Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.
EGF 受体的不可逆抑制剂可以克服对吉非替尼的获得性耐药性
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0502860102
Kwak Eunice L, Sordella Raffaella, Bell Daphne W, Godin-Heymann Nadia, Okimoto Ross A, Brannigan Brian W, Harris Patricia L, Driscoll David R, Fidias Panos, Lynch Thomas J, Rabindran Sridhar K, McGinnis John P, Wissner Allan, Sharma Sreenath V, Isselbacher Kurt J, Settleman Jeffrey, Haber Daniel A