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Repeatability of semi-quantitative [(68)Ga]Ga-FAPI-46 PET/CT measurements in pancreatobiliary cancers: a test-retest study

胰胆肿瘤半定量[(68)Ga]Ga-FAPI-46 PET/CT测量的重复性：一项重测研究

期刊:European Journal of Nuclear Medicine and Molecular Imaging

Henrar, Rutger B; Cysouw, Matthijs C F; Palard-Novello, Xavier; Schwarte, Lothar A; Raijmakers, Pieter G H M; de Geus-Oei, Lioe-Fee; Vahrmeijer, Alexander L; Kazemier, Geert; Windhorst, Albert D; Boellaard, Ronald; Yaqub, Maqsood; Oprea-Lager, Daniela E; Swijnenburg, Rutger-Jan

One-Pot Base-Free Suzuki-Miyaura [(11)C]Methylation: Kinetic and Mechanistic Insights

一锅法无碱Suzuki-Miyaura [(11)C]甲基化反应：动力学和机理研究

期刊:Chemistry-A European Journal

影响因子:3.7

doi:10.1002/chem.202503251

Moreno, Oscar; Azzeggarh, Imad; Holland, Jason P; Windhorst, Albert D; Llop, Jordi

[(18)F]Trifluoroiodomethane - Enabling Photoredox-mediated Radical [(18)F]Trifluoromethylation for Positron Emission Tomography

[(18)F]三氟碘甲烷——用于正电子发射断层扫描的光氧化还原介导的自由基[(18)F]三氟甲基化

期刊:Angewandte Chemie-International Edition

影响因子:16.9

doi:10.1002/anie.202416901

Veth, Lukas; Windhorst, Albert D; Vugts, Danielle J

表观遗传

发表日期：2025

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A Radiolabeled Photoswitchable G Protein-Coupled Receptor Antagonist Enlightens Ligand Binding Kinetics Associated with Photoswitching

放射性标记的光开关G蛋白偶联受体拮抗剂揭示了与光开关相关的配体结合动力学

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/jacs.5c07349

Binkhorst, Lars C P; Josimovic, Ivana; De Boer, Bas; Simon, Icaro A; Van Der Aa, Frank; Zarzycka, Barbara A; De Esch, Iwan J P; Vischer, Henry F; Windhorst, Albert D; Wijtmans, Maikel; Leurs, Rob

信号转导

发表日期：2025

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Pharmacokinetic analysis and simplified uptake measures for tumour lesion [(18)F]F-AraG PET imaging in patients with non-small cell lung cancer

非小细胞肺癌患者肿瘤病灶[(18)F]F-AraG PET显像的药代动力学分析和简化摄取指标

期刊:European Journal of Nuclear Medicine and Molecular Imaging

影响因子:7.6

doi:10.1007/s00259-024-06931-3

Wijngaarden, Jessica E; Slebe, Maarten; Pouw, Johanna E E; Oprea-Lager, Daniela E; Schuit, Robert C; Dickhoff, Chris; Levi, Jelena; Windhorst, Albert D; Oordt, C Willemien Menke-van der Houven van; Thiele, Andrea; Bahce, Idris; Boellaard, Ronald; Yaqub, Maqsood

Development and evaluation of [(11)C]DPA-813 and [(18)F]DPA-814: novel TSPO PET tracers insensitive to human single nucleotide polymorphism rs6971

[(11)C]DPA-813 和 [(18)F]DPA-814 的开发和评估：新型 TSPO PET 示踪剂，对人类单核苷酸多态性 rs6971 不敏感

期刊:European Journal of Nuclear Medicine and Molecular Imaging

影响因子:7.6

doi:10.1007/s00259-025-07109-1

Beaino, Wissam; Jm Kooijman, Esther; Werry, Eryn L; Vellinga, Rens J; Van den Hoek, Johan; Sohler, Greta; Cumbers, Grace A; Genetzakis, Elijah; Harvey-Latham, Edward D; Schuit, Robert C; Kassiou, Michael; Windhorst, Albert D; Danon, Jonathan J

TSPO

发表日期：2025

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Neuroinflammation PET and long-term cognition and survival in symptomatic Alzheimer's disease

神经炎症PET与症状性阿尔茨海默病患者的长期认知和生存率

期刊:Alzheimers Research & Therapy

影响因子:7.6

doi:10.1186/s13195-025-01915-3

Rikken, Roos M; Yaqub, Maqsood; Coomans, Emma M; Dicks, Ellen; van der Vlies, Anne E; Windhorst, Albert D; Boellaard, Ronald; Pijnenburg, Yolande A L; Vijverberg, Everard G B; van de Giessen, Elsmarieke

Triflyl [(18)F]Fluoride as a Solution for Base-Sensitive Late-Stage Nucleophilic Aromatic (18)F-Fluorination Reactions

三氟甲磺酰[(18)F]氟化物作为碱敏感型后期亲核芳香(18)F-氟化反应的解决方案

期刊:Chemistry-A European Journal

影响因子:3.7

doi:10.1002/chem.202403127

Haveman, Lizeth Y F; de Kruijff, Anna M T; van Eeden, Sjoerd P P; Windhorst, Albert D; Vugts, Danielle J

发表日期：2025

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Exploration of Fluorinated Pyrazolidine-3,5-Diones for Positron Emission Tomography Imaging of the P2Y(12) Receptor in the Central Nervous System

利用氟化吡唑烷-3,5-二酮进行中枢神经系统P2Y(12)受体正电子发射断层扫描成像的研究

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500483

Stéen, E Johanna L; van der Schatte Olivier, Anne; van der Wildt, Berend; Pereira, Pedro; Alkayal, Khaled; Gabella Carena, Leopoldo J; Schuit, Robert C; Verlaan, Mariska; Beaino, Wissam; Zarzycka, Barbara A; de Esch, Iwan J P; Windhorst, Albert D

Aryl and Alkyl Radiotrifluoromethylation via Metallaphotoredox-Mediated Radical Cross-Coupling

通过金属光氧化还原介导的自由基交叉偶联进行芳基和烷基放射性三氟甲基化

Repeatability of semi-quantitative [(68)Ga]Ga-FAPI-46 PET/CT measurements in pancreatobiliary cancers: a test-retest study

胰胆肿瘤半定量[(68)Ga]Ga-FAPI-46 PET/CT测量的重复性：一项重测研究

One-Pot Base-Free Suzuki-Miyaura [(11)C]Methylation: Kinetic and Mechanistic Insights

一锅法无碱Suzuki-Miyaura [(11)C]甲基化反应：动力学和机理研究

[(18)F]Trifluoroiodomethane - Enabling Photoredox-mediated Radical [(18)F]Trifluoromethylation for Positron Emission Tomography

[(18)F]三氟碘甲烷——用于正电子发射断层扫描的光氧化还原介导的自由基[(18)F]三氟甲基化

A Radiolabeled Photoswitchable G Protein-Coupled Receptor Antagonist Enlightens Ligand Binding Kinetics Associated with Photoswitching

放射性标记的光开关G蛋白偶联受体拮抗剂揭示了与光开关相关的配体结合动力学

Pharmacokinetic analysis and simplified uptake measures for tumour lesion [(18)F]F-AraG PET imaging in patients with non-small cell lung cancer

非小细胞肺癌患者肿瘤病灶[(18)F]F-AraG PET显像的药代动力学分析和简化摄取指标

Development and evaluation of [(11)C]DPA-813 and [(18)F]DPA-814: novel TSPO PET tracers insensitive to human single nucleotide polymorphism rs6971

[(11)C]DPA-813 和 [(18)F]DPA-814 的开发和评估：新型 TSPO PET 示踪剂，对人类单核苷酸多态性 rs6971 不敏感

Neuroinflammation PET and long-term cognition and survival in symptomatic Alzheimer's disease

神经炎症PET与症状性阿尔茨海默病患者的长期认知和生存率

Triflyl [(18)F]Fluoride as a Solution for Base-Sensitive Late-Stage Nucleophilic Aromatic (18)F-Fluorination Reactions

三氟甲磺酰[(18)F]氟化物作为碱敏感型后期亲核芳香(18)F-氟化反应的解决方案

Exploration of Fluorinated Pyrazolidine-3,5-Diones for Positron Emission Tomography Imaging of the P2Y(12) Receptor in the Central Nervous System

利用氟化吡唑烷-3,5-二酮进行中枢神经系统P2Y(12)受体正电子发射断层扫描成像的研究