, Jianyong; Uttarwar, Salil; Abbas, Alexander R; Sun, Tianhe; DePianto, Daryle J; Morshead, Katrina B; Arron, Joe; Rock, Jason R; Bevers, Jack; Yadav, Rajbharan; Ramalingam, Thirumalai; Gao, Xia; Brightbill, Hans D; Emson, Claire L; Jeet, Surinder; Arlantico, Alexander; Wong, Aaron; Yu, Sherman; Tran, Tiffany Hao; Leong, Laurie; Dohse, Monika; Austin, Cary; Caplazi, Patrick; Panettieri, Reynold A; Koziol-White, Cynthia; Jester, William F; Shaw, Andrey; Avraham, Shimrit; Menon, Hari; Darmanis, Spyros; Modrusan, Zora; Kajihara, Kimberly; Kanamori, Masakazu; Shimada, Hideaki; West, Nathaniel R; Nakamura, Gerald; Vander Heiden, Jason A; Wilson, Mark S

ncRNAs in Type-2 Immunity

2型免疫中的非编码RNA

Guidi, Riccardo; Wedeles, Christopher J; Wilson, Mark S

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

麻疹病毒感染会削弱人体原有的抗体,而这些抗体原本可以提供针对其他病原体的保护。

Mina, Michael J; Kula, Tomasz; Leng, Yumei; Li, Mamie; de Vries, Rory D; Knip, Mikael; Siljander, Heli; Rewers, Marian; Choy, David F; Wilson, Mark S; Larman, H Benjamin; Nelson, Ashley N; Griffin, Diane E; de Swart, Rik L; Elledge, Stephen J

Heat shock protein 70 is a positive regulator of airway inflammation and goblet cell hyperplasia in a mouse model of allergic airway inflammation

热休克蛋白70是过敏性气道炎症小鼠模型中气道炎症和杯状细胞增生的正向调节因子。

Yombo, Dan J K; Mentink-Kane, Margaret M; Wilson, Mark S; Wynn, Thomas A; Madala, Satish K

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

肿瘤进展位点2通过抑制树突状细胞中Ccl24的产生来减轻严重的过敏性气道炎症。

Kannan, Yashaswini; Li, Yanda; Coomes, Stephanie M; Okoye, Isobel S; Pelly, Victoria S; Sriskantharajah, Srividya; Gückel, Eva; Webb, Lauren; Czieso, Stephanie; Nikolov, Nikolay; MacDonald, Andrew S; Ley, Steven C; Wilson, Mark S

Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity

Th22细胞在体外形成与Th17细胞不同的Th谱系,具有独特的转录特性和Tbet依赖的Th1可塑性。

Plank, Maximilian W; Kaiko, Gerard E; Maltby, Steven; Weaver, Jessica; Tay, Hock L; Shen, Wei; Wilson, Mark S; Durum, Scott K; Foster, Paul S

MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells

含有microRNA的T调节细胞来源的外泌体抑制致病性T辅助细胞1(Th1)细胞

Okoye, Isobel S; Coomes, Stephanie M; Pelly, Victoria S; Czieso, Stephanie; Papayannopoulos, Venizelos; Tolmachova, Tanya; Seabra, Miguel C; Wilson, Mark S

Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity.

转录组学研究发现 Th2 细胞固有 miR-155 在介导过敏和抗蠕虫免疫中起着关键作用

Okoye Isobel S, Czieso Stephanie, Ktistaki Eleni, Roderick Kathleen, Coomes Stephanie M, Pelly Victoria S, Kannan Yashaswini, Perez-Lloret Jimena, Zhao Jimmy L, Baltimore David, Langhorne Jean, Wilson Mark S

Conventional NK cells can produce IL-22 and promote host defense in Klebsiella pneumoniae pneumonia

常规NK细胞可产生IL-22,并促进肺炎克雷伯菌肺炎中的宿主防御。

Xu, Xin; Weiss, Ido D; Zhang, Hongwei H; Singh, Satya P; Wynn, Thomas A; Wilson, Mark S; Farber, Joshua M

miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation

miR-182 和 miR-10a 是血吸虫和利什曼原虫相关炎症过程中 Treg 细胞分化和稳定性的关键调控因子。

Kelada, Samir; Sethupathy, Praveen; Okoye, Isobel S; Kistasis, Eleni; Czieso, Stephanie; White, Sandra D; Chou, David; Martens, Craig; Ricklefs, Stacy M; Virtaneva, Kimmo; Sturdevant, Dan E; Porcella, Stephen F; Belkaid, Yasmine; Wynn, Thomas A; Wilson, Mark S