日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Directed Functionalization of Recombinant Spider Silk Nonwoven Membranes with Antibodies Using Non-Canonical Amino Acids

利用非天然氨基酸对重组蜘蛛丝非织造膜进行抗体定向功能化

Lacombe, Claudia; Leonhardt, Charlotte; Humenik, Martin; Wiltschi, Birgit; Scheibel, Thomas

Site-Specific Antigen Immobilization Improves Autoantibody Binding Efficiency on the Luminex Platform

位点特异性抗原固定化可提高Luminex平台上的自身抗体结合效率

Kolanovic, Dajana; Hofner, Manuela; Huber, Jasmin; Weinhaeusel, Andreas; Wiltschi, Birgit

A Robust Bioprocess for the Global Incorporation of Noncanonical Amino Acids in Auxotrophic Hosts Produces Labeled Proteins at the Gram Scale

一种用于在营养缺陷型宿主中全面掺入非典型氨基酸的稳健生物工艺,可生产克级标记蛋白。

Fladischer, Patrik; Anderhuber, Niklaus; Murgu, Octavian; Hromić-Jahjefendić, Altijana; Pavkov-Keller, Tea; Gruber, Karl; Mairhofer, Juergen; Striedner, Gerald; Wiltschi, Birgit

Site-Specific Immobilization Boosts the Performance of a Galectin-1 Biosensor

位点特异性固定化可提高半乳糖凝集素-1生物传感器的性能

Kolanovic, Dajana; Pasupuleti, Rajeev; Wallner, Jakob; Mlynek, Georg; Wiltschi, Birgit

Aligning fermentation conditions with non-canonical amino acid addition strategy is essential for Nε-((2-azidoethoxy)carbonyl)-L-lysine uptake and incorporation into the target protein.

将发酵条件与非典型氨基酸添加策略相匹配,对于 Nε-((2-叠氮乙氧基)羰基)-L-赖氨酸的吸收和掺入目标蛋白至关重要

Hanaee-Ahvaz Hana, Baumann Marina Alexandra, Tauer Christopher, Albrecht Bernd, Wiltschi Birgit, Cserjan-Puschmann Monika, Striedner Gerald

Protocol for protein modification using oxalyl thioester-mediated chemoselective ligation.

利用草酰硫酯介导的化学选择性连接进行蛋白质修饰的方案

Terzani Francesco, Wang Chen, Rostami Simindokht, Desmet Rémi, Snella Benoît, Sénéchal Magalie, Wiltschi Birgit, Vicogne Jérôme, Melnyk Oleg, Agouridas Vangelis

Lectin-anticancer peptide fusion demonstrates a significant cancer-cell-selective cytotoxic effect and inspires the production of "clickable" anticancer peptide in Escherichia coli

凝集素-抗癌肽融合蛋白表现出显著的癌细胞选择性细胞毒性作用,并启发了在大肠杆菌中生产“可点击”抗癌肽。

Pasupuleti, Rajeev; Riedl, Sabrina; Saltor Núñez, Laia; Karava, Marianna; Kumar, Vajinder; Kourist, Robert; Turnbull, W Bruce; Zweytick, Dagmar; Wiltschi, Birgit

Residue-Specific Incorporation of the Non-Canonical Amino Acid Norleucine Improves Lipase Activity on Synthetic Polyesters

非天然氨基酸正亮氨酸的残基特异性引入可提高脂肪酶对合成聚酯的活性

Haernvall, Karolina; Fladischer, Patrik; Schoeffmann, Heidemarie; Zitzenbacher, Sabine; Pavkov-Keller, Tea; Gruber, Karl; Schick, Michael; Yamamoto, Motonori; Kuenkel, Andreas; Ribitsch, Doris; Guebitz, Georg M; Wiltschi, Birgit

'Clickable lectins': bioorthogonal reactive handles facilitate the directed conjugation of lectins in a modular fashion

“可点击凝集素”:生物正交反应基团以模块化方式促进凝集素的定向偶联

Tobola, Felix; Sylvander, Elise; Gafko, Claudia; Wiltschi, Birgit

Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs

非天然氨基酸对蛋白质-碳水化合物相互作用的影响:用氟化色氨酸类似物改造的凝集素的结构、动力学和碳水化合物亲和力

Tobola, Felix; Lelimousin, Mickael; Varrot, Annabelle; Gillon, Emilie; Darnhofer, Barbara; Blixt, Ola; Birner-Gruenberger, Ruth; Imberty, Anne; Wiltschi, Birgit