日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Use of anti-amyloid-β monoclonal antibodies in persons with Down syndrome Alzheimer's disease

在唐氏综合征合并阿尔茨海默病患者中使用抗β-淀粉样蛋白单克隆抗体

Farrell, Clíona; Saini, Fedal; Beidas, Mona M; Ryan, Natalie S; Strydom, Andre; Wiseman, Frances K

Multi-modal comparative phenotyping of knock-in mouse models of frontotemporal dementia/amyotrophic lateral sclerosis

对额颞叶痴呆/肌萎缩侧索硬化症敲入小鼠模型进行多模态比较表型分析

Boyanova, Sevda; Banks, Gareth; Lipina, Tatiana V; Bains, Rasneer Sonia; Forrest, Hamish; Stewart, Michelle; Carcolé, Mireia; Milioto, Carmelo; Isaacs, Adrian M; Wells, Sara E; Wiseman, Frances K

Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome-Alzheimer's disease.

唐氏综合征合并阿尔茨海默病患者的大脑中载脂蛋白 E 含量升高

Farrell Clíona, Buhidma Yazead, Mumford Paige, Heywood Wendy E, Hällqvist Jenny, Flores-Aguilar Lisi, Andrews Elizabeth, Rahimzadah Negin, Taso Orjona Stella, Doran Eric, Swarup Vivek, Head Elizabeth, Lashley Tammaryn, Mills Kevin, Toomey Christina E, Wiseman Frances K

Cell models for Down syndrome-Alzheimer's disease research

用于唐氏综合征-阿尔茨海默病研究的细胞模型

Wu, Yixing; West, Nicole R; Bhattacharyya, Anita; Wiseman, Frances K

Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models

出版商更正:利用小鼠模型对唐氏综合征相关APP/β淀粉样蛋白生物学改变进行遗传学解析

Tosh, Justin L; Rhymes, Elena R; Mumford, Paige; Whittaker, Heather T; Pulford, Laura J; Noy, Sue J; Cleverley, Karen; Walker, Matthew C; Tybulewicz, Victor L J; Wykes, Rob C; Fisher, Elizabeth M C; Wiseman, Frances K

Regional Microstructural Integrity in Relation to Gait Speed: The Atherosclerosis Risk in Communities Study

区域微观结构完整性与步速的关系:社区动脉粥样硬化风险研究

Farrell, Clíona; Mumford, Paige; Wiseman, Frances K; Sullivan, Kevin; Blackshear, Chad; Hughes, Timothy; Gottesman, Rebecca; Vemuri, Prashanthi; Mosley, Thomas; Griswold, Michael; Windham, B Gwen

Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome - a comprehensive morphometric analysis with active staining contrast-enhanced MRI

唐氏综合征Tc1小鼠模型小脑皮质内部颗粒层显著变薄,分子层表面积减少——基于活性染色对比增强MRI的综合形态计量分析

Ma, Da; Cardoso, Manuel J; Zuluaga, Maria A; Modat, Marc; Powell, Nick M; Wiseman, Frances K; Cleary, Jon O; Sinclair, Benjamin; Harrison, Ian F; Siow, Bernard; Popuri, Karteek; Lee, Sieun; Matsubara, Joanne A; Sarunic, Marinko V; Beg, Mirza Faisal; Tybulewicz, Victor L J; Fisher, Elizabeth M C; Lythgoe, Mark F; Ourselin, Sebastien

Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease

唐氏综合征和散发性阿尔茨海默病患者血浆中淀粉样蛋白、tau蛋白和细胞因子的生物标志物

Startin, Carla M; Ashton, Nicholas J; Hamburg, Sarah; Hithersay, Rosalyn; Wiseman, Frances K; Mok, Kin Y; Hardy, John; Lleó, Alberto; Lovestone, Simon; Parnetti, Lucilla; Zetterberg, Henrik; Hye, Abdul; Strydom, André

T(1), diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model

在阿尔茨海默病小鼠模型中,对海马进行T1加权成像、扩散张量成像和定量磁化转移成像。

Whittaker, Heather T; Zhu, Shenghua; Di Curzio, Domenico L; Buist, Richard; Li, Xin-Min; Noy, Suzanna; Wiseman, Frances K; Thiessen, Jonathan D; Martin, Melanie

Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome

全自动μMRI形态计量表型分析Tc1唐氏综合征小鼠模型

Powell, Nick M; Modat, Marc; Cardoso, M Jorge; Ma, Da; Holmes, Holly E; Yu, Yichao; O'Callaghan, James; Cleary, Jon O; Sinclair, Ben; Wiseman, Frances K; Tybulewicz, Victor L J; Fisher, Elizabeth M C; Lythgoe, Mark F; Ourselin, Sébastien