日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rewriting Renal Fate: The Evolving Landscape of Adeno-Associated Virus-Mediated Kidney Gene Therapies

改写肾脏命运:腺相关病毒介导的肾脏基因疗法的演变格局

Hickman, Peyton G; Asokan, Aravind; Wilson, Matthew H

Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends

来自小棕蝠(Myotis lucifugus)的哺乳动物DNA转座子piggyBat的活性受到其自身转座子末端的限制。

Hickman, Alison B; Lannes, Laurie; Furman, Christopher M; Hong, Christina; Franklin, Lidiya; Ghirlando, Rodolfo; Ghosh, Arpita; Luo, Wentian; Konstantinidou, Parthena; Lorenzi, Hernán A; Grove, Anne; Haase, Astrid D; Wilson, Matthew H; Dyda, Fred

Urine-derived stem cells display homing, incorporation, and regeneration in human organoid and mouse models of acute kidney injury.

尿液来源的干细胞在人类类器官和急性肾损伤小鼠模型中表现出归巢、整合和再生能力

Bejoy Julie, Welch Richard C, Qian Eddie S, Williams Felisha M, Gibson-Corley Katherine N, Wilson Matthew H, Paragas Neal, Woodard Lauren E

Rac1 promotes proximal tubule kidney repair by coupling the actin cytoskeleton to mitochondrial function

Rac1通过将肌动蛋白细胞骨架与线粒体功能相偶联,促进近端肾小管修复。

M Viquez, Olga; Melzer, Meiling; Li, Shensen; Tantengco, Matthew; Dong, Xinyu; Sha, Eric; Huang, Jeffery; Krystofiak, Evan S; Hart, Rachel C; Luo, Wentian; Warren, Christian; Bayazid, Al-Borhan; Zhang, Richard; Bessho, Ryoichi; Haase, Volker H; Brakebusch, Cord; Inoue, Takanari; Brooks, Craig; Wilson, Matthew H; Terker, Andrew S; Arroyo, Juan P; Pozzi, Ambra; Zent, Roy; Bock, Fabian

Partial correction of cystinuria type A in mice via kidney-targeted transposon delivery.

通过肾脏靶向转座子递送部分纠正小鼠 A 型胱氨酸尿症

Woodard Lauren E, Welch Richard C, Menshikh Anna, Luo Wentian, Williams Felisha M, Peek Jennifer L, Sha Feng, Veach Ruth Ann, Kaja Aparna, Beckerman Thomas M, Ikizler Talat Alp, Wilson Matthew H

Efficient kidney gene transfer and proximal tubule transduction using self-complementary AAV.cc47 vectors.

利用自互补 AAV.cc47 载体实现高效的肾脏基因转移和近端肾小管转导。

Peek Jennifer L, Rosales Alan, Qi Julie, Feleke Lena, Menshikh Anna, Welch Richard C, Woodard Lauren E, Asokan Aravind, Wilson Matthew H

Dehydration promotes intracellular lipid synthesis and accumulation

脱水会促进细胞内脂质的合成和积累。

Carty, Joshua S; Selvasingh, Jazlyn; Zuchowski, Yvonne; Nam, Hyuck-Jin; Pénalva, Clothilde; Nanayakkara, Gayani; Jennings, Erin Q; Voss, Kelsey; Adame, Edith T; Tossberg, John T; Yap, Wei Sheng; Melzer, Meiling; Viquez, Olga; McCall, A Scott; Piotrowski, Elizabeth R; Bessho, Ryoichi; Cao, Shirong; Leaptrot, Katrina L; Schrimpe-Rutledge, Alexandra C; Codreanu, Simona G; Sherrod, Stacy D; McLean, John A; Trapani, Jonathan B; Cottam, Matthew A; Wan, Ma; Shrivastava, Deepti; Delker, Don; Wilson, Matthew H; Hasenour, Clinton M; Lantier, Louise; Chernova, Irene; Young, Jamey D; Haase, Volker H; Vazquez-Medina, Jose Pablo; Kosma, Dylan K; Kim, Peter; Cartailler, Jean-Philippe; Zhang, Mingzhi; Zent, Roy; Harris, Raymond C; Watts, Jason A; Terker, Andrew S; Bock, Fabian; Rathmell, Jeffrey C; Rodan, Aylin R; Arroyo, Juan P

Cell and gene therapy for kidney disease

肾脏疾病的细胞和基因疗法

Peek, Jennifer L; Wilson, Matthew H

Ligand-independent integrin β1 signaling supports lung adenocarcinoma development

配体非依赖性整合素β1信号通路促进肺腺癌的发生发展。

Haake, Scott M; Plosa, Erin J; Kropski, Jonathan A; Venton, Lindsay A; Reddy, Anupama; Bock, Fabian; Chang, Betty T; Luna, Allen J; Nabukhotna, Kateryna; Xu, Zhi-Qi; Prather, Rebecca A; Lee, Sharon; Tanjore, Harikrishna; Polosukhin, Vasiliy V; Viquez, Olga M; Jones, Angela; Luo, Wentian; Wilson, Matthew H; Rathmell, W Kimryn; Massion, Pierre P; Pozzi, Ambra; Blackwell, Timothy S; Zent, Roy

Gene therapy for kidney disease: targeting cystinuria

肾脏疾病的基因疗法:靶向胱氨酸尿症

Peek, Jennifer L; Wilson, Matthew H