日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping genetic effects on splicing in ten thousand post-mortem brain samples reveals novel mediators of neurological disease risk

通过对一万份死后脑组织样本进行基因剪接效应分析,揭示了神经系统疾病风险的新介质。

Réal, Aline; Bp, Kailash; Dredge, Winston H; Muller, Benjamin Z; Jang, Beomjin; Tokolyi, Alex; Won, Hong-Hee; Humphrey, Jack; Raj, Towfique; Knowles, David A

Meta-analysis of genetic regulation of RNA editing in the human brain identifies new genes underlying neurological disease

对人类大脑中RNA编辑基因调控的荟萃分析发现了与神经系统疾病相关的新基因

Dredge, Winston H; Bp, Kailash; Réal, Aline; Muller, Benjamin Z; Jang, Beomjin; Fu, Ting; Seo, Hyomin; Won, Hong-Hee; Breen, Michael S; Xiao, Xinshu; Knowles, David A; Humphrey, Jack; Raj, Towfique

SingleBrain: A Meta-Analysis of Single-Nucleus eQTLs Linking Genetic Risk to Brain Disorders

SingleBrain:一项关于单核eQTL与遗传风险和脑部疾病关联的荟萃分析

Jang, Beomjin; Bp, Kailash; Tokolyi, Alex; Cuddleston, Winston H; Ravi, Ashvin; Jung, Sang-Hyuk; Naito, Tatsuhiko; Kim, Beomsu; Seo Kim, Min; Cho, Minyoung; Park, Mi-So; Rosen, Mikaela; Blanchard, Joel; Humphrey, Jack; Knowles, David A; Won, Hong-Hee; Raj, Towfique

Application and Safety of Externally Controlled Metronomic Drug Delivery to the Brain by an Implantable Smart Pump in a Sheep Model

在绵羊模型中,通过植入式智能泵实现外部控制的节律性脑部药物输送的应用及安全性

Chen, Thomas C; Wu, Winston H; Chang, Ki-Eun; Schönthal, Axel H; Gang, Eli S; Indravudh, Vic; Lobl, Thomas; Adell, Frank; Shachar, Yehoshua

Cytosine-to-uracil RNA editing is upregulated by pro-inflammatory stimulation of myeloid cells.

髓系细胞受到促炎刺激后,胞嘧啶到尿嘧啶的 RNA 编辑会上调

Seo Hyomin, Cuddleston Winston H, Fu Ting, Navarro Elisa, Parks Madison, Allan Amanda, Efthymiou Anastasia G, Breen Michael S, Xiao Xinshu, Raj Towfique, Humphrey Jack

Coordination of alternative splicing and alternative polyadenylation revealed by targeted long read sequencing

靶向长读长测序揭示了可变剪接和可变多聚腺苷酸化的协调机制

Zhiping Zhang,Bongmin Bae,Winston H Dredge,Pedro Miura

Cellular and genetic drivers of RNA editing variation in the human brain

人类大脑中RNA编辑变异的细胞和遗传驱动因素

Dredge, Winston H; Li, Junhao; Fan, Xuanjia; Kozenkov, Alexey; Lalli, Matthew; Khalique, Shahrukh; Dracheva, Stella; Mukamel, Eran A; Breen, Michael S

Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development

人类大脑发育过程中A-to-I编辑的时空和遗传调控

Dredge, Winston H; Fan, Xuanjia; Sloofman, Laura; Liang, Lindsay; Mossotto, Enrico; Moore, Kendall; Zipkowitz, Sarah; Wang, Minghui; Zhang, Bin; Wang, Jiebiao; Sestan, Nenad; Devlin, Bernie; Roeder, Kathryn; Sanders, Stephan J; Buxbaum, Joseph D; Breen, Michael S

Retraction Note to: High Pulsatility Flow Promotes Vascular Fibrosis by Triggering Endothelial EndMT and Fibroblast Activation

撤稿声明:高搏动性血流通过触发内皮细胞间质转化和成纤维细胞活化促进血管纤维化

Elliott, Winston H; Tan, Yan; Li, Min; Tan, Wei

Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea

肥胖男孩自主神经功能异常与胰岛素抵抗和阻塞性睡眠呼吸暂停风险相关

Oliveira, Flavia M S; Tran, Winston H; Lesser, Daniel J; Bhatia, Rajeev; Keens, Thomas G; Mittelman, Steven D; Davidson Ward, Sally L; Khoo, Michael C K